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4-Methylbenzene-1-carboximidamide hydrochloride

CAS No.
6326-27-8
Chemical Name:
4-Methylbenzene-1-carboximidamide hydrochloride
Synonyms
BUTTPARK 43\57-87;4-Methylbenzamidine, HCl;4-toluamidinehydrochloride;4-METHYLBENZIMIDAMIDE, HCL;p-toluamidine,monohydrochloride;4-METHYLBENZAMIDINE HYDROCHLORIDE;4-methylbenzimidamide hydrochloride;4-Methylbenzene-1-carboximidamideHCl;4-Methylbenzamidine Hydrochloride >4-Methylbenzamidine hydrochloride ,97%
CBNumber:
CB2424170
Molecular Formula:
C8H11ClN2
Molecular Weight:
170.64
MDL Number:
MFCD00040183
MOL File:
6326-27-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 00:28:49

4-Methylbenzene-1-carboximidamide hydrochloride Properties

Melting point 211-214°C
storage temp. Inert atmosphere,Room Temperature
solubility soluble in Methanol
form powder to crystal
color White to Almost white
Sensitive Hygroscopic
InChI InChI=1S/C8H10N2.ClH/c1-6-2-4-7(5-3-6)8(9)10;/h2-5H,1H3,(H3,9,10);1H
InChIKey MTDUPZAXNYELOU-UHFFFAOYSA-N
SMILES C1(C=CC(C)=CC=1)C(=N)N.Cl
CAS DataBase Reference 6326-27-8(CAS DataBase Reference)
FDA UNII 3AD6HT2FNA
UNSPSC Code 12352200

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36/37/39-37/39
WGK Germany  WGK 3
RTECS  XS4865000
Hazard Note  Irritant
HS Code  2925290090
Storage Class 11 - Combustible Solids

4-Methylbenzene-1-carboximidamide hydrochloride price More Price(68)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich CDS004524 4-methylbenzamidine hydrochloride AldrichCPR 100 mg $77.9 2026-04-30 Buy
TCI Chemical M2714 4-Methylbenzamidine Hydrochloride >98.0%(HPLC)(N) 6326-27-8 1g $44 2026-04-30 Buy
TCI Chemical M2714 4-Methylbenzamidine Hydrochloride >98.0%(HPLC)(N) 6326-27-8 5g $142 2026-04-30 Buy
Biosynth FM33871 4-Methylbenzamidine hydrochloride 6326-27-8 10g $163.3 2026-06-04 Buy
Biosynth FM33871 4-Methylbenzamidine hydrochloride 6326-27-8 25g $362.75 2026-06-04 Buy
Product number Packaging Price Buy
CDS004524 100 mg $77.9 Buy
M2714 1g $44 Buy
M2714 5g $142 Buy
FM33871 10g $163.3 Buy
FM33871 25g $362.75 Buy

4-Methylbenzene-1-carboximidamide hydrochloride Chemical Properties, Uses, Production

Uses

4-Methylbenzimidamide, HCl

Synthesis

Silanamine, N-(dimethylsilyl)-N,1,1,1-tetramethyl-

72525-60-1

p-Tolunitrile

104-85-8

4-Methylbenzene-1-carboximidamide hydrochloride

6326-27-8

Example 7: Synthesis of 4-methylbenzamidine hydrochloride Methanol (96 mg) was added dropwise to a solution of hexachloromethyl disilazane (484 mg) in dichloromethane (1 mL) at room temperature. Subsequently, the reaction mixture was cooled in an ice bath and trimethylsilyl trifluoromethanesulfonate (667 mg) was added slowly and dropwise. The resulting suspension was stirred at room temperature for 1 h. After that, p-toluenenitrile (351 mg) was added dropwise and the stirring was continued for 48 h at room temperature. Upon completion of the reaction, the suspension was poured into 2N aqueous sodium hydroxide solution and extracted with dichloromethane. The combined organic phases were dried over anhydrous sodium sulfate, followed by evaporation under reduced pressure to remove the solvent. The crude product was purified by chromatography on an aminosilica gel column (eluent: dichloromethane/methanol = 5/1), then to the purified product was added a 4N ethyl acetate solution of hydrogen chloride, and the solvent was again removed by evaporation under reduced pressure to give the final product, 4-methylbenzamidine hydrochloride (7 mg, 2% yield). 1H-NMR (270 MHz, DMSO-d6) δ: 2.41 (3H, s), 7.43 (2H, d, J=8.0 Hz), 7.74 (2H, d, J=8.0 Hz), 9.06 (2H, s), 9.30 (2H, s).

References

[1] Patent: US2003/158442, 2003, A1

Global Suppliers ( 145)
Supplier Tel Email Country ProdList Advantage
Suzhou Highfine Biotech Co., Ltd 0512-69209928 18796809688 zhouyingxiang@highfine.com China 1846 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Chembest Research Laboratories Limited 021-20908456 sales@BioChemBest.com China 5996 61
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Beijing HwrkChemical Technology Co., Ltd 89508211 18501085097 sales.bj@hwrkchemical.com China 9407 55
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Shijiazhuang Sdyano Fine Chemical Co., Ltd. 0311-89250318 13582355795 master@sjzsdyn.com China 2776 65
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Beijing Ouhe Technology Co., Ltd 13552068683 13522913783 2355560935@qq.com China 11777 60
Beijing Isomersyn Technology CO;LTD 010-82954736 13391601435 sales@isomersyn.com China 3294 57

View Latest Price from 4-Methylbenzene-1-carboximidamide hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Methylbenzene-1-carboximidamide hydrochloride pictures 2026-08-25 4-Methylbenzene-1-carboximidamide hydrochloride
6326-27-8
$2.20-8.80 1kg 99%min 100kg ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
4-Methylbenzene-1-carboximidamide hydrochloride pictures 2019-07-06 4-Methylbenzene-1-carboximidamide hydrochloride
6326-27-8
$1.00 1kg 95%-99% Career Henan Chemical Co

4-Methylbenzene-1-carboximidamide hydrochloride Spectrum

4-methylbenzenecarboximidamidemonohydrochloride BUTTPARK 43\57-87 4-METHYLBENZIMIDAMIDE, HCL 4-METHYLBENZENE-1-CARBOXIMIDAMIDE HYDROCHLORIDE 4-METHYLBENZAMIDINE HYDROCHLORIDE 4-toluamidinehydrochloride p-toluamidine,monohydrochloride 4-Methylbenzene-1-carboximidamideHCl 4-methylbenzimidamide hydrochloride 4-Methylbenzamidine, HCl 4-Methylbenzamidine hydrochloride ,97% 4-Methylbenzenecarboximidamide hydrochloride Benzenecarboximidamide, 4-methyl-, hydrochloride (1:1) 4-methylbenzenecarboximidamide chloride 4-Methylbenzamidine Hydrochloride > Benzenecarboximidamide, 4-methyl-, monohydrochloride [amino-(4-methylphenyl)methylidene]azanium 6326-27-8 blocks BuildingBlocks Carboxes Miscellaneous