4-Methylbenzene-1-carboximidamide hydrochloride
- CAS No.
- 6326-27-8
- Chemical Name:
- 4-Methylbenzene-1-carboximidamide hydrochloride
- Synonyms
- BUTTPARK 43\57-87;4-Methylbenzamidine, HCl;4-toluamidinehydrochloride;4-METHYLBENZIMIDAMIDE, HCL;p-toluamidine,monohydrochloride;4-METHYLBENZAMIDINE HYDROCHLORIDE;4-methylbenzimidamide hydrochloride;4-Methylbenzene-1-carboximidamideHCl;4-Methylbenzamidine Hydrochloride >4-Methylbenzamidine hydrochloride ,97%
- CBNumber:
- CB2424170
- Molecular Formula:
- C8H11ClN2
- Molecular Weight:
- 170.64
- MDL Number:
- MFCD00040183
- MOL File:
- 6326-27-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 211-214°C |
|---|---|
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | soluble in Methanol |
| form | powder to crystal |
| color | White to Almost white |
| Sensitive | Hygroscopic |
| InChI | InChI=1S/C8H10N2.ClH/c1-6-2-4-7(5-3-6)8(9)10;/h2-5H,1H3,(H3,9,10);1H |
| InChIKey | MTDUPZAXNYELOU-UHFFFAOYSA-N |
| SMILES | C1(C=CC(C)=CC=1)C(=N)N.Cl |
| CAS DataBase Reference | 6326-27-8(CAS DataBase Reference) |
| FDA UNII | 3AD6HT2FNA |
| UNSPSC Code | 12352200 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36/37/39-37/39 |
| WGK Germany | WGK 3 |
| RTECS | XS4865000 |
| Hazard Note | Irritant |
| HS Code | 2925290090 |
| Storage Class | 11 - Combustible Solids |
4-Methylbenzene-1-carboximidamide hydrochloride price More Price(68)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | CDS004524 | 4-methylbenzamidine hydrochloride AldrichCPR | 100 mg | $77.9 | 2026-04-30 | Buy | |
| TCI Chemical | M2714 | 4-Methylbenzamidine Hydrochloride >98.0%(HPLC)(N) | 6326-27-8 | 1g | $44 | 2026-04-30 | Buy |
| TCI Chemical | M2714 | 4-Methylbenzamidine Hydrochloride >98.0%(HPLC)(N) | 6326-27-8 | 5g | $142 | 2026-04-30 | Buy |
| Biosynth | FM33871 | 4-Methylbenzamidine hydrochloride | 6326-27-8 | 10g | $163.3 | 2026-06-04 | Buy |
| Biosynth | FM33871 | 4-Methylbenzamidine hydrochloride | 6326-27-8 | 25g | $362.75 | 2026-06-04 | Buy |
4-Methylbenzene-1-carboximidamide hydrochloride Chemical Properties, Uses, Production
Uses
4-Methylbenzimidamide, HCl
Synthesis
72525-60-1
104-85-8
6326-27-8
Example 7: Synthesis of 4-methylbenzamidine hydrochloride Methanol (96 mg) was added dropwise to a solution of hexachloromethyl disilazane (484 mg) in dichloromethane (1 mL) at room temperature. Subsequently, the reaction mixture was cooled in an ice bath and trimethylsilyl trifluoromethanesulfonate (667 mg) was added slowly and dropwise. The resulting suspension was stirred at room temperature for 1 h. After that, p-toluenenitrile (351 mg) was added dropwise and the stirring was continued for 48 h at room temperature. Upon completion of the reaction, the suspension was poured into 2N aqueous sodium hydroxide solution and extracted with dichloromethane. The combined organic phases were dried over anhydrous sodium sulfate, followed by evaporation under reduced pressure to remove the solvent. The crude product was purified by chromatography on an aminosilica gel column (eluent: dichloromethane/methanol = 5/1), then to the purified product was added a 4N ethyl acetate solution of hydrogen chloride, and the solvent was again removed by evaporation under reduced pressure to give the final product, 4-methylbenzamidine hydrochloride (7 mg, 2% yield). 1H-NMR (270 MHz, DMSO-d6) δ: 2.41 (3H, s), 7.43 (2H, d, J=8.0 Hz), 7.74 (2H, d, J=8.0 Hz), 9.06 (2H, s), 9.30 (2H, s).
References
[1] Patent: US2003/158442, 2003, A1
4-Methylbenzene-1-carboximidamide hydrochloride Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Suzhou Highfine Biotech Co., Ltd | 0512-69209928 18796809688 | zhouyingxiang@highfine.com | China | 1846 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chembest Research Laboratories Limited | 021-20908456 | sales@BioChemBest.com | China | 5996 | 61 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9407 | 55 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Shijiazhuang Sdyano Fine Chemical Co., Ltd. | 0311-89250318 13582355795 | master@sjzsdyn.com | China | 2776 | 65 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| Beijing Isomersyn Technology CO;LTD | 010-82954736 13391601435 | sales@isomersyn.com | China | 3294 | 57 |
View Latest Price from 4-Methylbenzene-1-carboximidamide hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-08-25 | 4-Methylbenzene-1-carboximidamide hydrochloride
6326-27-8
|
$2.20-8.80 | 1kg | 99%min | 100kg | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |
![]() |
2019-07-06 | 4-Methylbenzene-1-carboximidamide hydrochloride
6326-27-8
|
$1.00 | 1kg | 95%-99% | Career Henan Chemical Co |
-

- 4-Methylbenzene-1-carboximidamide hydrochloride
6326-27-8
- $2.20-8.80
- 99%min
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-

- 4-Methylbenzene-1-carboximidamide hydrochloride
6326-27-8
- $1.00
- 95%-99%
- Career Henan Chemical Co
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