Benzamidine
- CAS No.
- 618-39-3
- Chemical Name:
- Benzamidine
- Synonyms
- benziMidaMide;BENZENECARBOXIMIDAMIDE;phenylamidine;benzamidin;Benzamidine;benzylamidine;EINECS 210-546-3;Phenylmethanamidine;benzenecarbonamidine;α-Iminobenzenemethanamine
- CBNumber:
- CB8718710
- Molecular Formula:
- C7H8N2
- Molecular Weight:
- 120.15
- MDL Number:
- MFCD00042826
- MOL File:
- 618-39-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 65-70 °C |
|---|---|
| Boiling point | 208.5±23.0 °C(Predicted) |
| Density | 1.09±0.1 g/cm3(Predicted) |
| storage temp. | -20°C Freezer |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| pka | 11.90±0.40(Predicted) |
| form | powder or crystals |
| color | White to Off-White |
| BRN | 606020 |
| InChI | InChI=1S/C7H8N2/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H3,8,9) |
| InChIKey | PXXJHWLDUBFPOL-UHFFFAOYSA-N |
| SMILES | C1(C(N)=N)=CC=CC=C1 |
| FDA UNII | KUE3ZY3J1F |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H319 |
| Precautionary statements | P305+P351+P338 |
| PPE | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
| Hazard Codes | Xn |
| Risk Statements | 22-36 |
| Safety Statements | 26 |
| WGK Germany | 3 |
| F | 9-23 |
| HS Code | 29299000 |
| Storage Class | 11 - Combustible Solids |
Benzamidine price More Price(43)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 12072 | Benzamidine ≥95.0% | 618-39-3 | 10g | $326 | 2026-04-30 | Buy |
| Sigma-Aldrich | 12072 | Benzamidine ≥95.0% | 618-39-3 | 50g | $1100 | 2026-04-30 | Buy |
| Biosynth | FB35345 | Benzamidine | 618-39-3 | 5g | $471.15 | 2026-06-04 | Buy |
| Biosynth | FB35345 | Benzamidine | 618-39-3 | 10g | $659.6 | 2026-06-04 | Buy |
| ChemScene | CS-0103011 | Benzamidine ≥95% | 618-39-3 | 1g | $55 | 2026-06-04 | Buy |
Benzamidine Chemical Properties, Uses, Production
Uses
Benzamidine was used in the preparation of heparan sulfate-rich proteoglycan from mouse mammary epithelial cells. It has been used to prevent enzymatic degradation during the purification procedure of bovine factor XII (Hageman factor).
Definition
ChEBI: Benzamidine is a carboxamidine that is benzene carrying an amidino group. It has a role as a serine protease inhibitor. It is a member of benzenes and a carboxamidine. It is functionally related to a benzoic acid. It is a conjugate base of a benzamidine(1+).
Synthesis Reference(s)
The Journal of Organic Chemistry, 27, p. 1255, 1962 DOI: 10.1021/jo01051a033
Tetrahedron Letters, 31, p. 1969, 1990 DOI: 10.1016/S0040-4039(00)88891-7
Biochem/physiol Actions
Benzamidine is an inhibitor of plasmin and has been used in the radioimmunoassay of glucagon in human plasma. It prevents the destruction of Thyrotropin-releasing hormone (TRH) added to whole blood in vitro before radioimmunoassay of TRH.
Purification Methods
It is liberated from its hydrochloride chloride (below) by treatment with 5M NaOH, extracted into diethyl ether, dried (Na2SO4) and sublimed in vacuo.[Beilstein 9 H 280, 9 I 123, 9 II 199, 9 1264, 9 IV 898.]
Benzamidine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Jian Chao Chemical Technology Co., Ltd. | 150-2103-5486 18017383231 | 983544897@qq.com | China | 9335 | 55 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12973 | 57 | |
| Sinopharm Chemical Reagent Co,Ltd. | 86-21-63210123 | sj_scrc@sinopharm.com | China | 9791 | 79 |
| ShangHai YuanYe Biotechnology Co., Ltd. | 15026964105 | shyysw007@163.com | China | 4998 | 60 |
| Tianjin YongSheng Biotechnology Co., Ltd. | 022-60987737 13512258274;13820956092 | sales@immortalbio.com | China | 154 | 55 |
| Thermo Fisher Scientific | 800-810-5118 | cnchemical@thermofisher.com | China | 17752 | 75 |
View Latest Price from Benzamidine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-07-13 | BENZAMIDINE
618-39-3
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
 |
2021-07-10 | BENZAMIDINE
618-39-3
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
 |
2019-07-06 | BENZAMIDINE
618-39-3
|
$1.00 | 1kg | 95%-99% | 100kg | Career Henan Chemical Co |
-
- BENZAMIDINE
618-39-3
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- BENZAMIDINE
618-39-3
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- BENZAMIDINE
618-39-3
- $1.00
- 95%-99%
- Career Henan Chemical Co
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