4-Chloro-3-iodopyridine
- CAS No.
- 89167-34-0
- Chemical Name:
- 4-Chloro-3-iodopyridine
- Synonyms
- CHLORO-3-IODOPYRIDINE;4-Chloro-3-iodopyridine;3-Iodo-4-chloropyridine;Pyridine,4-chloro-3-iodo-;3-Iodo-4-iodomethyl-pyridine;4-Chloro-3-iodo-pyridine 97%;4-CHLORO-3-IODOPYRIDINE ISO 9001：2015 REACH
- CBNumber:
- CB2432896
- Molecular Formula:
- C5H3ClIN
- Molecular Weight:
- 239.44
- MDL Number:
- MFCD00234024
- MOL File:
- 89167-34-0.mol
- MSDS File:
- SDS
| Melting point | 69-70°C |
|---|---|
| Boiling point | 248.6±20.0 °C(Predicted) |
| Density | 2.052±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| form | solid |
| pka | 1.89±0.10(Predicted) |
| Appearance | Off-white to light yellow Solid |
| InChI | InChI=1S/C5H3ClIN/c6-4-1-2-8-3-5(4)7/h1-3H |
| InChIKey | GPFGRYFMMHDHGA-UHFFFAOYSA-N |
| SMILES | C1=NC=CC(Cl)=C1I |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS05,GHS07,GHS09 |
|---|---|
| Signal word | Danger |
| Hazard statements | H302-H315-H318-H400 |
| Precautionary statements | P273-P280-P301+P312+P330-P302+P352-P305+P351+P338+P310 |
| Hazard Codes | Xi,N,Xn |
| Risk Statements | 22-38-41-50 |
| Safety Statements | 26-39-61 |
| RIDADR | 3077 |
| WGK Germany | 3 |
| HazardClass | IRRITANT |
| PackingGroup | Ⅲ |
| HS Code | 2933399990 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Oral Aquatic Acute 1 Eye Dam. 1 Skin Irrit. 2 |
4-Chloro-3-iodopyridine price More Price(65)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 775576 | 4-Chloro-3-iodo-pyridine 97% | 89167-34-0 | 1g | $163 | 2023-06-20 | Buy |
| Biosynth | PDA16734 | 4-Chloro-3-iodopyridine | 89167-34-0 | 25g | $295 | 2026-06-04 | Buy |
| Apolloscientific | OR301298 | 4-Chloro-3-iodopyridine 98% | 89167-34-0 | 1g | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR301298 | 4-Chloro-3-iodopyridine 98% | 89167-34-0 | 5g | $35 | 2026-06-04 | Buy |
| Apolloscientific | OR301298 | 4-Chloro-3-iodopyridine 98% | 89167-34-0 | 25g | $160 | 2026-06-04 | Buy |
4-Chloro-3-iodopyridine Chemical Properties, Uses, Production
Synthesis
626-61-9
89167-34-0
The general procedure for the synthesis of 4-chloro-3-iodopyridine from 4-chloropyridine was as follows: suspension of 4-chloropyridine (10 g, 0.067 mol) in dry THF (150 mL) and slow dropwise addition of LDA (134 mL, 1 M hexane solution) at a temperature below -70 °C. The reaction mixture was stirred at -78 °C for 30 min before adding an anhydrous THF solution of I2 (17 g, 0.067 mol), keeping the internal temperature below -65 °C for 10 min. Subsequently, the reaction mixture was slowly warmed up to room temperature over a period of 2 hours and stirring was continued at room temperature for 30 minutes. Upon completion of the reaction, the mixture was poured into 20% aqueous Na2SO3 solution (100 mL) and extracted with EtOAc (100 mL, three times). The organic layer was washed sequentially with aqueous NaHCO3 (50 mL) and saturated aqueous NaCl (50 mL), dried and the solvent was evaporated. The product was purified by washing with petroleum ether (20 mL) to give 4-chloro-3-iodopyridine (6.2 g, 38% yield).'' HNMR (400 MHz, MeOD) δ 8.92 (s, 1H), 8.43-8.41 (d, 1H, J = 8Hz), 7.62-7.60 (d, 1H, J = 8Hz).
References
[1] Tetrahedron Letters, 2004, vol. 45, # 42, p. 7873 - 7877
[2] Journal of the American Chemical Society, 2002, vol. 124, # 4, p. 576 - 582
[3] Patent: WO2013/78254, 2013, A1. Location in patent: Paragraph 00359
[4] Heterocycles, 1996, vol. 43, # 8, p. 1641 - 1652
4-Chloro-3-iodopyridine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Amico Chemicals Co. LTD | 微信 18019252918 18019252918 | 1454668768@qq.com | China | 14933 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16305 | 64 |
| Shanghai Sunway Pharmaceutical Technology Co., Ltd | 13761987713 | hxzheng@sunwaypharm.cn | China | 8663 | 57 |
| SuZhou ShiYa Biopharmaceuticals, Inc. | 86(512)5235 8471 17715136450 | sales@shiyabiopharm.com | China | 4167 | 58 |
| Shanghai Witofly Chemical Co.,Ltd | sales@witofly.com | China | 2853 | 52 | |
| Shanghai Raise Chemical Technology Co.,Ltd | +86-021-50935922 | China | 7854 | 55 |
View Latest Price from 4-Chloro-3-iodopyridine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | 4-CHLORO-3-IODOPYRIDINE
89167-34-0
|
$1.10 | 1g | 99.00% | 100 Tons min | Dideu Industries Group Limited | |
 |
2020-01-09 | 4-CHLORO-3-IODOPYRIDINE
89167-34-0
|
$6.68 | 1KG | 99% | 1kg-1000kg | Career Henan Chemical Co |
-
- 4-CHLORO-3-IODOPYRIDINE
89167-34-0
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 4-CHLORO-3-IODOPYRIDINE
89167-34-0
- $6.68
- 99%
- Career Henan Chemical Co
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