PARAOXON
- CAS No.
- 311-45-5
- Chemical Name:
- PARAOXON
- Synonyms
- PARAOXON-ETHYL;E 600;PS610;ts219;ETICOL;PS-610;hc2072;Ts 219;HC 2072;Mintaco
- CBNumber:
- CB2463711
- Molecular Formula:
- C10H14NO6P
- Molecular Weight:
- 275.2
- MDL Number:
- MFCD00007316
- MOL File:
- 311-45-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 300°C |
|---|---|
| Boiling point | 169-170°C |
| Density | 1.274 g/mL at 25 °C(lit.) |
| refractive index |
n |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) |
| form | oil |
| color | yellow |
| Odor | slt odor |
| Water Solubility | 3.627g/L(20 ºC) |
| Merck | 13,7102 |
| BRN | 1915526 |
| Henry's Law Constant | 9.1×104 mol/(m3Pa) at 25℃, Duchowicz et al. (2020) |
| Stability | Moisture Sensitive |
| InChI | 1S/C10H14NO6P/c1-3-15-18(14,16-4-2)17-10-7-5-9(6-8-10)11(12)13/h5-8H,3-4H2,1-2H3 |
| InChIKey | WYMSBXTXOHUIGT-UHFFFAOYSA-N |
| SMILES | CCOP(=O)(OCC)Oc1ccc(cc1)[N+]([O-])=O |
| CAS DataBase Reference | 311-45-5 |
| EWG's Food Scores | 1-3 |
| FDA UNII | Q9CX8P80JW |
| ATC code | S01EB10 |
| EPA Substance Registry System | Paraoxon (311-45-5) |
| UNSPSC Code | 41116107 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS06,GHS09 |
|---|---|
| Signal word | Danger |
| Hazard statements | H300+H310-H410 |
| Precautionary statements | P262-P273-P280-P301+P310+P330-P302+P352+P310 |
| PPE | Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter |
| Hazard Codes | T+,N |
| Risk Statements | 26/27/28-50 |
| Safety Statements | 36/37/39-45-61 |
| RIDADR | UN 2810 6.1/PG 1 |
| WGK Germany | 3 |
| RTECS | TC2275000 |
| HazardClass | 6.1(a) |
| PackingGroup | I |
| Storage Class | 6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials |
| Hazard Classifications | Acute Tox. 1 Dermal Acute Tox. 1 Oral Aquatic Acute 1 Aquatic Chronic 1 |
| Hazardous Substances Data | 311-45-5(Hazardous Substances Data) |
| Toxicity | LD50 orally in rats: 1.8 mg/kg (Pickering, Malone) |
PARAOXON price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | D9286 | Paraoxon-ethyl ≥90%, oil | 311-45-5 | 1g | $591 | 2026-04-30 | Buy |
| Sigma-Aldrich | CRM36186 | Paraoxon-ethyl certified reference material, TraceCERT?, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland | 311-45-5 | 100MG | $101 | 2026-04-30 | Buy |
| Sigma-Aldrich | 36186 | Paraoxon-ethyl PESTANAL , analytical standard | 311-45-5 | 100mg | $102 | 2026-04-30 | Buy |
| Usbiological | P3107-72 | Paraoxon (Diethyl p-Nitrophenyl Phosphate) ≥95% | 311-45-5 | 250mg | $403 | 2026-06-03 | Buy |
| Usbiological | P3107-72 | Paraoxon (Diethyl p-Nitrophenyl Phosphate) ≥95% | 311-45-5 | 1g | $807 | 2026-06-03 | Buy |
PARAOXON Chemical Properties, Uses, Production
Chemical Properties
Oily Liquid
Chemical Properties
Paraoxon is an odorless, reddish-yellow oil. Fruity odor.
Uses
Insecticide.
Uses
A cholinesterase inhibitor
Uses
Paraoxon-ethyl has been used as a substratein paraoxonase (PON) activity assay. It has also been used as a lipase inhibitor to study the effects of anacetrapib on homotypic transfer from high density lipoproteinL3 (HDL3)toHDL2in vivo.
Definition
ChEBI: An aryl dialkyl phosphate where both the alkyl groups are ethyl and the aryl group is 4-nitrophenyl.
Synthesis Reference(s)
Tetrahedron Letters, 31, p. 3359, 1990 DOI: 10.1016/S0040-4039(00)89065-6
General Description
Reddish-yellow oily liquid with a faint fruity odor.
Reactivity Profile
Organophosphates are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.
Fire Hazard
Flash point data for PARAOXON are not available; however, PARAOXON is probably combustible.
Biochem/physiol Actions
Potent irreversible acetylcholinesterase inhibitor
Safety Profile
A deadly poison by ingestion,intraperitoneal, intravenous, subcutaneous, intramuscular,and parenteral routes. Mutation data reported. Humansystemic effects: coma, convulsions, miosis. Acholinesterase inhibitor. An insecticide. When heated todecompos
Potential Exposure
An organophosphate insecticide. Has been used as a medication.
Shipping
UN3018 Organophosphorus pesticides, liquid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials.
Incompatibilities
Keep away from alkaline materials and strong oxidizers. Contact with oxidizers can cause the release of toxic oxides of phosphorus. May react violently with antimony(V) pentafluoride. Incompatible with lead diacetate, magnesium, silver nitrate. In the presence of strong reducing agents such as hydrides, organophosphates form highly toxic and flammable phosphine gas.
Waste Disposal
In accordance with 40CFR165, follow recommendations for the disposal of pesticides and pesticide containers. Must be disposed properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office.
