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HSD-016

HSD-016 Structure
HSD-016 structure
CAS No.
946396-92-5
Chemical Name:
HSD-016
Synonyms
HSD-016;(2R)-1,1,1-Trifluoro-2-[3-[(2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-methylpiperazin-1-yl]sulfonylphenyl]propan-2-ol;Benzenemethanol, 3-[[(2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-methyl-1-piperazinyl]sulfonyl]-α-methyl-α-(trifluoromethyl)-, (αR)-
CBNumber:
CB24668017
Molecular Formula:
C21H21F7N2O3S
Molecular Weight:
514.46
MDL Number:
MOL File:
946396-92-5.mol
MSDS File:
SDS
Last updated:2025-10-29 15:43:00
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HSD-016 Properties

Melting point 102-104 °C
Boiling point 563.9±60.0 °C(Predicted)
Density 1.421±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 100 mg/mL (194.38 mM; Need ultrasonic)
pka 11.60±0.15(Predicted)
form Solid
color White to off-white
FDA UNII C4I13768E1

HSD-016 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0081349 HSD-016 99.95% 946396-92-5 5mg $412 2026-06-04 Buy
ChemScene CS-0081349 HSD-016 99.95% 946396-92-5 10mg $672 2026-06-04 Buy
ChemScene CS-0081349 HSD-016 99.95% 946396-92-5 25mg $1354 2026-06-04 Buy
ChemScene CS-0081349 HSD-016 99.95% 946396-92-5 50mg $2167 2026-06-04 Buy
ChemScene CS-0081349 HSD-016 99.95% 946396-92-5 100mg $3467 2026-06-04 Buy
Product number Packaging Price Buy
CS-0081349 5mg $412 Buy
CS-0081349 10mg $672 Buy
CS-0081349 25mg $1354 Buy
CS-0081349 50mg $2167 Buy
CS-0081349 100mg $3467 Buy

HSD-016 Chemical Properties, Uses, Production

Uses

HSD-016 is a potent, selective and orally active 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor with IC50 values of 11, 1 and 8 nM against human, mouse and rat 11β-HSD1, respectively. HSD-016 can be used for type 2 diabetes research[1].

References

[1] Wan ZK, et al. Synthesis of potent and orally efficacious 11β-hydroxysteroid dehydrogenase type 1 inhibitor HSD-016. J Org Chem. 2011 Sep 2;76(17):7048-55. DOI:10.1021/jo200958a

HSD-016 Preparation Products And Raw materials

Raw materials

Preparation Products

HSD-016 Suppliers

Global Suppliers ( 13)
Supplier Tel Email Country ProdList Advantage
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
ShangHai Biochempartner Co.,Ltd 177-54423994 17754423994 2853530910@QQ.com China 8000 62
InvivoChem 13549236410 sales@invivochem.cn China 6745 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Nantong QuanYi Biotechnology Co., Ltd 0513-66337626 18051384581 sales@chemhifuture.com China 5985 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58
https://hanhongsci.com/ 021-54306202 18917919676 info@hanhongsci.com China 29982 58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd 4000862158 18117107507 vip@med-life.cn China 4999 58
Suzhou Meidi Senuo Pharmaceutical Technology Co., Ltd. 13771642864 snhuyu_2008@126.com China 1186 58
Nanjing Shizhou Biology Technology Co.,Ltd 025-85560043 15850508050 cindy.huang@synzest.com China 11975 58
Supplier Advantage
Shanghai YuanYe Biotechnology Co., Ltd. 60
ShangHai Biochempartner Co.,Ltd 62
InvivoChem 58
TargetMol Chemicals Inc. 58
Nantong QuanYi Biotechnology Co., Ltd 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
https://hanhongsci.com/ 58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd 58
Suzhou Meidi Senuo Pharmaceutical Technology Co., Ltd. 58
Nanjing Shizhou Biology Technology Co.,Ltd 58

HSD-016 Spectrum

HSD-016(946396-92-5)1HNMR

946396-92-5 (HSD-016) Related Search:

5-β-Pregnane-3-α-21-diol-11-20-dione Methanone, [5-(2-furanyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-1-pyrrolidinyl- Emodin AZD 8329 Jujuboside B
11beta-Hydroxyprogesterone

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HSD-016 Benzenemethanol, 3-[[(2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-methyl-1-piperazinyl]sulfonyl]-α-methyl-α-(trifluoromethyl)-, (αR)- (2R)-1,1,1-Trifluoro-2-[3-[(2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-methylpiperazin-1-yl]sulfonylphenyl]propan-2-ol 946396-92-5 C21H21F7N2O3S