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(2S,4R)-4-METHYLGLUTAMIC ACID

CAS No.
31137-74-3
Chemical Name:
(2S,4R)-4-METHYLGLUTAMIC ACID
Synonyms
SYM 2081;(2S,4R)-4-MethylglutamicAci;(2S-R)-4-METHYLGLUTAMIC ACID;(2S,4R)-4-METHYLGLUTAMIC ACID;(4R)- 4-Methyl-L-glutamic Acid;L-erythro--Methylglutamic Acid;erythro-L-4-Methylglutamic Acid;ERYTHRO-4-METHYL-L-GLUTAMIC ACID;L-Glutamic acid, 4-methyl-, (4R)-;(2S,4R)-4-METHYLGLUTAMIC ACID USP/EP/BP
CBNumber:
CB2468367
Molecular Formula:
C6H11NO4
Molecular Weight:
161.16
MDL Number:
MFCD00937765
MOL File:
31137-74-3.mol
Last updated:2026-01-05 11:31:08
Product description Number Pack Size Price
SYM2081 ≥97%(HPLC) 0903 10 $214
(2S,4R)-4-MethylglutamicAcid M311575 50mg $1050
(2S,4R)-4-METHYL GLUTAMIC ACID 95.00% AAA0000080 50MG $1732.5
(2S,4R)-4-MethylglutamicAcid 11968 25mg $2000
(2S,4R)-4-METHYL GLUTAMIC ACID 95.00% AAA0000080 5MG $209

(2S,4R)-4-METHYLGLUTAMIC ACID Properties

Melting point 178 °C
Boiling point 287.44°C (rough estimate)
Density 1.3482 (rough estimate)
refractive index 1.4230 (estimate)
storage temp. Store at RT
solubility H2O: >10 mg/mL
pka 2.34±0.21(Predicted)
form solid
color white
InChI InChI=1S/C6H11NO4/c1-3(5(8)9)2-4(7)6(10)11/h3-4H,2,7H2,1H3,(H,8,9)(H,10,11)/t3-,4+/m1/s1
InChIKey KRKRAOXTGDJWNI-DMTCNVIQSA-N
SMILES C(O)(=O)[C@H](C[C@@H](C)C(O)=O)N
CAS DataBase Reference 31137-74-3(CAS DataBase Reference)
FDA UNII PQ76GL74VZ

SAFETY

Risk and Safety Statements

WGK Germany  3

(2S,4R)-4-METHYLGLUTAMIC ACID price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Tocris 0903 SYM2081 ≥97%(HPLC) 31137-74-3 10 $214 2021-12-16 Buy
TRC M311575 (2S,4R)-4-MethylglutamicAcid 31137-74-3 50mg $1050 2021-12-16 Buy
American Custom Chemicals Corporation AAA0000080 (2S,4R)-4-METHYL GLUTAMIC ACID 95.00% 31137-74-3 50MG $1732.5 2021-12-16 Buy
Medical Isotopes, Inc. 11968 (2S,4R)-4-MethylglutamicAcid 31137-74-3 25mg $2000 2021-12-16 Buy
American Custom Chemicals Corporation AAA0000080 (2S,4R)-4-METHYL GLUTAMIC ACID 95.00% 31137-74-3 5MG $209 2021-12-16 Buy
Product number Packaging Price Buy
0903 10 $214 Buy
M311575 50mg $1050 Buy
AAA0000080 50MG $1732.5 Buy
11968 25mg $2000 Buy
AAA0000080 5MG $209 Buy

(2S,4R)-4-METHYLGLUTAMIC ACID Chemical Properties,Uses,Production

Chemical Properties

White

Uses

A highly selective and potent agonist for kainate receptors.

Biological Activity

Potent and highly selective kainate receptor agonist, with an IC 50 for inhibition of [ 3 H]-kainate binding of 35 nM and almost 3,000- and 200-fold selectivity for kainate receptors over AMPA and NMDA receptors respectively. Also selectively inhibits the cloned excitatory amino acid transporter EAAT2 at higher concentrations. Also available as part of the Excitatory Amino Acid Transporter Inhibitor Tocriset™ and Kainate Receptor Tocriset™ .

IC 50

Kainate Receptor

(2S,4R)-4-METHYLGLUTAMIC ACID Preparation Products And Raw materials

(2S,4R)-4-METHYLGLUTAMIC ACID Suppliers

Global( 84)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 33024 60
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32470 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250 1026@dideu.com China 19933 58
Nextpeptide Inc
+86-0571-81612335 +8613336028439 sales@nextpeptide.com China 19908 58
Aladdin Scientific
tp@aladdinsci.com United States 57505 58
DONBOO AMINO ACID COMPANY
+8618051385538 donboo@donboo.com China 9363 58
Mainchem Co., Ltd. +86-0592-6210733 sale@mainchem.com China 32343 55
Suzhou Chenrui Biotechnology Co. LTD 17625585511 1580084073@qq.com China 978 58
J & K SCIENTIFIC LTD. 18210857532; 18210857532 jkinfo@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15838 69

View Lastest Price from (2S,4R)-4-METHYLGLUTAMIC ACID manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
SYM 2081 pictures 2026-01-05 SYM 2081
31137-74-3
US $87.00-313.00 / mg 99.63% 10g TargetMol Chemicals Inc.
  • SYM 2081 pictures
  • SYM 2081
    31137-74-3
  • US $87.00-313.00 / mg
  • 99.63%
  • TargetMol Chemicals Inc.

(2S,4R)-4-METHYLGLUTAMIC ACID Spectrum

SYM 2081 ERYTHRO-4-METHYL-L-GLUTAMIC ACID (2S,4R)-(+)-2-Amino-4-methylpentanedioic acid (2S,4R)-4-METHYLGLUTAMIC ACID (2S,4R)-(+)-2-AMINO-4-METHYLPENTANEDIOIC ACID 99% (2S-R)-4-METHYLGLUTAMIC ACID (4R)- 4-Methyl-L-glutamic Acid erythro-L-4-Methylglutamic Acid L-erythro--Methylglutamic Acid (2S,4R)-(+)-2-Amino-4-methylpentanedioic acid,99% L-Glutamic acid, 4-methyl-, (4R)- (2S,4R)-4-MethylglutamicAci (2S,4R)-4-METHYLGLUTAMIC ACID USP/EP/BP 31137-74-3 Cell Signaling and Neuroscience Cell Biology BioChemical Ionotropic Glutamate Receptor Modulators Ion Channels Ligand-Gated Ion Channels Amino Acids 13C, 2H, 15N Amino Acids & Derivatives Chiral Reagents Neurochemicals