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ChemicalBook >> CAS DataBase List >>(2S,4R)-4-Methylglutamic acid

(2S,4R)-4-Methylglutamic acid

(2S,4R)-4-Methylglutamic acid Structure
(2S,4R)-4-Methylglutamic acid structure
CAS No.
31137-74-3
Chemical Name:
(2S,4R)-4-Methylglutamic acid
Synonyms
SYM 2081;(2S,4R)-4-MethylglutamicAci;(2S-R)-4-METHYLGLUTAMIC ACID;(2S,4R)-4-Methylglutamic acid;(4R)- 4-Methyl-L-glutamic Acid;L-erythro--Methylglutamic Acid;erythro-L-4-Methylglutamic Acid;ERYTHRO-4-METHYL-L-GLUTAMIC ACID;L-Glutamic acid, 4-methyl-, (4R)-;(2S,4R)-4-METHYLGLUTAMIC ACID USP/EP/BP
CBNumber:
CB2468367
Molecular Formula:
C6H11NO4
Molecular Weight:
161.16
MDL Number:
MFCD00937765
MOL File:
31137-74-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:51:19
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(2S,4R)-4-Methylglutamic acid Properties

Melting point 178 °C
Boiling point 287.44°C (rough estimate)
Density 1.3482 (rough estimate)
refractive index 1.4230 (estimate)
storage temp. Store at RT
solubility H2O: >10 mg/mL
form solid
pka 2.34±0.21(Predicted)
color white
InChI InChI=1S/C6H11NO4/c1-3(5(8)9)2-4(7)6(10)11/h3-4H,2,7H2,1H3,(H,8,9)(H,10,11)/t3-,4+/m1/s1
InChIKey KRKRAOXTGDJWNI-DMTCNVIQSA-N
SMILES C(O)(=O)[C@H](C[C@@H](C)C(O)=O)N
CAS DataBase Reference 31137-74-3(CAS DataBase Reference)
FDA UNII PQ76GL74VZ

SAFETY

Risk and Safety Statements

WGK Germany  3

(2S,4R)-4-Methylglutamic acid price More Price(42)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 41348 SYM 2081 ≥95% 31137-74-3 1mg $28 2026-04-30 Buy
Cayman Chemical 41348 SYM 2081 ≥95% 31137-74-3 5mg $104 2026-04-30 Buy
Cayman Chemical 41348 SYM 2081 ≥95% 31137-74-3 10mg $193 2026-04-30 Buy
Cayman Chemical 41348 SYM 2081 ≥95% 31137-74-3 25mg $447 2026-04-30 Buy
Usbiological 282740 (2S,4R)-4-Methylglutamic Acid ≥97% 31137-74-3 5mg $641 2026-06-03 Buy
Product number Packaging Price Buy
41348 1mg $28 Buy
41348 5mg $104 Buy
41348 10mg $193 Buy
41348 25mg $447 Buy
282740 5mg $641 Buy

(2S,4R)-4-Methylglutamic acid Chemical Properties, Uses, Production

Chemical Properties

White

Uses

A highly selective and potent agonist for kainate receptors.

Biological Activity

Potent and highly selective kainate receptor agonist, with an IC 50 for inhibition of [ 3 H]-kainate binding of 35 nM and almost 3,000- and 200-fold selectivity for kainate receptors over AMPA and NMDA receptors respectively. Also selectively inhibits the cloned excitatory amino acid transporter EAAT2 at higher concentrations. Also available as part of the Excitatory Amino Acid Transporter Inhibitor Tocriset™ and Kainate Receptor Tocriset™ .

IC 50

Kainate Receptor

(2S,4R)-4-Methylglutamic acid Preparation Products And Raw materials

Raw materials

2-Methyl-4-oxopentanedioic acid (2S,4S)-4-Methylglutamic acid

Preparation Products

(2S,4R)-4-Methylglutamic acid Suppliers

Global Suppliers ( 89)
Supplier Tel Email Country ProdList Advantage
Suzhou Chenrui Biotechnology Co. LTD 17625585511 1580084073@qq.com China 992 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 18149758185 sales-cpd@caerulumpharma.com China 3493 58
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696，15000506266 15000506266 China 4859 55
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8435 60
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Supplier Advantage
Suzhou Chenrui Biotechnology Co. LTD 58
J & K SCIENTIFIC LTD. 76
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Chemsky（shanghai）International Co.,Ltd. 50
ShangHai Caerulum Pharma Discovery Co., Ltd. 58
Bide Pharmatech Ltd. 60
Shanghai Lollane Biological Technology Co.,Ltd. 55
EMMX Biotechnology LLC 60
Shanghai EFE Biological Technology Co., Ltd. 58
Shanghai YuanYe Biotechnology Co., Ltd. 60

View Latest Price from (2S,4R)-4-Methylglutamic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
SYM 2081 pictures 2026-07-14 SYM 2081
31137-74-3
 $61.00-222.00 99.63% 10g TargetMol Chemicals Inc.
SYM 2081 pictures 2026-06-30 SYM 2081
31137-74-3
 1KG 97% 20Tons Shaanxi Dideu New Materials Co. Ltd
  • SYM 2081 pictures
  • SYM 2081
    31137-74-3
  • $61.00-222.00
  • 99.63%
  • TargetMol Chemicals Inc.
  • SYM 2081 pictures
  • SYM 2081
    31137-74-3
  • 97%
  • Shaanxi Dideu New Materials Co. Ltd

(2S,4R)-4-Methylglutamic acid Spectrum

(2S,4R)-4-METHYLGLUTAMIC ACID(31137-74-3)1HNMR

31137-74-3 ((2S,4R)-4-Methylglutamic acid) Related Search:

DL-2-Methylglutamic acid (2S,1'S,2'S)-2-(Carboxycyclopropyl)glycine D-2-Methylglutamic acid (2S,3R,4S)-CCG (2R,3R)-3-Methylglutamic acid
(1S,3R)-ACPD DCG IV N-Methylglutamic acid LY 341495 L-trans-Pyrrolidine-2,4-dicarboxylic acid
(+/-)-1-Aminocyclopentane-cis-1,3-dicarboxylic acid Fmoc-Gla(OtBu)2-OH Z-L-Gla(OtBu)2-OH (2S,4R)-4-Methylglutamic acid (R)-2-Amino-2-methylpentanedioic acid
(2S,4S)-4-Methylglutamic acid hydrochloride (2S,4S)-4-Methylglutamic acid H-Gla-OH

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SYM 2081 ERYTHRO-4-METHYL-L-GLUTAMIC ACID (2S,4R)-(+)-2-Amino-4-methylpentanedioic acid (2S,4R)-(+)-2-AMINO-4-METHYLPENTANEDIOIC ACID 99% (2S-R)-4-METHYLGLUTAMIC ACID (4R)- 4-Methyl-L-glutamic Acid erythro-L-4-Methylglutamic Acid L-erythro--Methylglutamic Acid (2S,4R)-(+)-2-Amino-4-methylpentanedioic acid,99% L-Glutamic acid, 4-methyl-, (4R)- (2S,4R)-4-MethylglutamicAci (2S,4R)-4-METHYLGLUTAMIC ACID USP/EP/BP (2S,4R)-4-Methylglutamic acid 31137-74-3 Cell Signaling and Neuroscience Cell Biology BioChemical Ionotropic Glutamate Receptor Modulators Ion Channels Ligand-Gated Ion Channels Amino Acids 13C, 2H, 15N Amino Acids & Derivatives Chiral Reagents Neurochemicals