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(+/-)-BAY K 8644

CAS No.
93468-89-4
Chemical Name:
(+/-)-BAY K 8644
Synonyms
BAY K-8644 (+/-);(+/-)-BAY K 8644;(±)-Bay K 8644 - CAS 93468-89-4 - Calbiochem;(+)-(S)-1,4-dihydro-2,6-dimethyl-3-nitro-4-(2-trifluoromethylphenyl)pyridine-5-carboxylic acid;1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-(2-[TRIFLUOROMETHYL]PHENYL)PYRIDINE-3-CARBOXYLIC ACID METHYL ESTER;1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-[2-(TRIFLUOROMETHYL)PHENYL]-3-PYRIDINECARBOXYLIC ACID, METHYL ESTER;1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-[2'-(TRIFLUOROMETHYL)PHENYL]-3-PYRIDINECARBOXYLIC ACID METHYL ESTER
CBNumber:
CB2471785
Molecular Formula:
C16H15F3N2O4
Molecular Weight:
356.3
MDL Number:
MFCD00036697
MOL File:
93468-89-4.mol
Last updated:2023-05-04 17:34:43

(+/-)-BAY K 8644 Properties

Melting point 166-172 °C
storage temp. 2-8°C
solubility DMSO: 184 mg/mL
form Yellow solid

SAFETY

Risk and Safety Statements

Hazard Codes  Xi
Risk Statements  36/38
Safety Statements  26-36
WGK Germany  3

(+/-)-BAY K 8644 price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Axon Medchem Axon1697 BAY K 8644 10mg $110 2026-05-19 Buy
Axon Medchem Axon1697 BAY K 8644 50mg $396 2026-05-19 Buy
Product number Packaging Price Buy
Axon1697 10mg $110 Buy
Axon1697 50mg $396 Buy

(+/-)-BAY K 8644 Chemical Properties, Uses, Production

Definition

ChEBI: Methyl 2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-3-carboxylate is a pentasubstituted dihydropyridine carrying methoxycarbonyl, 2-(trifluoromethyl)phenyl and nitro substituents at positions 3, 4 and 5 respectively as well as two methyl substituents at positions 2 and 6. It is a dihydropyridine, a methyl ester, a C-nitro compound and a member of (trifluoromethyl)benzenes.

General Description

Synthetic dihydropyridine derivative that acts as an active Ca2+ slow channel agonist in neuroendocrine, muscle, thyroid and other cell types. Prolongs single channel open time without affecting the close time. An L-type Ca2+ channel agonist. Composed of two optical isomers. The (-)-enantiomer has strong vasoconstrictive, positive inotropic, and Ca2+ agonistic properties, whereas the (+)-enantiomer has weakly vasodilating, negative inotropic, and Ca2+ antagonistic properties. The net effect of the racemic mix is that of the negative enantiomer. Promotes β-cell proliferation/regeneration.

Biochem/physiol Actions

Primary TargetL-type Ca2+ channel

(+/-)-BAY K 8644 Preparation Products And Raw materials

Raw materials

Preparation Products

(+/-)-BAY K 8644 Suppliers

Global Suppliers ( 69)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
ShangHai Biochempartner Co.,Ltd 177-54423994 17754423994 2853530910@QQ.com China 8000 62
Chuzhou KeMail Chemical Technology Co., Ltd 0550-5196001 15000891977 wj520wjxby@126.com China 1940 55
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 sales@sarms4muscle.com China 10378 58
Career Henan Chemica Co +86-0371-86658258 +86-13203830695 laboratory@coreychem.com China 30203 58
ShangHai ChuanQian Chemcial Technique Centre 15869524721 3525679403@qq.com China 4565 58
Shanghai Universal Biotech Co.,Ltd 15921930842 15921930842 yh-wang@univ-bio.com China 25030 58
Zibo Hangyu Biotechnology Development Co., Ltd +86-0533-2185556 +86-15965530500 nickzhang@hangyubiotech.com China 9908 58
1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-[2'-(TRIFLUOROMETHYL)PHENYL]-3-PYRIDINECARBOXYLIC ACID METHYL ESTER 1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-[2-(TRIFLUOROMETHYL)PHENYL]-3-PYRIDINECARBOXYLIC ACID, METHYL ESTER 1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-(2-[TRIFLUOROMETHYL]PHENYL)PYRIDINE-3-CARBOXYLIC ACID METHYL ESTER (+/-)-BAY K 8644 BAY K-8644 (+/-) (+)-(S)-1,4-dihydro-2,6-dimethyl-3-nitro-4-(2-trifluoromethylphenyl)pyridine-5-carboxylic acid (±)-Bay K 8644 - CAS 93468-89-4 - Calbiochem 93468-89-4 BioChemical Biochemicals and Reagents Enzymes, Inhibitors, and Substrates Enzyme Inhibitors by Type Enzyme Inhibitors Substrate Analogs