trans-Aconitic acid
- CAS No.
- 4023-65-8
- Chemical Name:
- trans-Aconitic acid
- Synonyms
- (E)-prop-1-ene-1,2,3-tricarboxylic acid;trans-Aconitate;citridic acid;ACHILLEIC ACID;TRANS-4-METHYLCYCLOHEXYLAMINE;(E)-1-PROPENE-1,2,3-TRICARBOXYLIC ACID;AKOS NCG1-0088;equisetic acid;(E)-Aconitic Acid;traps-Aconitlc acid
- CBNumber:
- CB2476371
- Molecular Formula:
- C6H6O6
- Molecular Weight:
- 174.11
- MDL Number:
- MFCD00002721
- MOL File:
- 4023-65-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 190 °C (dec.)(lit.) |
|---|---|
| Boiling point | 225.05°C (rough estimate) |
| Density | 0.56 g/cm3 (20℃) |
| refractive index | 1.5860 (estimate) |
| FEMA | 2010 | ACONITIC ACID |
| storage temp. | Store below +30°C. |
| solubility | 400g/l |
| pka | 2.8(at 25℃) |
| form | Solid |
| color | White to Off-White |
| Odor | at 100.00 %. vegetable musty nut dry toasted |
| PH | 3.14(1 mM solution);2.48(10 mM solution);1.92(100 mM solution) |
| Odor Type | vegetable |
| Water Solubility | Soluble in water at 20°C 400g/L. Slightly soluble in ether. |
| BRN | 1725830 |
| InChI | 1S/C6H6O6/c7-4(8)1-3(6(11)12)2-5(9)10/h1H,2H2,(H,7,8)(H,9,10)(H,11,12)/b3-1+ |
| InChIKey | GTZCVFVGUGFEME-HNQUOIGGSA-N |
| SMILES | OC(=O)C\C(=C/C(O)=O)C(O)=O |
| LogP | -0.14 |
| CAS DataBase Reference | 4023-65-8(CAS DataBase Reference) |
| FDA UNII | 7DB37960CW |
| EPA Substance Registry System | 1-Propene-1,2,3-tricarboxylic acid, (1E)- (4023-65-8) |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H335-H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P280g-P305+P351+P338 | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 24/25-37/39-36-26 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | UD2380000 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 2917.19.7050 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| REACH Registrations | Inactive | |||||||||
| NFPA 704 |
|
trans-Aconitic acid price More Price(54)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 122750 | trans-Aconitic acid 98% | 4023-65-8 | 25g | $82.6 | 2026-04-30 | Buy |
| Sigma-Aldrich | PHL82257 | trans-Aconitic acid phyproof? Reference Substance | 4023-65-8 | 100MG | $301 | 2026-04-30 | Buy |
| Sigma-Aldrich | 122750 | trans-Aconitic acid 98% | 4023-65-8 | 100g | $237 | 2026-04-30 | Buy |
| TCI Chemical | A0127 | trans-Aconitic Acid >98.0%(HPLC)(T) | 4023-65-8 | 25g | $76 | 2026-04-30 | Buy |
| TCI Chemical | A0127 | trans-Aconitic Acid >98.0%(HPLC)(T) | 4023-65-8 | 500g | $711 | 2026-04-30 | Buy |
trans-Aconitic acid Chemical Properties, Uses, Production
Chemical Properties
WHITE TO OFF-WHITE CRYSTALLINE POWDER
Uses
It plays an important role as an antimicrobial agent that blocks the transformation of Leishmania donovani amastigotes to prostigotes. trans-Aconitic acid is also used in synthesis of aconitate esters. It may be used for cross-linking polyvinyl alcohol film for preparing composite nanofiltration membranes.
Definition
ChEBI: The trans-isomer of aconitic acid.
General Description
trans-Aconitic acid is inhibitor of the tricarboxylic acid cycle and was identified in range grasses.
Biochem/physiol Actions
Antimicrobial agent that blocks the transformation of Leishmania donovani amastigotes to prostigotes.
Purification Methods
Purify trans-acid by dissolving it in AcOH (77g/150mL), filtering and cooling. The acid separates (55g) as colourless needles. A further quantity (10g) can be obtained by reducing the volume of the filtrate. The acid is dried in air then in a vacuum desiccator over NaOH. The acid can be recrystallised from Me2CO/CHCl3. The highest melting point is obtained with the very dry acid. A melting point of 209o was obtained on a Dennis bar [Dennis & Shalton J Am Chem Soc 52 3128 1930, Bruce Org Synth Coll Vol II 12 1943]. [Beilstein 2 IV 2405.]
trans-Aconitic acid Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chongqing Chemieliva Pharmaceutical Co., Ltd. | 18696571988 | amy.lei@chemieliva.com | China | 1350 | 60 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
View Latest Price from trans-Aconitic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-25 | (E)-Aconitic Acid
4023-65-8
|
$3.90-5.90 | 1KG | 99% | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | ||
 |
2026-08-07 | TRANS-ACONITIC ACID
4023-65-8
|
$1.00-2.00 | 1KG | 99% | 100000KG | Shaanxi Dideu Medichem Co. Ltd | |
 |
2026-07-29 | trans-Aconitic acid
4023-65-8
|
$39.00 | 99.16% | 10g | TargetMol Chemicals Inc. |
-
- (E)-Aconitic Acid
4023-65-8
- $3.90-5.90
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-
- TRANS-ACONITIC ACID
4023-65-8
- $1.00-2.00
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-
- trans-Aconitic acid
4023-65-8
- $39.00
- 99.16%
- TargetMol Chemicals Inc.
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