N-Acetic acid-indole-3-carboxaldehyde
- CAS No.
- 138423-98-0
- Chemical Name:
- N-Acetic acid-indole-3-carboxaldehyde
- Synonyms
- TIMTEC-BB SBB010076;CHEMBRDG-BB 4002661;3-FORMYL INDOLEACETIC ACID;3-FORMYLINDOLE-1-ACETIC ACID;3-Formylindole-N-acetic acid;3-Formylindol-1-yl-AceticAci;(3-FORMYL-1-INDOLYL)ACETIC ACID;3-FORMYLINDOLE-1-YL-ACETIC ACID;3-Formyl-1H-indole-1-acetic acid;(3-FORMYL-INDOL-1-YL)-ACETIC ACID
- CBNumber:
- CB2476876
- Molecular Formula:
- C11H9NO3
- Molecular Weight:
- 203.19
- MDL Number:
- MFCD00452923
- MOL File:
- 138423-98-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 197-200 °C(lit.) |
|---|---|
| Boiling point | 458.5±25.0 °C(Predicted) |
| Density | 1.30±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
| pka | 4.15±0.10(Predicted) |
| form | solid |
| Appearance | Light yellow to yellow Solid |
| Sensitive | Air Sensitive |
| BRN | 5431204 |
| InChI | InChI=1S/C11H9NO3/c13-7-8-5-12(6-11(14)15)10-4-2-1-3-9(8)10/h1-5,7H,6H2,(H,14,15) |
| InChIKey | ZUUGBTJTGRTIFK-UHFFFAOYSA-N |
| SMILES | N1(CC(O)=O)C2=C(C=CC=C2)C(C=O)=C1 |
| CAS DataBase Reference | 138423-98-0(CAS DataBase Reference) |
| UNSPSC Code | 12352200 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 8-10-23 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29339900 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
N-Acetic acid-indole-3-carboxaldehyde price More Price(55)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 17028 | (3-Formyl-1-indolyl)acetic acid ≥97.0% | 138423-98-0 | 1g | $74.8 | 2023-06-20 | Buy |
| Biosynth | FF49821 | (3-Formyl-1-indolyl)acetic acid | 138423-98-0 | 25g | $150 | 2026-06-04 | Buy |
| Biosynth | FF49821 | (3-Formyl-1-indolyl)acetic acid | 138423-98-0 | 5g | $150 | 2026-06-04 | Buy |
| Biosynth | FF49821 | (3-Formyl-1-indolyl)acetic acid | 138423-98-0 | 50g | $165.5 | 2026-06-04 | Buy |
| Biosynth | FF49821 | (3-Formyl-1-indolyl)acetic acid | 138423-98-0 | 100g | $292 | 2026-06-04 | Buy |
N-Acetic acid-indole-3-carboxaldehyde Chemical Properties,Uses,Production
Chemical Properties
Solid
Uses
Handle to synthesize an indolecarboxaldehyde resin by coupling to an amino-resin. Amines and derivatives can be immobilized by reductive amination of this aldehyde resin. Mild cleavage with 50% TFA
reaction suitability
reagent type: cross-linking reagent
Synthesis
27065-94-7
138423-98-0
Ethyl (3-formyl-1H-indol-1-yl)acetate (15.9 g, 69 mmol) was dissolved in 1,4-dioxane (100 mL), 1 N sodium hydroxide solution (10 mL) was added, and the resulting mixture was stirred at 0 °C. The reaction mixture was then stirred at room temperature for 4 days. After completion of the reaction, water (500 mL) was added and the mixture was washed with ether (150 mL). The aqueous phase was acidified with 5 N hydrochloric acid to pH < 2 and subsequently extracted with ethyl acetate (250 mL + 150 mL) in two fractions. The organic phases were combined, dried over anhydrous magnesium sulfate, and concentrated under reduced pressure to give (3-formylindol-1-yl)acetic acid (10.3 g, 73% yield) as a white solid. The product was characterized by 1H-NMR (DMSO-d6): δH=5.20 (2H, s), 7.3 (2H, m), 7.55 (1H, d), 8.12 (1H, d), 8.30 (1H, s), 9.95 (1H, s), 13.3 (1H, br s).
References
[1] Patent: WO2006/82245, 2006, A1. Location in patent: Page/Page column 230
[2] Patent: US2005/65066, 2005, A1. Location in patent: Page/Page column 120
[3] Patent: WO2004/80480, 2004, A1. Location in patent: Page/Page column 226
[4] Patent: WO2006/5683, 2006, A1. Location in patent: Page/Page column 225
[5] Patent: US2003/229120, 2003, A1. Location in patent: Page 75
N-Acetic acid-indole-3-carboxaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuhan xinyangruihe Chemical Technology Co., Ltd. | 027-83855316 18171155316 | 3317533608@qq.com | China | 997 | 58 |
| Nantong Herun Biotechnology Co., Ltd | 18362409333 | 18362409333@139.com | China | 4999 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16305 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| XiaoGan ShenYuan ChemPharm co,ltd | 15527621225; 15527621225 | 1791901229@qq.com | China | 6746 | 52 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
View Lastest Price from N-Acetic acid-indole-3-carboxaldehyde manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-03 | N-Acetic acid-indole-3-carboxaldehyde
138423-98-0
|
$1.00 | 1KG | 99% | 100KG | Career Henan Chemical Co |
-
- N-Acetic acid-indole-3-carboxaldehyde
138423-98-0
- $1.00
- 99%
- Career Henan Chemical Co
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