COX (human) Inhibitor Screening Assay Kit
- CAS No.
- Chemical Name:
- COX (human) Inhibitor Screening Assay Kit
- Synonyms
- COX (human) Inhibitor Screening Assay Kit
- CBNumber:
- CB24814441
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
COX (human) Inhibitor Screening Assay Kit price More Price(1)
COX (human) Inhibitor Screening Assay Kit Chemical Properties, Uses, Production
Description
The COX (human) Inhibitor Screening Assay Kit directly measures prostaglandin F2α (PGF2α) by SnCl2 reduction of COX-derived PGH2 produced in the COX reaction. The prostanoid product is quantified via enzyme-linked immunosorbent assay (ELISA) using a broadly specific antiserum that binds to all the major prostaglandin compounds. This assay includes human recombinant COX-1 and COX-2, allowing the user to screen specific inhibitors. It is an excellent tool for general inhibitor screening or for eliminating false positive leads generated by less specific methods.
References
[1] XIAOHONG FAN . Design, synthesis and bioactivity study of N-salicyloyl tryptamine derivatives as multifunctional agents for the treatment of neuroinflammation[J]. European Journal of Medicinal Chemistry, 2020, 193: Article 112217. DOI: 10.1016/j.ejmech.2020.112217
[2] BHUPESH PARASHAR. Inhibition of human neuroblastoma cell growth by CAY10404, a highly selective Cox-2 inhibitor.[J]. Journal of Neuro-Oncology, 2005, 71 2: 141-148. DOI: 10.1007/s11060-004-1721-3
COX (human) Inhibitor Screening Assay Kit Preparation Products And Raw materials
Raw materials
Preparation Products
COX (human) Inhibitor Screening Assay Kit Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Cayman Chemical Company | -- | sales@caymanchem.com | China | 6808 | 58 |
| Langfang Yusheng Ruichuang Technology Co., Ltd. | -- | CHINA | 1857 | 58 | |
| Cayman Chemical Company | -- | cayman@caymanchem.com | United States | 6987 | 81 |
| Supplier | Advantage |
|---|---|
| Cayman Chemical Company | 58 |
| Langfang Yusheng Ruichuang Technology Co., Ltd. | 58 |
| Cayman Chemical Company | 81 |
