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| | COX (human) Inhibitor Screening Assay Kit Basic information |
| | COX (human) Inhibitor Screening Assay Kit Chemical Properties |
| | COX (human) Inhibitor Screening Assay Kit Usage And Synthesis |
| Description | The COX (human) Inhibitor Screening Assay Kit directly measures prostaglandin F2α (PGF2α) by SnCl2 reduction of COX-derived PGH2 produced in the COX reaction. The prostanoid product is quantified via enzyme-linked immunosorbent assay (ELISA) using a broadly specific antiserum that binds to all the major prostaglandin compounds. This assay includes human recombinant COX-1 and COX-2, allowing the user to screen specific inhibitors. It is an excellent tool for general inhibitor screening or for eliminating false positive leads generated by less specific methods. | | References | [1] XIAOHONG FAN . Design, synthesis and bioactivity study of N-salicyloyl tryptamine derivatives as multifunctional agents for the treatment of neuroinflammation[J]. European Journal of Medicinal Chemistry, 2020, 193: Article 112217. DOI: 10.1016/j.ejmech.2020.112217
[2] BHUPESH PARASHAR. Inhibition of human neuroblastoma cell growth by CAY10404, a highly selective Cox-2 inhibitor.[J]. Journal of Neuro-Oncology, 2005, 71 2: 141-148. DOI: 10.1007/s11060-004-1721-3 |
| | COX (human) Inhibitor Screening Assay Kit Preparation Products And Raw materials |
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