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COX (ovine) Colorimetric Inhibitor Screening Assay Kit

CAS No.
Chemical Name:
COX (ovine) Colorimetric Inhibitor Screening Assay Kit
Synonyms
COX (ovine) Colorimetric Inhibitor Screening Assay Kit
CBNumber:
CB54814442
Molecular Formula:
Molecular Weight:
0
MDL Number:
MOL File:
Mol file
Last updated:2025-08-20 16:56:19

COX (ovine) Colorimetric Inhibitor Screening Assay Kit price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 760111 COX (ovine) Colorimetric Inhibitor Screening Assay Kit 192Well $862 2026-04-30 Buy
Product number Packaging Price Buy
760111 192Well $862 Buy

COX (ovine) Colorimetric Inhibitor Screening Assay Kit Chemical Properties, Uses, Production

Description

The COX Colorimetric Inhibitor Screening Assay measures the peroxidase component of cyclooxygenases. The peroxidase activity is assayed colorimetrically by monitoring the appearance of oxidized N,N,N'',N''-tetramethyl-p-phenylenediamine (TMPD) at 590 nm. Inhibition of COX activity, measured by TMPD oxidation, by a variety of selective and nonselective inhibitors, shows changed potencies similar to those observed with other in vitro methods. The COX Colorimetric Inhibitor Screening assay includes both ovine COX-1 and COX-2 enzymes in order to screen isozyme-specific inhibitors. The Cayman COX Colorimetric Assay is a time saving tool for screening vast numbers of inhibitors.

References

[1] AFTAB AHMAD. Ursolic acid rich Ocimum sanctum L leaf extract loaded nanostructured lipid carriers ameliorate adjuvant induced arthritis in rats by inhibition of COX-1, COX-2, TNF-α and IL-1: Pharmacological and docking studies.[J]. ACS Applied Bio Materials, 2018: e0193451. DOI: 10.1371/journal.pone.0193451
[2] NANANG FAKHRUDIN. n-Hexane Insoluble Fraction of Plantago lanceolata Exerts Anti-Inflammatory Activity in Mice by Inhibiting Cyclooxygenase-2 and Reducing Chemokines Levels.[J]. Scientia Pharmaceutica, 2017, 85 1. DOI: 10.3390/scipharm85010012
[3] WEI LI. YAP transcriptionally regulates COX-2 expression and GCCSysm-4 (G-4), a dual YAP/COX-2 inhibitor, overcomes drug resistance in colorectal cancer.[J]. ACS Chemical Biology, 2017: 144. DOI: 10.1186/s13046-017-0612-3
[4] RAJU GAUTAM. Rutin attenuates intestinal toxicity induced by Methotrexate linked with anti-oxidative and anti-inflammatory effects.[J]. BMC Complementary and Alternative Medicine, 2016, 16 1: 99. DOI: 10.1186/s12906-016-1069-1
[5] ARVIND KUMAR GIRI. Effect of lycopene against gastroesophageal reflux disease in experimental animals.[J]. BMC Complementary and Alternative Medicine, 2015: 110. DOI: 10.1186/s12906-015-0631-6
[6] RAQUEL TEIXEIRA FERREIRA. Mechanisms Underlying the Antinociceptive, Antiedematogenic, and Anti-Inflammatory Activity of the Main Flavonoid from Kalanchoe pinnata.[J]. Evidence-based Complementary and Alternative Medicine, 2014, 2014: 429256. DOI: 10.1155/2014/429256
[7] HEINZ FRETZ*. Identification of 2-(2-(1-Naphthoyl)-8-fluoro-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)acetic Acid (Setipiprant/ACT-129968), a Potent, Selective, and Orally Bioavailable Chemoattractant Receptor-Homologous Molecule Expressed on Th2 Cells (CRTH2) Antagonist[J]. Journal of Medicinal Chemistry, 2013, 56 12: 4899-4911. DOI: 10.1021/jm400122f
[8] SEUNG HO LEE. Dual inhibition of cyclooxygenases-2 and 5-lipoxygenase by deoxypodophyllotoxin in mouse bone marrow-derived mast cells.[J]. Biological & pharmaceutical bulletin, 2004, 27 6: 786-788. DOI: 10.1248/bpb.27.786

COX (ovine) Colorimetric Inhibitor Screening Assay Kit Preparation Products And Raw materials

Raw materials

Preparation Products

COX (ovine) Colorimetric Inhibitor Screening Assay Kit Suppliers

Global Suppliers ( 2)
Supplier Tel Email Country ProdList Advantage
Cayman Chemical Company -- sales@caymanchem.com China 6808 58
Cayman Chemical Company -- cayman@caymanchem.com United States 6987 81
COX (ovine) Colorimetric Inhibitor Screening Assay Kit