TOPRAMEZONE
- CAS No.
- 210631-68-8
- Chemical Name:
- TOPRAMEZONE
- Synonyms
- [3-(4,5-Dihydro-3-isoxazolyl)-2-methyl-4-(methylsulfonyl)phenyl](5-hydroxy-1-methyl-1H-pyrazol-4-yl)methanone;Methanone, [3-(4,5-dihydro-3-isoxazolyl)-2-methyl-4-(methylsulfonyl)phenyl](5-hydroxy-1-methyl-1H-pyrazol-4-yl)-;bas 670;Hsdb 7500;opramezone;Impact(TM);TOPRAMEZONE;Pyrthalonil;Topramezone 97%;Topramezone [iso]
- CBNumber:
- CB2501011
- Molecular Formula:
- C16H17N3O5S
- Molecular Weight:
- 363.39
- MDL Number:
- MFCD09953760
- MOL File:
- 210631-68-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Topramezone PESTANAL | 34225 | 100mg | $445 |
| Topramezone >95%(HPLC) | TRC-T542513-250MG | 250mg | $683 |
| Topramezone >95%(HPLC) | TRC-T542513-100MG | 100mg | $362 |
| Topramezone | FT172758 | 5mg | $900 |
| Topramezone | FT172758 | 2mg | $900 |
| More product size | |||
| Boiling point | 590.5±60.0 °C(Predicted) |
|---|---|
| Density | 1.49±0.1 g/cm3(Predicted) |
| solubility | Chloroform (Slightly, Heated), Water (Slightly, Heated) |
| pka | 6.35±0.50(Predicted) |
| form | Solid |
| color | Light yellow to yellow |
| Henry's Law Constant | 1.0×1012 mol/(m3Pa) at 25℃, HSDB (2015) |
| Major Application |
agriculture environmental |
| InChI | InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,21H,6-7H2,1-3H3 |
| InChIKey | IYMLUHWAJFXAQP-UHFFFAOYSA-N |
| SMILES | C(C1=CC=C(S(C)(=O)=O)C(C2CCON=2)=C1C)(C1=C(O)N(C)N=C1)=O |
| LogP | 0.957 (est) |
| FDA UNII | W4934JAQ65 |
| EPA Substance Registry System | Methanone, [3-(4,5-dihydro-3-isoxazolyl)-2-methyl-4-(methylsulfonyl)phenyl](5-hydroxy-1-methyl-1H-pyrazol-4-yl)- (210631-68-8) |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS08,GHS09 |
|---|---|
| Signal word | Danger |
| Hazard statements | H360D-H410 |
| Precautionary statements | P202-P273-P280-P308+P313-P391-P405 |
| PPE | Eyeshields, Gloves, type P3 (EN 143) respirator cartridges |
| Hazard Codes | T,N |
| Risk Statements | 61-50/53 |
| Safety Statements | 53-45-60-61 |
| RIDADR | UN3077 9/PG 3 |
| WGK Germany | 1 |
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
| Hazard Classifications | Aquatic Acute 1 Aquatic Chronic 1 Repr. 1B |
| Hazardous Substances Data | 210631-68-8(Hazardous Substances Data) |
TOPRAMEZONE price More Price(15)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 34225 | Topramezone PESTANAL | 210631-68-8 | 100mg | $445 | 2026-04-30 | Buy |
| TRC | TRC-T542513-250MG | Topramezone >95%(HPLC) | 210631-68-8 | 250mg | $683 | 2026-06-03 | Buy |
| TRC | TRC-T542513-100MG | Topramezone >95%(HPLC) | 210631-68-8 | 100mg | $362 | 2026-06-03 | Buy |
| Biosynth | FT172758 | Topramezone | 210631-68-8 | 5mg | $900 | 2026-06-04 | Buy |
| Biosynth | FT172758 | Topramezone | 210631-68-8 | 2mg | $900 | 2026-06-04 | Buy |
TOPRAMEZONE Chemical Properties,Uses,Production
Description
Topramezone is a highly flexible post-emergent herbicide that's safe for use on all field and specialty maize regardless of trait.
Uses
Topramezone is a herbicide that belongs to the class of pyrazolones or benzoylpyrazoles. It can be used to control broad leaved weeds and grass weeds in maize crop protection.
Definition
ChEBI: An aromatic ketone that is phenyl 1H-pyrazol-4-yl ketone in which the pyrazolyl group is substituted at positions 1 and 5 by methyl and hydroxy groups, respectively, and in which the phenyl group is substituted at positions 2, 3, and 4 b methyl, 4,5-dihydro-1,2-oxazol-3-yl, and methylsulfonyl groups, respectively. A potent inhibitor of 4-hydroxyphenylpyruvate dioxygenase (HPPD) that is rapily metabolised by corn to non-active substances, it is used as a herbicide for the treatment of broa leaf weeds.
Production Methods
The industrial synthesis of topramezone begins with the construction of a pyrazolone ring, typically formed by condensing hydrazine derivatives with beta-keto esters. This intermediate is then coupled with a benzoyl chloride derivative containing a methylsulfonyl group and a dihydroisoxazole moiety, which are essential for herbicidal activity. The reaction sequence involves acylation, sulfonation, and heterocyclic ring formation under controlled conditions, often using polar aprotic solvents and acid or base catalysts
Mechanism of action
Systemic, highly selective, rapidly absorbed and translocated. Bleaching: inhibition of 4-hydroxyphenyl-pyruvate-dioxygenase.
Pesticide Type
Herbicide
TOPRAMEZONE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Huizhili (Changzhou) Life Technology Co., Ltd | 13906110102 | 13906110102@139.com | China | 16 | 58 |
| Hebei Conchain Biotech Co.,Ltd | +86-13630830762 +86-13630830762 | 2415217937@qq.com | China | 135 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1059@dideu.com | China | 29096 | 58 |
| Hebei Xinsheng New Material Technology Co., LTD. | +86-16632316109 | xinshengkeji@xsmaterial.com | China | 1082 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81139210 +86-17392587031 | 1059@dideu.com | China | 9984 | 58 |
| Finetech Industry Limited | +86-27-8746-5837 +86-18627785180 | info@finetechnology-ind.com | China | 9539 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +86-18949823763 | sales@tnjchem.com | China | 25333 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +86-571-86217390; +8618058761490 | info@gihichemicals.com | China | 49859 | 58 |
| SUZHOU SENFEIDA CHEMICAL CO.,LTD | +86-0512-83500002 +86-15195660023 | 3899766280@qq.com | China | 26349 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +86-18327326525 | masar@topule.com | China | 8433 | 58 |
View Lastest Price from TOPRAMEZONE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-12-25 | Topramezone
210631-68-8
|
25kg | 99% | Huizhili (Changzhou) Life Technology Co., Ltd | |||
 |
2025-11-18 | TOPRAMEZONE
210631-68-8
|
$1.10 | 1g | 99.9% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2023-11-14 | TOPRAMEZONE
210631-68-8
|
$25.00-35.00 | 1kg | 99% | 20 Ton | Hebei Xinsheng New Material Technology Co., LTD. |
-
- Topramezone
210631-68-8
- $0.00
- 99%
- Huizhili (Changzhou) Life Technology Co., Ltd
-
- TOPRAMEZONE
210631-68-8
- $1.10
- 99.9%
- Dideu Industries Group Limited
-
- TOPRAMEZONE
210631-68-8
- $25.00-35.00
- 99%
- Hebei Xinsheng New Material Technology Co., LTD.
