ChemicalBook >> CAS DataBase List >>N,N'-Dimethylpiperazine

N,N'-Dimethylpiperazine

CAS No.
106-58-1
Chemical Name:
N,N'-Dimethylpiperazine
Synonyms
1,4-DIMETHYLPIPERAZINE;N,N-DIMETHYLPIPERAZINE;Piperazine, 1,4-dimethyl-;Lupetazine;texacatdmp;Texacat DMP;LUPRAGEN(R) N 204;N,N'-Dimethylpiperaz;Zopiclone Impurity 14;N'-Dimethylpiperazine
CBNumber:
CB2664286
Molecular Formula:
C6H14N2
Molecular Weight:
114.19
MDL Number:
MFCD00006156
MOL File:
106-58-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 00:48:51

N,N'-Dimethylpiperazine Properties

Melting point -1 °C
Boiling point 131-132 °C750 mm Hg(lit.)
Density 0.844 g/mL at 25 °C(lit.)
vapor pressure 20 hPa (20 °C)
refractive index n20/D 1.4463(lit.)
Flash point 65 °F
storage temp. Store below +30°C.
solubility miscible
pka pK1:4.630(+2);pK2:8.539(+1) (25°C)
form Liquid
Specific Gravity 0.844
color Clear colorless to yellow
PH 11.4 (H2O)
explosive limit 1.8-9.6%(V)
Viscosity 0.883mm2/s
Water Solubility miscible
BRN 103022
Henry's Law Constant 2.0×102 mol/(m3Pa) at 25℃, Nguyen (2013)
InChI 1S/C6H14N2/c1-7-3-5-8(2)6-4-7/h3-6H2,1-2H3
InChIKey RXYPXQSKLGGKOL-UHFFFAOYSA-N
SMILES CN1CCN(C)CC1
LogP -0.26 at 20℃
CAS DataBase Reference 106-58-1(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII TF146U602L
NIST Chemistry Reference Piperazine, 1,4-dimethyl-(106-58-1)
EPA Substance Registry System Piperazine, 1,4-dimethyl- (106-58-1)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)Corrosion (GHS05)
GHS02,GHS05
Signal word  Danger
Hazard statements  H314-H225
Precautionary statements  P501-P240-P210-P233-P243-P241-P242-P264-P280-P370+P378-P303+P361+P353-P301+P330+P331-P363-P304+P340+P310-P305+P351+P338+P310-P403+P235-P405
PPE Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Hazard Codes  F,C
Risk Statements  11-34-22-10
Safety Statements  16-26-27-36/37/39-45-25-23
RIDADR  UN 2924 3/PG 2
WGK Germany  1
RTECS  TL5945000
Autoignition Temperature 180 °C
TSCA  TSCA listed
HazardClass  3
PackingGroup  II
HS Code  29335995
Storage Class 3 - Flammable liquids
Hazard Classifications Acute Tox. 4 Oral
Eye Dam. 1
Flam. Liq. 2
Skin Corr. 1C
Toxicity LD50 orally in Rabbit: 2800 mg/kg LD50 dermal Rabbit 3000 mg/kg
REACH Registrations Active
Limited Quantities 1.0 L (0.3 gallon) (liquid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)
NFPA 704
4
3 0

N,N'-Dimethylpiperazine price More Price(32)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich D179302 1,4-Dimethylpiperazine 98% 106-58-1 5g $40 2026-04-30 Buy
Sigma-Aldrich D179302 1,4-Dimethylpiperazine 98% 106-58-1 100g $85.6 2026-04-30 Buy
Sigma-Aldrich 8.03580 1,4-Dimethylpiperazine for synthesis 106-58-1 100mL $40.7 2026-04-30 Buy
TCI Chemical D0787 N,N'-Dimethylpiperazine >98.0%(GC)(T) 106-58-1 25mL $21 2026-04-30 Buy
TCI Chemical D0787 N,N'-Dimethylpiperazine >98.0%(GC)(T) 106-58-1 500mL $130 2026-04-30 Buy
Product number Packaging Price Buy
D179302 5g $40 Buy
D179302 100g $85.6 Buy
8.03580 100mL $40.7 Buy
D0787 25mL $21 Buy
D0787 500mL $130 Buy

N,N'-Dimethylpiperazine Chemical Properties,Uses,Production

Chemical Properties

clear colorless to yellow liquid

Uses

Catalyst for polyurethane foams and intermediate for cationic surfactants.

Preparation

N,N'-Dimethylpiperazine is obtained from piperazine and methanol or formaldehyde under aminating conditions.

Synthesis Reference(s)

Canadian Journal of Chemistry, 63, p. 725, 1985 DOI: 10.1139/v85-120

Flammability and Explosibility

Flammable

110-85-0
50-00-0
106-58-1
Synthesis of N,N'-Dimethylpiperazine from Piperazine and Formaldehyde
Global( 289)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Boyle Chemical Co., Ltd. 021-50182298 021-50180596 sales@boylechem.com China 2202 55
Tianjin Zhongxin Chemtech Co., Ltd. 022-66880623 sales@tjzxchem.com China 612 60
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Beijing dtftchem Technology Co., Ltd. 010-60275820 13031183356 elainezt@sina.com China 1386 62
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
JinYan Chemicals(ShangHai) Co.,Ltd. 13817811078 sales@jingyan-chemical.com China 9963 60
Jia Xing Isenchem Co.,Ltd 0573-85285100 18627885956 isenchem@163.com China 9389 66

View Lastest Price from N,N'-Dimethylpiperazine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N,N'-Dimethylpiperazine pictures 2026-09-11 N,N'-Dimethylpiperazine
106-58-1
$5.00 1KG ≥99% 500mt/year Jinan Finer Chemical Co., Ltd
N,N'-Dimethylpiperazine  pictures 2026-08-20 N,N'-Dimethylpiperazine
106-58-1
$1.10 1g 99.00% 100 Tons Dideu Industries Group Limited
N,N'-Dimethylpiperazine pictures 2026-03-20 N,N'-Dimethylpiperazine
106-58-1
$10.00 1KG 99% 100 mt Hebei Chuanghai Biotechnology Co., Ltd
N,N'-Dimethylpiperaz N,N'-Dimethylpiperazine, 98.5% Lupragen N204 (Dimethylpiperizine) 1,4-DIMETHYLPIPERAZINE FOR SYNTHESIS 1,4- two- Methyl piperazine N,N-Dimethylpiperazine Dihydrochloride N,N'-Dimethyl piperazine 1,4-Dimethylpiperazine N, N- two methylpiperazine N'-Dimethylpiperazine Zopiclone Impurity 14 1,4-dimethyl-piperazin Lupetazine N,N'-Dimethyipiperazine Texacat DMP texacatdmp LUPRAGEN(R) N 204 Trans-1,4-Dimethylpiperazine N,N'-Dimethylpiperazine, 98.50% Piperazine, 1,4-dimethyl- N,N'-Dimethylpiperazine > Diethylcarbamazine EP Impurity B N,N'-Dimethylpiperazine ISO 9001:2015 REACH Diethylcarbamazine citrate EP Impurity B N,N'-Dimethylpiperazine 1,4-DIMETHYLPIPERAZINE N,N-DIMETHYLPIPERAZINE 106-58-1 104-58-1 Piperazines Heterocyclic Building Blocks Building Blocks Building Blocks C4 to C8 Chemical Synthesis Heterocyclic Building Blocks Building Blocks Heterocyclic Building Blocks Piperazines Piperidines, Piperidones, Piperazines Piperaizine Piperazine derivates