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2,4-Dimethyl-5-nitroaniline

2,4-Dimethyl-5-nitroaniline Structure
2,4-Dimethyl-5-nitroaniline structure
CAS No.
2124-47-2
Chemical Name:
2,4-Dimethyl-5-nitroaniline
Synonyms
5-Nitro-2,4-xylidine;2,4-Dimethyl-5-nitro-anilin;5-nitro-2,4-dimethylaniline;2,4-Dimethyl-5-nitroaniline;(2,4-dimethyl-5-nitrophenyl)am;2,4-dimethyl-5-nitrobenzenamine;5-Amino-2,4-dimethylnitrobenzene;(2,4-dimethyl-5-nitrophenyl)amine;Benzenamine, 2,4-dimethyl-5-nitro-;4-Amino-1,3-dimethyl-6-nitrobenzene
CBNumber:
CB2681483
Molecular Formula:
C8H10N2O2
Molecular Weight:
166.18
MDL Number:
MFCD00025199
MOL File:
2124-47-2.mol
MSDS File:
SDS
Last updated:2026-09-12 18:51:23
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2,4-Dimethyl-5-nitroaniline Properties

Melting point 122.0 to 126.0 °C
Boiling point 329.4±37.0 °C(Predicted)
Density 1.220±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
form powder to crystal
pka 2.83±0.10(Predicted)
color Light yellow to Brown

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319
Precautionary statements  P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330
Hazard Codes  Xi
HazardClass  IRRITANT
HS Code  2921420090
NFPA 704
0
2 0

2,4-Dimethyl-5-nitroaniline price More Price(48)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S740365 2,4-DIMETHYL-5-NITROANILINE AldrichCPR 2124-47-2 1 unit $32.7 2026-04-30 Buy
Sigma-Aldrich S740365 2,4-DIMETHYL-5-NITROANILINE Aldrich 2124-47-2 50mg $29.8 2024-03-01 Buy
TCI Chemical D5196 2,4-Dimethyl-5-nitroaniline >98.0%(GC)(T) 2124-47-2 1g $70 2026-04-30 Buy
TCI Chemical D5196 2,4-Dimethyl-5-nitroaniline >98.0%(GC)(T) 2124-47-2 5g $207 2026-04-30 Buy
Activate Scientific AS49010 2,4-Dimethyl-5-nitroaniline 97% 2124-47-2 1g $25 2026-06-04 Buy
Product number Packaging Price Buy
S740365 1 unit $32.7 Buy
S740365 50mg $29.8 Buy
D5196 1g $70 Buy
D5196 5g $207 Buy
AS49010 1g $25 Buy

2,4-Dimethyl-5-nitroaniline Chemical Properties, Uses, Production

Uses

2,4-Dimethyl-5-nitroaniline is a reagent that is used in the synthesis of symmetric dinitro/tetranitro-functionalized Troger''s bases via heterocyclization of nitroanilines/dinitroanilines with diglycolic acid or paraformaldehyde.

Synthesis

2,4-Dimethyl aniline

95-68-1

2,4-DIMETHYL-5-NITROANILINE

2124-47-2

The general procedure for the synthesis of 2,4-dimethyl-5-nitroaniline from 2,4-dimethylaniline is as follows: nitric acid (33 g) was added slowly and dropwise to a stirring solution of 2,4-dimethylaniline (40 g, 0.33 mmol) in concentrated hydrochloric acid over a period of 3 h, keeping the reaction temperature below 15 °C. The reaction temperature was kept below 15 °C for the first time. Subsequently, sulfuric acid (400 g) was added. After addition, the reaction mixture was continued to be stirred at 15 °C for 1 h. The reaction was then poured into ice (600 mL), stirred for 30 min and filtered. The resulting yellow filter cake was neutralized with saturated aqueous sodium bicarbonate (500 mL) and subsequently extracted with ethyl acetate (3 x 200 mL). The organic extracts were combined, dried with magnesium sulfate, filtered and the solvent was removed in vacuum to give the crude product. The crude product was recrystallized by ethanol-water mixed solvent to give a final orange solid product (39 g, 71% yield, containing 20% dinitro by-product). The product was analyzed by IR showing characteristic absorption peaks (Nujol, cm-1): 3469, 3386, 3239, 2956, 2925, 2855, 1719, 1636, 1514, 1461, 1377, 1339, 1297, 1273, 1222, 1170, 1034, 992, 885, 870, 849. 805, 758, 745, 723, 640, 607 and 571; 1H NMR (400 MHz, CDCl3) δ: 7.15 (1H, s), 6.87 (1H, s), 4.99 (2H, br.s), 2.21 (3H, s), 1.97 (3H, s).

References

[1] European Journal of Organic Chemistry, 2009, # 5, p. 687 - 698
[2] Bioorganic and Medicinal Chemistry, 2016, vol. 24, # 3, p. 403 - 427
[3] Patent: EP1147110, 2003, B1
[4] Chemische Berichte, 1884, vol. 17, p. 265
[5] Journal of the Chemical Society, 1921, vol. 119, p. 718

2,4-Dimethyl-5-nitroaniline synthesis

62476-60-2
2124-47-2
Synthesis of 2,4-Dimethyl-5-nitroaniline from N-(2,4-dimethyl-5-nitrophenyl)acetamide

2,4-Dimethyl-5-nitroaniline Preparation Products And Raw materials

Raw materials

N-(2,4-dimethyl-5-nitrophenyl)acetamide 4,6-Dinitro-1,3-xylene Nitric acid Sulfuric acid Hydrochloric acid
2,4-Dimethyl aniline

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Preparation Products

2,4-Dimethyl-3-nitroaniline 1-Bromo-2,4-dimethyl-5-nitrobenzene fast red RBE base Benzenamine, 5-iodo-2,4-dimethyl-

2,4-Dimethyl-5-nitroaniline Suppliers

Global Suppliers ( 142)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Adamas Reagent, Ltd. 400-6009262 15618770481 yhx@titansci.com China 14098 59
Shanghai Longsheng chemical Co.,Ltd. 58099637 13585536065 sales@shlschem.com China 9880 59
TOKYO CHEMICAL INDUSTRY CO., LTD. 03-36680489 Sales-JP@TCIchemicals.com Japan 28364 80
TCI Europe 320-37350700 sales@tcieurope.eu Europe 23654 75
TCI AMERICA 800-4238616 sales@tciamerica.com Americas 23636 75
9ding chemical ( Shanghai) Limited 4009209199 sales@9dingchem.com China 18201 56
Shanghai Witofly Chemical Co.,Ltd sales@witofly.com China 2853 52
Shanghai Raise Chemical Technology Co.,Ltd +86-021-50935922 China 7854 55
Shanghai Chainpharm Bio-medical Technology Co., Ltd. +86-021-61727342 13611721451 sales@chainpharm.com China 984 58
Supplier Advantage
J & K SCIENTIFIC LTD. 76
Adamas Reagent, Ltd. 59
Shanghai Longsheng chemical Co.,Ltd. 59
TOKYO CHEMICAL INDUSTRY CO., LTD. 80
TCI Europe 75
TCI AMERICA 75
9ding chemical ( Shanghai) Limited 56
Shanghai Witofly Chemical Co.,Ltd 52
Shanghai Raise Chemical Technology Co.,Ltd 55
Shanghai Chainpharm Bio-medical Technology Co., Ltd. 58

View Latest Price from 2,4-Dimethyl-5-nitroaniline manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,4-DIMETHYL-5-NITROANILINE pictures 2026-09-02 2,4-DIMETHYL-5-NITROANILINE
2124-47-2
 $1.00-101.00 1KG 99% Henan Fengda Chemical Co., Ltd
2,4-DIMETHYL-5-NITROANILINE pictures 2026-07-08 2,4-DIMETHYL-5-NITROANILINE
2124-47-2
 1KG 98% 1000kg Shaanxi Dideu New Materials Co. Ltd
2,4-Dimethyl-5-nitro-anilin pictures 2022-01-15 2,4-Dimethyl-5-nitro-anilin
2124-47-2
 1KG 99.2% 100 tons Honest Joy Holdings Limited

2124-47-2 (2,4-Dimethyl-5-nitroaniline) Related Search:

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2,4-DIMETHYL-5-NITROANILINE 2,4-Dimethyl-5-nitro-anilin 2,4-dimethyl-5-nitrobenzenamine 5-Amino-2,4-dimethylnitrobenzene (2,4-dimethyl-5-nitrophenyl)amine 4-Amino-1,3-dimethyl-6-nitrobenzene 5-Amino-2,4-dimethylnitrobenzene, 5-Nitro-2,4-xylidine Benzenamine, 2,4-dimethyl-5-nitro- 2,4-Dimethyl-5-Nitroaniline(WXC01839) 5-nitro-2,4-dimethylaniline (2,4-dimethyl-5-nitrophenyl)am 2,4-DIMETHYL-5-NITROANILINE ISO 9001：2015 REACH 5-Nitro-2,4-xylidine 2,4-Dimethyl-5-nitroaniline 2124-47-2