6-Bromo-3-isopropyl-[1,2,4]triazolo[4,3-a]pyridine
![6-Bromo-3-isopropyl-[1,2,4]triazolo[4,3-a]pyridine Structure](CAS/GIF/459448-06-7.gif)
- CAS No.
- 459448-06-7
- Chemical Name:
- 6-Bromo-3-isopropyl-[1,2,4]triazolo[4,3-a]pyridine
- Synonyms
- 6-Bromo-3-isopropyl-[1,2,4]triazolo[4,3-a]pyridine;6-Bromo-3-(propan-2-yl)-[1,2,4]triazolo[4,3-a]pyridine;6-bromo-3-(1-methylethyl)-1,2,4-Triazolo[4,3-a]pyridine;1,2,4-Triazolo[4,3-a]pyridine, 6-bromo-3-(1-methylethyl)-
- CBNumber:
- CB2737883
- Molecular Formula:
- C9H10BrN3
- Molecular Weight:
- 240.1
- MDL Number:
- MFCD08272050
- MOL File:
- 459448-06-7.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
6-Bromo-3-isopropyl-[1,2,4]triazolo[4,3-a]pyridine price More Price(21)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| aablocks | AA00DALK | 6-Bromo-3-isopropyl-[1,2,4]triazolo[4,3-a]pyridine 97% | 459448-06-7 | 100mg | $19 | 2026-05-28 | Buy |
| aablocks | AA00DALK | 6-Bromo-3-isopropyl-[1,2,4]triazolo[4,3-a]pyridine 97% | 459448-06-7 | 250mg | $30 | 2026-05-28 | Buy |
| aablocks | AA00DALK | 6-Bromo-3-isopropyl-[1,2,4]triazolo[4,3-a]pyridine 97% | 459448-06-7 | 1g | $76 | 2026-05-28 | Buy |
| aablocks | AA00DALK | 6-Bromo-3-isopropyl-[1,2,4]triazolo[4,3-a]pyridine 98% | 459448-06-7 | 5g | $335 | 2026-05-28 | Buy |
| aablocks | AA00DALK | 6-Bromo-3-isopropyl-[1,2,4]triazolo[4,3-a]pyridine 98% | 459448-06-7 | 10g | $602 | 2026-05-28 | Buy |
6-Bromo-3-isopropyl-[1,2,4]triazolo[4,3-a]pyridine Chemical Properties,Uses,Production
Synthesis
77992-44-0
79-30-1
![6-BROMO-3-ISOPROPYL-[1,2,4]TRIAZOLO[4,3-A]PYRIDINE](/CAS/GIF/459448-06-7.gif)
459448-06-7
A mixture of 2-hydrazino-5-bromopyridine (4.34 g, 23.1 mmol) and isobutyryl chloride (21.8 mL, 0.208 mol) was refluxed under mild conditions for 3 hours. After the reaction was completed, the mixture was cooled to room temperature. Hexane (22.0 mL) was added and the resulting slurry was stirred at room temperature for 15 minutes, followed by filtration. The filter cake was washed three times (3×) with hexane and dried in a vacuum oven at 30-35 °C for 48 h to give an off-white powdery product (5.90 g, 92.3% yield). The resulting product (5.87 g, 21.2 mmol) was cooled to 5-10 °C with a two-phase mixture formed with water (12.0 mL) and dichloromethane (18.0 mL). An aqueous NaOH solution (21.5 mL) was added dropwise over 10 min. The reaction mixture was stirred in an ice-water bath for 15 min, followed by separation of the organic layer. The aqueous layer was extracted twice (2×) with dichloromethane. The combined organic extracts were washed with 1:1 brine and dried with anhydrous magnesium sulfate (MgSO). After removing most of the dichloromethane under reduced pressure, ethyl acetate (8.0 mL) was added. When about half of the solvent was evaporated, hexane (32.0 mL) was added. The slurry was stirred in an ice-water bath for 2 hours and subsequently filtered. The filter cake was washed three times (3×) with a 9:1 hexane-ethyl acetate mixture and dried in a vacuum oven at 30-35 °C for 18 h. The final product was 6-bromo-3-isopropyl-[1,2,4]triazolo[4,3-a]pyridine as a tan powder (4.72 g, 92.5% yield).
References
[1] Patent: WO2004/20440, 2004, A1. Location in patent: Page 46
[2] Patent: WO2004/20440, 2004, A1. Location in patent: Page 55
6-Bromo-3-isopropyl-[1,2,4]triazolo[4,3-a]pyridine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Topbiochem Technology Co., Ltd | 021-58170097 | info@topbiochem.com | China | 9513 | 58 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Shanghai Worldyang Chemical Co.,Ltd. | 021-56795766 | sales@worldyachem.com | China | 9475 | 58 |
| Shanghai YuLue Chemical Co., Ltd. | 021-60345187 13671753212 | lzz841106@aliyun.com | China | 10244 | 55 |
| Tianjin Anhao Biological Technology Co., Ltd. | sales@ahpharmatech.com | China | 5734 | 55 | |
| Shanghai XR Chemical Technology Co., Ltd. | 021-31007982 18019432809; | info@xrpharma.com | China | 694 | 55 |
| Zhengzhou Guancheng Laboratory equipment Sales | 0371-88888888 qq272369594;2159423853qq | 2723695949@qq.com | China | 4991 | 50 |
| Zhengzhou Alfachem Co., Ltd. | 0371-53765687 18937137882 | 3969243885@qq.com | China | 7734 | 55 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
View Lastest Price from 6-Bromo-3-isopropyl-[1,2,4]triazolo[4,3-a]pyridine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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![6-Bromo-3-isopropyl-[1,2,4]triazolo[4,3-a]pyridine pictures](/ProductImageEN/2022-09/Small/012a23f3-1490-47ac-b0a6-4d3ed172cc7a.gif) |
2022-09-13 | 6-Bromo-3-isopropyl-[1,2,4]triazolo[4,3-a]pyridine
459448-06-7
|
1G | 98%min | 50kg/month | Shanghai Rlavie Technology Co ltd |
-
- 6-Bromo-3-isopropyl-[1,2,4]triazolo[4,3-a]pyridine
459448-06-7
- 98%min
- Shanghai Rlavie Technology Co ltd
