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6-Bromo-1,2,4-triazolo[4,3-1]pyridine

6-Bromo-1,2,4-triazolo[4,3-1]pyridine structure

CAS No.: 108281-79-4

Chemical Name:: 6-Bromo-1,2,4-triazolo[4,3-1]pyridine

Synonyms: 6-BROMO-[1,2,4]TRIAZOLO[4,3-A]PYRIDINE;6-Bromo[1,2,4]triazolo[4,...;6-BROMO-TRIAZOLO[4,3-A]PYRIDINE;6-Bromo-1,2,4-triazolo[4,3-1]pyridine;1,2,4-Triazolo[4,3-a]pyridine, 6-bromo-;6-Bromo-[1,2,4]triazolo[4,3-a]pyridine 98%;6-Bromo-[1,2,4]triazolo[4,3-a]pyridine;6-BROMO-1,2,4-TRIAZOLO[4,3-1]PYRIDINE ISO 9001：2015 REACH

CBNumber:: CB4840875

Molecular Formula:: C6H4BrN3

Molecular Weight:: 198.02

MDL Number:: MFCD08689506

MOL File:: 108281-79-4.mol

MSDS File:: SDS

Last updated:2026-09-12 18:53:01

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6-Bromo-1,2,4-triazolo[4,3-1]pyridine Properties

Melting point	151-153
Density	1.89±0.1 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
pka	2.38±0.50(Predicted)
form	Solid
Appearance	Light yellow to green yellow Solid
InChI	InChI=1S/C6H4BrN3/c7-5-1-2-6-9-8-4-10(6)3-5/h1-4H
InChIKey	PFKZKSHKBBUZKU-UHFFFAOYSA-N
SMILES	C12=NN=CN1C=C(Br)C=C2
UNSPSC Code	12352200
NACRES	NA.21

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302
Precautionary statements	P280-P305+P351+P338
Hazard Codes	Xi,Xn
Risk Statements	22
WGK Germany	3
Hazard Note	Harmful/Irritant/Keep Cold
HS Code	2933998090
Storage Class	11 - Combustible Solids
Hazard Classifications	Acute Tox. 4 Oral

6-Bromo-1,2,4-triazolo[4,3-1]pyridine price More Price(47)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	SYX00142	6-Bromo-[1,2,4]triazolo[4,3-a]pyridine Aldrich	108281-79-4	1g	$352	2026-04-30	Buy
Apolloscientific	OR3548	6-Bromo-[1,2,4]triazolo[4,3-a]pyridine 98%	108281-79-4	250mg	$21	2026-06-04	Buy
Apolloscientific	OR3548	6-Bromo-[1,2,4]triazolo[4,3-a]pyridine 98%	108281-79-4	500mg	$30	2026-06-04	Buy
Matrix Scientific	069763	6-Bromo-[1,2,4]triazolo[4,3-a]pyridine	108281-79-4	1.00g	$416	2026-05-18	Buy
Matrix Scientific	069763	6-Bromo-[1,2,4]triazolo[4,3-a]pyridine	108281-79-4	5.00g	$1536	2026-05-18	Buy

Product number	Packaging	Price	Buy
SYX00142	1g	$352	Buy
OR3548	250mg	$21	Buy
OR3548	500mg	$30	Buy
069763	1.00g	$416	Buy
069763	5.00g	$1536	Buy

6-Bromo-1,2,4-triazolo[4,3-1]pyridine Chemical Properties, Uses, Production

Synthesis

77992-44-0

122-51-0

108281-79-4

General procedure for the synthesis of 6-bromo-1,2,4-triazolo[4,3-1]pyridine from 2-hydrazino-5-bromopyridine and triethyl orthoformate: to a solution of 5-bromo-2-hydrazinopyridine (7.87 g, 42 mmol) in 200 mL of diethoxymethoxyethane was added p-toluenesulfonic acid (0.30 g, 1.7 mmol), the mixture was heated to 110 °C and stirred for 20 hours. After completion of the reaction, the mixture was cooled to room temperature and concentrated under vacuum. The residue was diluted with 150 mL of water, washed with saturated aqueous NaHCO3 (40 mL), and extracted with dichloromethane (300 mL × 3). The organic phases were combined, dried with anhydrous Na2SO4, and concentrated under vacuum. Purification of the residue by fast silica gel chromatography (petroleum ether/ethyl acetate, v/v = 2/1) afforded 6-bromo-1,2,4-triazolo[4,3-1]pyridine as a yellow solid (6.60 g, 79.77% yield). Mass spectrum (ESI, cation mode) m/z: 197.9 [M + H]+; 1H NMR (600 MHz, CDCl3): δ 8.82 (s, 1H), 8.34 (s, 1H), 7.75 (d, J = 9.7 Hz, 1H), 7.36 (d, J = 9.7 Hz, 1H).

References

[1] Patent: US2014/134133, 2014, A1. Location in patent: Paragraph 0451

6-Bromo-1,2,4-triazolo[4,3-1]pyridine Preparation Products And Raw materials

Raw materials

5-Bromo-2-hydrazinopyridine Triethyl orthoformate

Preparation Products

6-Bromo-1,2,4-triazolo[4,3-1]pyridine Suppliers

Global Suppliers ( 142)

Supplier	Tel	Email	Country	ProdList	Advantage
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61
Wuhan Chemwish Technology Co., Ltd	86-027-67849912	sales@chemwish.com	China	35884	56
Pure Chemistry Scientific Inc.	001-857-928-2050 or 1-888-588-9418	sales@chemreagents.com	United States	10174	62
Nanjing Chemlin Chemical Co., Ltd	025-83697070 13770331960	info@chemlin.com.cn	China	16305	64
Shanghai Ennopharm Co., Ltd.	+86 (21) 6435-5022		China	4263	65
SpringPharma Tech Co.,Ltd	+86-25-68710855, +86-25-68710897	sales@springpharma.net	China	1260	62
Wuhan ariel chemical Co., LTD.	18986259541 18986259541	sales@3stc.com	China	3829	58
Shanghai Topbiochem Technology Co., Ltd	+86-21-60341587	sales@topbiochem.com	China	6166	58
Nanjing Norris-Pharm Technology Co., Ltd	13901585132	sales@norris-pharm.com	China	8869	55

Supplier	Advantage
J & K SCIENTIFIC LTD.	76
Energy Chemical	61
Wuhan Chemwish Technology Co., Ltd	56
Pure Chemistry Scientific Inc.	62
Nanjing Chemlin Chemical Co., Ltd	64
Shanghai Ennopharm Co., Ltd.	65
SpringPharma Tech Co.,Ltd	62
Wuhan ariel chemical Co., LTD.	58
Shanghai Topbiochem Technology Co., Ltd	58
Nanjing Norris-Pharm Technology Co., Ltd	55

View Latest Price from 6-Bromo-1,2,4-triazolo[4,3-1]pyridine manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-08-20	6-BROMO-1,2,4-TRIAZOLO[4,3-1]PYRIDINE 108281-79-4	$1.10	1g	99.00%	100 Tons Min	Dideu Industries Group Limited
	2019-07-11	6-BROMO-1,2,4-TRIAZOLO[4,3-1]PYRIDINE 108281-79-4	$1.00	1KG	99%	1ton	Career Henan Chemical Co

6-BROMO-1,2,4-TRIAZOLO[4,3-1]PYRIDINE
108281-79-4
$1.10
99.00%
Dideu Industries Group Limited

6-BROMO-1,2,4-TRIAZOLO[4,3-1]PYRIDINE
108281-79-4
$1.00
99%
Career Henan Chemical Co

6-Bromo-1,2,4-triazolo[4,3-1]pyridine Spectrum

6-BROMO-1,2,4-TRIAZOLO[4,3-1]PYRIDINE(108281-79-4)¹HNMR

108281-79-4 (6-Bromo-1,2,4-triazolo[4,3-1]pyridine) Related Search:

5-(1H-Imidazol-1-yl)-2-pyridinamine 6-Bromo-[1,2,4]triazolo[1,5-a]pyridine 5-Bromo[1,2,4]triazolo[4,3-a]pyridine 6-Bromo-1,2,4-triazolo[4,3-1]pyridine 6-Bromo-3-tert-butyl-[1,2,4]triazolo[4,3-a]pyridine

6-Bromo-3-phenyl-[1,2,4]triazolo[4,3-a]pyridine 5-Bromo-1,2,3-triazolo[1,5-a]pyridine 6-Bromo-3-isopropyl-[1,2,4]triazolo[4,3-a]pyridine 5-Bromo-[1,2,4]triazolo[1,5-a]pyridine 8-Bromo-[1,2,4]triazolo[1,5-a]pyridine

8-bromo-[1,2,4]triazolo[4,3-a]pyridine-6-carboxylic acid 6-Bromo-3-(methylthio)-[1,2,4]triazolo[4,3-a]pyridine 6-Bromo-N-ethyl-[1,2,4]triazolo[4,3-a]pyridin-3-amine 6-Bromo-3-methyl-1,2,4-triazolo[4,3-a]-pyridine 6-Bromo-8-nitro-[1,2,4]triazolo[4,3-a]pyridine

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6-Bromo[1,2,4]triazolo[4,... 6-BROMO-TRIAZOLO[4,3-A]PYRIDINE 6-Bromo-[1,2,4]triazolo[4,3-a]pyridine 98% 1,2,4-Triazolo[4,3-a]pyridine, 6-bromo- 6-BROMO-1,2,4-TRIAZOLO[4,3-1]PYRIDINE ISO 9001：2015 REACH 6-Bromo-[1,2,4]triazolo[4,3-a]pyridine 6-BROMO-[1,2,4]TRIAZOLO[4,3-A]PYRIDINE 6-Bromo-1,2,4-triazolo[4,3-1]pyridine 108281-79-4 Heterocycle-Pyridine series blocks Pyridines