Quipazine
- CAS No.
- 4774-24-7
- Chemical Name:
- Quipazine
- Synonyms
- QUIPAZINE;TIMTEC-BB SBB011283;1-(2-quinolyl)piperazine;2-(1-Piperazino)quinoline;2-PIPERAZIN-1-YL-QUINOLINE;2-(1-piperazinyl)quinoline;2-(1-piperazinyl)-quinolin;1-(2-quinolinyl)piperazine;Quinoline, 2-(1-piperazinyl)-;Quipazine ISO 9001：2015 REACH
- CBNumber:
- CB2741602
- Molecular Formula:
- C13H15N3
- Molecular Weight:
- 213.28
- MDL Number:
- MFCD00242605
- MOL File:
- 4774-24-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 81-83 °C |
|---|---|
| Boiling point | 403.7±25.0 °C(Predicted) |
| Density | 1.152±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| form | Solid |
| pka | 8.93±0.10(Predicted) |
| color | Off-white to light yellow |
| CAS DataBase Reference | 4774-24-7(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 4WCY05C0SJ |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| RTECS | VC2513500 |
Quipazine price More Price(54)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 287937 | 2-Piperazin-1-yl-quinoline Asreported | 4774-24-7 | 500mg | $375 | 2026-06-03 | Buy |
| Usbiological | 287937 | 2-Piperazin-1-yl-quinoline Asreported | 4774-24-7 | 1g | $615 | 2026-06-03 | Buy |
| Usbiological | 287937 | 2-Piperazin-1-yl-quinoline Asreported | 4774-24-7 | 2g | $864 | 2026-06-03 | Buy |
| Usbiological | 287937 | 2-Piperazin-1-yl-quinoline Asreported | 4774-24-7 | 5g | $1218 | 2026-06-03 | Buy |
| AstaTech | 65558 | 2-PIPERAZIN-1-YL-QUINOLINE 97% | 4774-24-7 | 0.25G | $47 | 2026-04-30 | Buy |
Quipazine Chemical Properties, Uses, Production
Uses
antineoplastic
Definition
ChEBI: 2-(1-piperazinyl)quinoline is a member of pyridines and a member of piperazines.
Synthesis
110-85-0
612-62-4
4774-24-7
Step 1: Piperazine (10.20 g, 2.45 mmol) was dissolved in 15 mL of isopropanol in a dry round-bottomed flask under nitrogen protection. Subsequently, 2-chloroquinoline (0.20 g, 1.2 mmol) was added and the reaction mixture was heated and stirred at reflux for 24 hours. After completion of the reaction, water was added to the mixture and extracted with ethyl acetate. The organic layers were combined, washed with saturated sodium chloride solution, dried over anhydrous magnesium sulfate and concentrated under reduced pressure to remove the solvent. The crude product obtained was purified by silica gel column chromatography with eluent ratio of dichloromethane:methanol=4:1 to afford the target compound 2-(piperazin-1-yl)quinoline in 36% yield.
in vivo
Quipazine (2.5, 5 and 7.5 mg/kg, one dose for once; i.p.) affects dietary self-selection of different macronutrient diets in male and female rats[1].
References
[1] Patent: EP1724267, 2006, A1. Location in patent: Page/Page column 35; 68
[2] Journal of Medicinal Chemistry, 2010, vol. 53, # 21, p. 7549 - 7563
[3] Journal of Pharmaceutical Sciences, 1992, vol. 81, # 1, p. 99 - 103
[4] Chemical and Pharmaceutical Bulletin, 2001, vol. 49, # 10, p. 1314 - 1320
[5] Patent: WO2004/46124, 2004, A1. Location in patent: Page 41
Quipazine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Boyle Chemical Co., Ltd. | 021-50182298 021-50180596 | sales@boylechem.com | China | 2202 | 55 |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Beijing Yisiyan Technology Research Center | 010-56645598 13366904824; | bjkaida@163.com | China | 1596 | 59 |
| Shanghai Raise Chemical Technology Co.,Ltd | +86-021-50935922 | China | 7854 | 55 | |
| Shanghai TaoSu Biochemical Technology Co., Ltd. | 021-33632979 | info@tsbiochem.com | China | 8039 | 58 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Wuhan Chemduro Pharm Tech Co. Ltd. | 18040571231/1402788087 | China | 1972 | 58 | |
| ShangHai KenEn Chemical Technology Co., Ltd. | 13120367189;18621755571 | mychess007@163.com | China | 1994 | 55 |
| Shanghai ChuangYan Chemical Technology Co., Ltd. | 021-11111111 11111111111 | 546919421@qq.com | China | 3770 | 55 |
View Latest Price from Quipazine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | Quipazine
4774-24-7
|
$1.10 | 1g | 99.00% | 100 Tons | Dideu Industries Group Limited | |
 |
2026-08-08 | Quipazine
4774-24-7
|
$40.00 | 10g | TargetMol Chemicals Inc. | |||
 |
2025-04-04 | Quipazine
4774-24-7
|
1KG | 98% | 1ton | Henan Aochuang Chemical Co.,Ltd.
|
