4-Chlorophthalic anhydride
- CAS No.
- 118-45-6
- Chemical Name:
- 4-Chlorophthalic anhydride
- Synonyms
- 5-Chloroisobenzofuran-1,3-dione;CHLOROPHTHALIC ANHYDRIDE;4-Chlorophthalic;Chlorophtalicanhydre,95%;4-Chlorophtalic anhydride;4-Chlorophthalic anhydrid;oroisobenzofuran-1,3-dione;5-Chlorophthalic anhydride;ChlorophthalicAnhydride,4-;4-CHLOROPHTHALIC ANHYDRIDE
- CBNumber:
- CB2751645
- Molecular Formula:
- C8H3ClO3
- Molecular Weight:
- 182.56
- MDL Number:
- MFCD00152354
- MOL File:
- 118-45-6.mol
- TDS File:
- TDS
| Melting point | 96°C |
|---|---|
| Boiling point | 290 °C |
| Density | 1.594±0.06 g/cm3(Predicted) |
| vapor pressure | 0.058-0.058Pa at 25℃ |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | soluble in Toluene |
| form | Solid:particulate/powder |
| color | White to Almost white |
| InChI | InChI=1S/C8H3ClO3/c9-4-1-2-5-6(3-4)8(11)12-7(5)10/h1-3H |
| InChIKey | BTTRMCQEPDPCPA-UHFFFAOYSA-N |
| SMILES | C1(=O)C2=C(C=C(Cl)C=C2)C(=O)O1 |
| LogP | 2.713 |
| CAS DataBase Reference | 118-45-6(CAS DataBase Reference) |
| FDA UNII | BPI93D0O61 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H318 | |||||||||
| Precautionary statements | P280-P305+P351+P338-P310 | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36/37/39 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 2932990090 | |||||||||
| REACH Registrations | Inactive | |||||||||
| NFPA 704 |
|
4-Chlorophthalic anhydride price More Price(46)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | C1328 | 4-Chlorophthalic Anhydride >98.0%(GC)(T) | 118-45-6 | 5g | $111 | 2026-04-30 | Buy |
| TCI Chemical | C1328 | 4-Chlorophthalic Anhydride >98.0%(GC)(T) | 118-45-6 | 25g | $440 | 2026-04-30 | Buy |
| ChemScene | CS-W019466 | 5-Chloroisobenzofuran-1,3-dione ≥98% | 118-45-6 | 25g | $15 | 2026-06-04 | Buy |
| ChemScene | CS-W019466 | 5-Chloroisobenzofuran-1,3-dione ≥98% | 118-45-6 | 500g | $35 | 2026-06-04 | Buy |
| ChemScene | CS-W019466 | 5-Chloroisobenzofuran-1,3-dione ≥98% | 118-45-6 | 1kg | $66 | 2026-06-04 | Buy |
4-Chlorophthalic anhydride Chemical Properties, Uses, Production
Chemical Properties
4-Chlorophthalic anhydride has a melting point of around 99 °C. Like most acid anhydrides, it can hydrolyze in the presence of water.
Uses
4-chlorophthalic anhydride is an important monomer synthesis of polyimide and polyimide is considered to be the highest tolerance has been industrialized in the polymer and the shape and chemical stability of other materials can not like the outburst strength, wear resistance and extreme temperatures, excellent, has been widely used in aviation, aerospace, microelectronics and atom to the field of high technology. 4- of 4-chlorophthalic anhydride is mainly used in the synthesis of diphenyl ether dianhydride anhydride, two single and two double ether, thioether dianhydride anhydride two, two, and two amine polymerization ring was a series of polyimide engineering plastic with excellent performance. 4- of 4-chlorophthalic anhydride is not only the ideal raw material for the synthesis of various intermediates of polyimide, and can be used as a drug or pesticide.
Synthesis Reference(s)
Tetrahedron Letters, 23, p. 371, 1982 DOI: 10.1016/S0040-4039(00)86833-1
Preparation
A preparation method of 4-chlorophthalic anhydride uses monosodium phthalic acid as a raw material, uses water as a medium, uses a weak alkali solution as a pH regulator of a reaction system, and directly performs chlorination reaction with chlorine gas. The weak alkali solution is used as the pH regulator of the reaction system, which is beneficial to stabilizing the pH value of the reaction system, and can obtain high-yield 4-chlorophthalic acid monosodium coarse salt. The crude salt is desalted, dehydrated and closed to obtain a crude product of 4-chlorophthalic anhydride, which is purified by rectification to obtain high-purity 4-chlorophthalic anhydride.
4-Chlorophthalic anhydride Preparation Products And Raw materials
Raw materials
1of4
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanxi Libolong New Materials Co., Ltd | 19135980588 | 13935924147@163.cn | China | 17 | 58 |
| Chengdu Yuanda chemical co.,ltd | 028-85356300 18980937689 | chenquanxing@126.com | China | 161 | 55 |
| Liling Chuangli Technology Co. LTD | 0534-8101711 13606437406 | sales@chuanglichem.com | China | 49 | 58 |
| Shandong Dexin Fine Chemical Co., Ltd. | 18553366272 | 3091507995@qq.com | China | 278 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
View Latest Price from 4-Chlorophthalic anhydride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-17 | 4-Chlorophthalic anhydride
118-45-6
|
$800.00-990.00 | 1ton | 99% | 5000 | HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | |
 |
2026-09-17 | 4-Chlorophthalic anhydride
118-45-6
|
$48.84 | 25Kg/Drum | 99.00%HPLC | 5tons/month | Asia Chem I and E (Jiangsu) Co Ltd | |
 |
2026-09-02 | 4-Chlorophthalic anhydride
118-45-6
|
$1.20-35.00 | 1kg | 99% | Henan Fengda Chemical Co., Ltd |
-
- 4-Chlorophthalic anhydride
118-45-6
- $800.00-990.00
- 99%
- HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
-
- 4-Chlorophthalic anhydride
118-45-6
- $48.84
- 99.00%HPLC
- Asia Chem I and E (Jiangsu) Co Ltd
-
- 4-Chlorophthalic anhydride
118-45-6
- $1.20-35.00
- 99%
- Henan Fengda Chemical Co., Ltd
