Tetrachlorophthalic anhydride
- CAS No.
- 117-08-8
- Chemical Name:
- Tetrachlorophthalic anhydride
- Synonyms
- TCPA;4,5,6,7-Tetrachloroisobenzofuran-1,3-dione;tetrachlorophthalic;,5,6,7-Tetrachloro-isobenzofuran-1,3-dione;cp626;NIATHAL;TETRATHAL;orophthaL;Niagathal;NCI-C61585
- CBNumber:
- CB3313062
- Molecular Formula:
- C8Cl4O3
- Molecular Weight:
- 285.9
- MDL Number:
- MFCD00005920
- MOL File:
- 117-08-8.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Tetrachlorophthalic anhydride 96% | 131865 | 100g | $46.6 |
| Tetrachlorophthalic anhydride for synthesis | 8.00741 | 100g | $52.1 |
| Tetrachlorophthalic anhydride 96% | 131865 | 500g | $110.2 |
| Tetrachlorophthalic anhydride | T291510 | 250g | $215 |
| Tetrachlorophthalic anhydride 96% | 2H26-4-12 | 500g | $69 |
| More product size | |||
| Melting point | 253-257 °C(lit.) |
|---|---|
| Boiling point | 371 °C(lit.) |
| Density | 1.49 |
| vapor pressure | 0.16 mm Hg ( 145 °C) |
| Flash point | 362°C |
| storage temp. | Store below +30°C. |
| solubility | Chloroform (Slightly, Heated), DMSO (Heated), Methanol (Slightly, Heated) |
| pka | 3.01[at 20 ℃] |
| form | Flakes |
| color | White to off-white |
| Water Solubility | 0.8 mg/L (21 ºC) |
| Sensitive | Moisture Sensitive |
| BRN | 211560 |
| Exposure limits | ACGIH: TWA 0.002 mg/m3 (Skin) |
| Stability | Stable. Reacts with water. Combustible. Incompatible with strong oxidizing agents. Air and moisture sensitive. |
| InChI | 1S/C8Cl4O3/c9-3-1-2(8(14)15-7(1)13)4(10)6(12)5(3)11 |
| InChIKey | AUHHYELHRWCWEZ-UHFFFAOYSA-N |
| SMILES | Clc1c(Cl)c(Cl)c2C(=O)OC(=O)c2c1Cl |
| LogP | 3.2 at 25℃ |
| Indirect Additives used in Food Contact Substances | TETRACHLOROPHTHALIC ANHYDRIDE |
| CAS DataBase Reference | 117-08-8(CAS DataBase Reference) |
| EWG's Food Scores | 3 |
| FDA UNII | 76GLW0LBEK |
| NIST Chemistry Reference | 1,3-Isobenzofurandione, 4,5,6,7-tetrachloro-(117-08-8) |
| EPA Substance Registry System | Tetrachlorophthalic anhydride (117-08-8) |
| UNSPSC Code | 12352115 |
| NACRES | NA.23 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() ![]() ![]() GHS05,GHS08,GHS09 |
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|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H317-H318-H334-H350-H373-H410 | |||||||||
| Precautionary statements | P201-P261-P273-P280-P305+P351+P338-P308+P313 | |||||||||
| Hazard Codes | T,N,Xn | |||||||||
| Risk Statements | 45-41-42/43-50/53-48/22 | |||||||||
| Safety Statements | 53-22-24-26-37/39-45-60-61-36/37/39 | |||||||||
| RIDADR | UN 3077 9/PG 3 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | TI3450000 | |||||||||
| F | 10-21 | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 9 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29173990 | |||||||||
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
|||||||||
| Hazard Classifications | Aquatic Acute 1 Aquatic Chronic 1 Carc. 1B Eye Dam. 1 Resp. Sens. 1 Skin Sens. 1 STOT RE 2 |
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| Hazardous Substances Data | 117-08-8(Hazardous Substances Data) | |||||||||
| Toxicity | LD50 orally in Rabbit: > 15800 mg/kg LD50 dermal Rabbit > 5000 mg/kg | |||||||||
| NFPA 704 |
|
Tetrachlorophthalic anhydride price More Price(16)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 131865 | Tetrachlorophthalic anhydride 96% | 117-08-8 | 100g | $46.6 | 2025-07-31 | Buy |
| Sigma-Aldrich | 8.00741 | Tetrachlorophthalic anhydride for synthesis | 117-08-8 | 100g | $52.1 | 2025-07-31 | Buy |
| Sigma-Aldrich | 131865 | Tetrachlorophthalic anhydride 96% | 117-08-8 | 500g | $110.2 | 2025-07-31 | Buy |
| TRC | T291510 | Tetrachlorophthalic anhydride | 117-08-8 | 250g | $215 | 2021-12-16 | Buy |
| SynQuest Laboratories | 2H26-4-12 | Tetrachlorophthalic anhydride 96% | 117-08-8 | 500g | $69 | 2021-12-16 | Buy |
Tetrachlorophthalic anhydride Chemical Properties,Uses,Production
Chemical Properties
white needle-like crystals or powder
Uses
Intermediate in dyes, pharmaceuticals, plasticizers, and other organic materials; flame-retardant in epoxy resins.
Uses
Tetrachlorophthalic Anhydride is used in the synthesis of nucleoside analogues with a specific structure as apoptosis inducing active compounds. Also used in the synthesis of carbonic anhydrase inhbitors. Chlorinated Reactive Flame Retardant Intermediate
Definition
ChEBI: A cyclic dicarboxylic anhydride that is phthalic anhydride chlorinated at the 4-, 5-, 6- and 7-positions.
General Description
Odorless needle-like crystals or white powder.
Air & Water Reactions
Sensitive to air and moisture.
Reactivity Profile
4,5,6,7-Tetrachloro-1,3-isobenzofurandione reacts exothermically with water. This reaction is expected to be slow, but can become vigorous if local heating accelerates it. Reaction with water is accelerated by acids. Incompatible with acids, strong oxidizing agents, alcohols, amines, and bases.
Fire Hazard
Flash point data for 4,5,6,7-Tetrachloro-1,3-isobenzofurandione are not available. 4,5,6,7-Tetrachloro-1,3-isobenzofurandione is probably combustible.
Flammability and Explosibility
Not classified
Purification Methods
Crystallise the anhydride from chloroform or *benzene, then sublime it in a vacuum. [Beilstein 17/11 V 260.]
Tetrachlorophthalic anhydride Preparation Products And Raw materials
Raw materials
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Preparation Products
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| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Yanxi Chemical Co., Ltd. | +8618531123677 | faithe@yan-xi.com | China | 5853 | 58 |
| Capot Chemical Co.,Ltd. | +86-(0)57185586718; +8613336195806 | sales@capot.com | China | 29735 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21595 | 55 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +8618949832763 | info@tnjchem.com | China | 2988 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29830 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| Richest Group Ltd | 18017061086 | oled@richest-group.com | CHINA | 5600 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30228 | 58 |
View Lastest Price from Tetrachlorophthalic anhydride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-06-20 | Tetrachlorophthalic anhydride
117-08-8
|
US $30.00-10.00 / kg | 1kg | 0.99 | 10 tons | Hebei Yanxi Chemical Co., Ltd. | |
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2020-06-02 | Tetrachlorophthalic anhydride 117-08-8
117-08-8
|
US $12.50 / KG | 1KG | 99.0% in stock | 1500 MT per month | Chemwill Asia Co.,Ltd. | |
![]() |
2020-06-02 | 4,5,6,7-Tetrachloro-1,3-isobenzofurandione 117-08-8
117-08-8
|
US $15.50 / KG | 1KG | 99.0% in stock | 1600 MT per month | Chemwill Asia Co.,Ltd. |
-

- Tetrachlorophthalic anhydride
117-08-8
- US $30.00-10.00 / kg
- 0.99
- Hebei Yanxi Chemical Co., Ltd.
-

- Tetrachlorophthalic anhydride 117-08-8
117-08-8
- US $12.50 / KG
- 99.0% in stock
- Chemwill Asia Co.,Ltd.
-

- 4,5,6,7-Tetrachloro-1,3-isobenzofurandione 117-08-8
117-08-8
- US $15.50 / KG
- 99.0% in stock
- Chemwill Asia Co.,Ltd.
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