SB 243213 dihydrochloride
- CAS No.
- 1780372-25-9
- Chemical Name:
- SB 243213 dihydrochloride
- Synonyms
- 5-Methyl-N-{6-[(2-methylpyridin-3-yl)oxy]pyridin-3-yl}-6-(trifluoromethyl)-2,3-dihydro-1H-indole-1-carboxamide dihydrochloride
- CBNumber:
- CB28054537
- Molecular Formula:
- C22H20ClF3N4O2
- Molecular Weight:
- 464.87
- MDL Number:
- MFCD22683796
- MOL File:
- 1780372-25-9.mol
SB 243213 dihydrochloride Chemical Properties,Uses,Production
Uses
SB 243213 Dihydrochloride is a 5-HT2c receptor antagonist.
in vivo
SB 243213 dihydrochloride (0.1-10 mg/kg; p.o.; 1 h pre-test) dose-dependently and significantly increases the amount of time rats spent in social interaction over 15 min under brightly lit conditions and in an unfamiliar test box[1].
SB 243213 dihydrochloride (0.3 mg/kg; p.o.; 1 h pre-test) significantly increases time spent in social interaction[1].
Animal Model: | Male Sprague-Dawley experimentally naive rats (220-300 g)[1] |
Dosage: | 0.1, 0.3, 1, 3, 10 mg/kg |
Administration: | p.o.; 1 hour pre-test |
Result: | Dose-dependently and significantly increased the amount of time rats spent in social interaction over 15 min under brightly lit conditions and in an unfamiliar test box. |
IC 50
Human 5-HT2C Receptor: 9.37 (pKi); human 5-HT1A Receptor: <5.3 (pKi); human 5-HT1B Receptor: 5.5 (pKi); human 5-HT1D Receptor: 6.32 (pKi); human 5-HT1E Receptor: <5.4 (pKi); human 5-HT1F Receptor: 5.35 (pKi); Human 5-HT2A Receptor: 7.01 (pKi); human 5-HT2B Receptor: 7.2 (pKi); Human 5-HT6 Receptor: 6.5 (pKi); Human 5-HT7 Receptor: 5.64 (pKi)
SB 243213 dihydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
SB 243213 dihydrochloride Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32432 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39031 | 58 |
Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
cjbscvictory | 13348960310 | 3003867561@qq.com | China | 10505 | 58 |
Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223; | psaitong@jm-bio.com | China | 29770 | 58 |
Beijing Biocreative Technology Co., Ltd. | 15522676233 | 3007606172@qq.com | China | 1248 | 58 |
TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24989 | 58 |
Nantong QuanYi Biotechnology Co., Ltd | 0513-66337626 18051384581 | sales@chemhifuture.com | China | 5840 | 58 |
Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11973 | 58 |
Cayman Chemical Company | 800-364-9897 | sales@caymanchem.com | China | 6838 | 58 |
View Lastest Price from SB 243213 dihydrochloride manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2025-08-21 | SB 243213 dihydrochloride
1780372-25-9
|
US $478.00-159.00 / mg | 10g | TargetMol Chemicals Inc. |
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- SB 243213 dihydrochloride
1780372-25-9
- US $478.00-159.00 / mg
- TargetMol Chemicals Inc.