SB 200646 hydrochloride
- CAS No.
- 143797-62-0
- Chemical Name:
- SB 200646 hydrochloride
- Synonyms
- SB-200646A;SB-200646A ，S0893;SB 200646A,SB200646A;SB 200646 hydrochloride, 5-HT2C/2B receptor antagonist;1-(1-Methyl-1H-indol-5-yl)-3-(pyridin-3-yl)urea hydrochloride
- CBNumber:
- CB6497473
- Molecular Formula:
- C15H14N4O.ClH
- Molecular Weight:
- 302.763
- MDL Number:
- MFCD00913519
- MOL File:
- 143797-62-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H335-H315-H319 |
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
SB 200646 hydrochloride price More Price(36)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 30973 | SB-200646 (hydrochloride) ≥98% | 143797-62-0 | 1mg | $36 | 2026-04-30 | Buy |
| Cayman Chemical | 30973 | SB-200646 (hydrochloride) ≥98% | 143797-62-0 | 5mg | $128 | 2026-04-30 | Buy |
| Cayman Chemical | 30973 | SB-200646 (hydrochloride) ≥98% | 143797-62-0 | 10mg | $236 | 2026-04-30 | Buy |
| Biosynth | TFA79762 | SB-200646A | 143797-62-0 | 25mg | $1034.5 | 2026-06-05 | Buy |
| Biosynth | TFA79762 | SB-200646A | 143797-62-0 | 50mg | $1439.5 | 2026-06-05 | Buy |
SB 200646 hydrochloride Chemical Properties, Uses, Production
Uses
SB 200646 Hydrochloride is a 5-HT2C antagonist.
in vivo
SB-200646A (20 mg/kg; intravenous injection; daily; for 21 days; male albino Sprague-Dawley rats) treatment significantly decreases the number of spontaneously active ventral tegmental area (VTA) dopaminergic neurons[1].
The i.v. administration of 4-16 mg/kg of SB-200646A significantly increases the firing rate and % events as bursts in spontaneously active VTA dopaminergic neurons and significantly increases the % events as burst in substantia nigra pars compacta (SNC) dopaminergic neurons[1].
| Animal Model: | Male albino Sprague-Dawley rats (200-225 g at the beginning of treatment and 300-350 g at the time of the experiment)[1] |
| Dosage: | 20 mg/kg |
| Administration: | Intravenous injection; daily; for 21 days |
| Result: | Significantly decreased the number of spontaneously active ventral tegmental area (VTA) dopaminergic neurons. |
IC 50
5-HT2B Receptor: 7.5 (pKi); 5-HT2C Receptor: 6.9 (pKi); 5-HT2A Receptor: 5.2 (pKi)
SB 200646 hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
SB 200646 hydrochloride Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 9780 | 55 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| Jinan Jiuli Biotechnology Co. , Ltd. | 15865264761 | 486064515@qq.com | China | 5000 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 | psaitong@jm-bio.com | China | 27626 | 58 |
| Bide Pharmatech Ltd. | 400-1647117 13681763483 | product02@bidepharm.com | China | 59929 | 58 |
| Kaifeng Mingren Pharmaceutical Co.,LTD | 0371-65741762 | sales@hasunny.com | China | 2377 | 58 |
| PureChemland Co.,Ltd. | 13540909846 13882008651 | 3848291069@qq.com | China | 3000 | 58 |
View Latest Price from SB 200646 hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-15 | SB-200646A
143797-62-0
|
$35.00 | 10g | TargetMol Chemicals Inc. |
-
- SB-200646A
143797-62-0
- $35.00
- TargetMol Chemicals Inc.
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