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Acetamide, N-cyclohexyl-2-[(4,5-dihydro-5-methyl-4-oxo-3-phenyl-3H-pyrimido[5,4-b]indol-2-yl)thio]-

Acetamide, N-cyclohexyl-2-[(4,5-dihydro-5-methyl-4-oxo-3-phenyl-3H-pyrimido[5,4-b]indol-2-yl)thio]- structure

CAS No.: 1438280-73-9

Chemical Name:: Acetamide, N-cyclohexyl-2-[(4,5-dihydro-5-methyl-4-oxo-3-phenyl-3H-pyrimido[5,4-b]indol-2-yl)thio]-

Synonyms: 1Z105;Acetamide, N-cyclohexyl-2-[(4,5-dihydro-5-methyl-4-oxo-3-phenyl-3H-pyrimido[5,4-b]indol-2-yl)thio]-

CBNumber:: CB28237040

Molecular Formula:: C25H26N4O2S

Molecular Weight:: 446.56

MDL Number:

MOL File:: 1438280-73-9.mol

MSDS File:: SDS

Last updated:2025-04-18 09:51:55

Request For Quotation

Acetamide, N-cyclohexyl-2-[(4,5-dihydro-5-methyl-4-oxo-3-phenyl-3H-pyrimido[5,4-b]indol-2-yl)thio]- Properties

Density	1.34±0.1 g/cm3(Predicted)
pka	14.14±0.20(Predicted)
FDA UNII	YS8VEM6ZWU

Acetamide, N-cyclohexyl-2-[(4,5-dihydro-5-methyl-4-oxo-3-phenyl-3H-pyrimido[5,4-b]indol-2-yl)thio]- Chemical Properties, Uses, Production

Uses

1Z105 is an oral active TLR4/MD2 ligand. 1Z105 enhances dendritic cell maturation and antigen presentation and prevents rthritis[1][2].

References

[1] Goff PH, et al. Synthetic Toll-like receptor 4 (TLR4) and TLR7 ligands as influenza virus vaccine adjuvants induce rapid, sustained, and broadly protective responses. J Virol. 2015;89(6):3221-3235. DOI:10.1128/JVI.03337-14
[2] Hayashi T, et al. Novel synthetic toll-like receptor 4/MD2 ligands attenuate sterile inflammation. J Pharmacol Exp Ther. 2014;350(2):330-340. DOI:10.1124/jpet.114.214312

Acetamide, N-cyclohexyl-2-[(4,5-dihydro-5-methyl-4-oxo-3-phenyl-3H-pyrimido[5,4-b]indol-2-yl)thio]- Preparation Products And Raw materials

Raw materials

Preparation Products

Acetamide, N-cyclohexyl-2-[(4,5-dihydro-5-methyl-4-oxo-3-phenyl-3H-pyrimido[5,4-b]indol-2-yl)thio]- Suppliers

Global Suppliers ( 1)

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29874	58

Supplier	Advantage
TargetMol Chemicals Inc.	58

1438280-73-9 (Acetamide, N-cyclohexyl-2-[(4,5-dihydro-5-methyl-4-oxo-3-phenyl-3H-pyrimido[5,4-b]indol-2-yl)thio]-) Related Search:

Lipopolysaccharides, from E. coli O55:B5 TLR4 Protein, Human (sf9, His, Solution) TLR2 protein, mouse (SF9, his) TLR3 Protein, CYNOMOLGUS (681A.A, HEK293, HIS) TLR3 Protein, Human (HEK293, Fc)

TLR2 protein, RAT (SF9, HIS)

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Acetamide, N-cyclohexyl-2-[(4,5-dihydro-5-methyl-4-oxo-3-phenyl-3H-pyrimido[5,4-b]indol-2-yl)thio]- 1Z105 1438280-73-9