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5-Bromo-2-chloro-pyridin-3-ol

5-Bromo-2-chloro-pyridin-3-ol structure

CAS No.: 286946-77-8

Chemical Name:: 5-Bromo-2-chloro-pyridin-3-ol

Synonyms: 5-Bromo-2-chloro-3-hydroxypyridine;CML-034;5-bromo-2-chloropyridin-3-o;5-Bromo-2-chloro-3-pyridinol;5-Bromo-2-chloropyridine-3-ol;5-Bromo-2-chloro-pyridin-3-ol;3-Pyridinol, 5-bromo-2-chloro-;5-Bromo-2-chloro-2-hydroxypyridine;2-Chloro-3-hydroxy-5-broMopyridine;5-BROMO-2-CHLORO-PYRIDIN-3-OL ISO 9001：2015 REACH

CBNumber:: CB2836623

Molecular Formula:: C5H3BrClNO

Molecular Weight:: 208.44

MDL Number:: MFCD08688592

MOL File:: 286946-77-8.mol

MSDS File:: SDS

Last updated:2026-09-12 18:51:27

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5-Bromo-2-chloro-pyridin-3-ol Properties

Melting point	182-183 °C
Boiling point	338.1±37.0 °C(Predicted)
Density	1.908±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
pka	3.54±0.10(Predicted)
Appearance	White to off-white Solid
InChIKey	KVDIPLHFSIUSIK-UHFFFAOYSA-N

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS06
Signal word	Danger
Hazard statements	H301
Precautionary statements	P301+P310
Hazard Codes	Xi,T
Risk Statements	25
Safety Statements	45
WGK Germany	3
HazardClass	IRRITANT
HS Code	2933399990

5-Bromo-2-chloro-pyridin-3-ol price More Price(64)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	ADE000395	5-Bromo-2-chloro-pyridin-3-ol Aldrich	286946-77-8	1g	$463	2023-01-07	Buy
AstaTech	52834	5-BROMO-2-CHLORO-3-HYDROXY-PYRIDINE 95%	286946-77-8	1G	$34	2026-04-30	Buy
AstaTech	52834	5-BROMO-2-CHLORO-3-HYDROXY-PYRIDINE 95%	286946-77-8	5G	$89	2026-04-30	Buy
AstaTech	52834	5-BROMO-2-CHLORO-3-HYDROXY-PYRIDINE 95%	286946-77-8	100G	$277	2026-04-30	Buy
Apolloscientific	OR315101	5-Bromo-2-chloropyridin-3-ol >98%	286946-77-8	1g	$22	2026-06-04	Buy

Product number	Packaging	Price	Buy
ADE000395	1g	$463	Buy
52834	1G	$34	Buy
52834	5G	$89	Buy
52834	100G	$277	Buy
OR315101	1g	$22	Buy

5-Bromo-2-chloro-pyridin-3-ol Chemical Properties, Uses, Production

Chemical Properties

Yellow solid

Synthesis

286947-03-3

286946-77-8

5-Bromo-2-chloro-3-methoxypyridine (36 g, 162 mmol) was used as the raw material, which was dissolved in hydrobromic acid (200 mL, 3683 mmol) and the reaction was stirred at 100 °C for 48 hours. Upon completion of the reaction, the reaction mixture was concentrated and the pH was adjusted to alkaline with saturated NaHCO3 solution, followed by extraction with EtOAc (600 mL x 2). The organic phases were combined, washed with brine, dried over anhydrous Na2SO4, filtered and concentrated. The crude product was purified by silica gel column chromatography (eluent: petroleum ether/EtOAc, 10:1). All fractions that were shown to contain the target product by TLC (unfolding agent: petroleum ether/EtOAc, 2:1, Rf=0.6) were collected, combined and concentrated to give 5-bromo-2-chloropyridin-3-ol (21 g, 86 mmol, 52.9% yield) as a light yellow oil.1H NMR (400 MHz, methanol-d4) δ 7.96 (t, J=2.0 Hz, 1H), 7.47 (d, J=2.4 Hz, 1H).ESI-LCMS m/z 208.0, 210.0 ([M+H]+).

References

[1] Patent: WO2016/37578, 2016, A1. Location in patent: Page/Page column 103

5-Bromo-2-chloro-pyridin-3-ol Preparation Products And Raw materials

Raw materials

3-Bromo-5-hydroxypyridine 2-Chloro-3-Bromo-5-Hydroxypyridine 5-Bromo-2-chloro-3-methoxypyridine 3-(Benzyloxy)-5-broMo-2-chloropyridine Sodium hypochlorite

Preparation Products

5-Bromo-2-chloro-pyridin-3-ol Suppliers

Global Suppliers ( 148)

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai shallow overflow new Materials Co. , Ltd.	86-18372897-544 18995560451	1308815138@qq.com	China	496	58
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Changzhou Huanling Chemical Co., Ltd.	89803005 18206112582	info@huanlingchem.com	China	983	68
Jia Xing Isenchem Co.,Ltd	0573-85285100 18627885956	isenchem@163.com	China	9389	66
Accela ChemBio Co.,Ltd.	021-50795510 4000665055	marketing@accelachem.com	China	10972	64
Shanghai Longsheng chemical Co.,Ltd.	58099637 13585536065	sales@shlschem.com	China	9880	59
Nanjing Chemlin Chemical Co., Ltd	025-83697070 13770331960	info@chemlin.com.cn	China	16306	64
Shanghai Hanhong Scientific Co.,Ltd.	021-54306202 13764082696	info@hanhongsci.com	China	42917	64
Nan Jing Dirise Chemcial Co.,LTD	025-52161033 15312098939	2432674894@qq.com	China	585	64
Beijing HengPuGao Pharmaceutical Chemistry Technology Co., Ltd.	010-81520996 13439320863	hengpugao@126.com	China	159	57

Supplier	Advantage
Shanghai shallow overflow new Materials Co. , Ltd.	58
J & K SCIENTIFIC LTD.	76
Changzhou Huanling Chemical Co., Ltd.	68
Jia Xing Isenchem Co.,Ltd	66
Accela ChemBio Co.,Ltd.	64
Shanghai Longsheng chemical Co.,Ltd.	59
Nanjing Chemlin Chemical Co., Ltd	64
Shanghai Hanhong Scientific Co.,Ltd.	64
Nan Jing Dirise Chemcial Co.,LTD	64
Beijing HengPuGao Pharmaceutical Chemistry Technology Co., Ltd.	57

View Latest Price from 5-Bromo-2-chloro-pyridin-3-ol manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-08-20	5-BROMO-2-CHLORO-PYRIDIN-3-OL 286946-77-8	$1.10	1g	99.00%	100 Tons min	Dideu Industries Group Limited
	2020-03-08	5-BROMO-2-CHLORO-PYRIDIN-3-OL 286946-77-8	$2.00	1KG	99%min	500kg	Career Henan Chemical Co

5-BROMO-2-CHLORO-PYRIDIN-3-OL
286946-77-8
$1.10
99.00%
Dideu Industries Group Limited

5-BROMO-2-CHLORO-PYRIDIN-3-OL
286946-77-8
$2.00
99%min
Career Henan Chemical Co

5-Bromo-2-chloro-pyridin-3-ol Spectrum

5-BROMO-2-CHLORO-PYRIDIN-3-OL(286946-77-8)¹HNMR

286946-77-8 (5-Bromo-2-chloro-pyridin-3-ol) Related Search:

3,5,6-Trichloropyrid 2-Chloro-3-hydroxypyridine 3-Bromo-5-hydroxypyridine 5-Bromo-2-chloro-pyridin-3-ol 5-Bromo-2-chloro-3-methoxypyridine

2-Chloro-3-Bromo-5-Hydroxypyridine

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2-Chloro-3-hydroxy-5-broMopyridine 5-Bromo-2-chloro-2-hydroxypyridine 5-bromo-2-chloropyridin-3-o CML-034 3-Pyridinol, 5-bromo-2-chloro- 5-BROMO-2-CHLORO-PYRIDIN-3-OL ISO 9001：2015 REACH 5-Bromo-2-chloro-3-pyridinol 5-Bromo-2-chloropyridine-3-ol 5-Bromo-2-chloro-3-hydroxypyridine 5-Bromo-2-chloro-pyridin-3-ol 286946-77-8