5-BROMO-2-CHLORO-PYRIDIN-3-OL
- CAS No.
- 286946-77-8
- Chemical Name:
- 5-BROMO-2-CHLORO-PYRIDIN-3-OL
- Synonyms
- CML-034;5-bromo-2-chloropyridin-3-o;5-Bromo-2-chloro-3-pyridinol;5-Bromo-2-chloropyridine-3-ol;5-BROMO-2-CHLORO-PYRIDIN-3-OL;3-Pyridinol, 5-bromo-2-chloro-;5-Bromo-2-chloro-3-hydroxypyridine;5-Bromo-2-chloro-2-hydroxypyridine;2-Chloro-3-hydroxy-5-broMopyridine;5-BROMO-2-CHLORO-PYRIDIN-3-OL ISO 9001:2015 REACH
- CBNumber:
- CB2836623
- Molecular Formula:
- C5H3BrClNO
- Molecular Weight:
- 208.44
- MDL Number:
- MFCD08688592
- MOL File:
- 286946-77-8.mol
- MSDS File:
- SDS
5-BROMO-2-CHLORO-PYRIDIN-3-OL price More Price(35)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | ADE000395 | 5-Bromo-2-chloro-pyridin-3-ol Aldrich | 286946-77-8 | 1g | $463 | 2023-01-07 | Buy |
TRC | B682788 | 5-Bromo-2-chloro-pyridin-3-ol | 286946-77-8 | 250mg | $75 | 2021-12-16 | Buy |
Biosynth Carbosynth | FB139926 | 5-Bromo-2-chloropyridin-3-ol | 286946-77-8 | 500mg | $90 | 2021-12-16 | Buy |
Biosynth Carbosynth | FB139926 | 5-Bromo-2-chloropyridin-3-ol | 286946-77-8 | 1g | $140 | 2021-12-16 | Buy |
ChemScene | CS-W003542 | 5-Bromo-2-chloropyridin-3-ol >97.0% | 286946-77-8 | 5g | $170 | 2021-12-16 | Buy |
5-BROMO-2-CHLORO-PYRIDIN-3-OL Chemical Properties,Uses,Production
Chemical Properties
Yellow solid
Synthesis

286947-03-3

286946-77-8
5-Bromo-2-chloro-3-methoxypyridine (36 g, 162 mmol) was used as the raw material, which was dissolved in hydrobromic acid (200 mL, 3683 mmol) and the reaction was stirred at 100 °C for 48 hours. Upon completion of the reaction, the reaction mixture was concentrated and the pH was adjusted to alkaline with saturated NaHCO3 solution, followed by extraction with EtOAc (600 mL x 2). The organic phases were combined, washed with brine, dried over anhydrous Na2SO4, filtered and concentrated. The crude product was purified by silica gel column chromatography (eluent: petroleum ether/EtOAc, 10:1). All fractions that were shown to contain the target product by TLC (unfolding agent: petroleum ether/EtOAc, 2:1, Rf=0.6) were collected, combined and concentrated to give 5-bromo-2-chloropyridin-3-ol (21 g, 86 mmol, 52.9% yield) as a light yellow oil.1H NMR (400 MHz, methanol-d4) δ 7.96 (t, J=2.0 Hz, 1H), 7.47 (d, J=2.4 Hz, 1H).ESI-LCMS m/z 208.0, 210.0 ([M+H]+).
References
[1] Patent: WO2016/37578, 2016, A1. Location in patent: Page/Page column 103
5-BROMO-2-CHLORO-PYRIDIN-3-OL Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49730 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29804 | 58 |
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 21669 | 58 |
View Lastest Price from 5-BROMO-2-CHLORO-PYRIDIN-3-OL manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2021-09-04 | 5-BROMO-2-CHLORO-PYRIDIN-3-OL
286946-77-8
|
US $1.10 / g | 1g | 99.00% | 100 Tons min | Dideu Industries Group Limited | |
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2020-03-08 | 5-BROMO-2-CHLORO-PYRIDIN-3-OL
286946-77-8
|
US $2.00 / KG | 1KG | 99%min | 500kg | Career Henan Chemical Co |
-
- 5-BROMO-2-CHLORO-PYRIDIN-3-OL
286946-77-8
- US $1.10 / g
- 99.00%
- Dideu Industries Group Limited
-
- 5-BROMO-2-CHLORO-PYRIDIN-3-OL
286946-77-8
- US $2.00 / KG
- 99%min
- Career Henan Chemical Co