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5-BROMO-2-CHLORO-PYRIDIN-3-OL

CAS No.
286946-77-8
Chemical Name:
5-BROMO-2-CHLORO-PYRIDIN-3-OL
Synonyms
CML-034;5-bromo-2-chloropyridin-3-o;5-Bromo-2-chloro-3-pyridinol;5-Bromo-2-chloropyridine-3-ol;5-BROMO-2-CHLORO-PYRIDIN-3-OL;3-Pyridinol, 5-bromo-2-chloro-;5-Bromo-2-chloro-3-hydroxypyridine;5-Bromo-2-chloro-2-hydroxypyridine;2-Chloro-3-hydroxy-5-broMopyridine;5-BROMO-2-CHLORO-PYRIDIN-3-OL ISO 9001:2015 REACH
CBNumber:
CB2836623
Molecular Formula:
C5H3BrClNO
Molecular Weight:
208.44
MDL Number:
MFCD08688592
MOL File:
286946-77-8.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:48

5-BROMO-2-CHLORO-PYRIDIN-3-OL Properties

Melting point 182-183 °C
Boiling point 338.1±37.0 °C(Predicted)
Density 1.908±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka 3.54±0.10(Predicted)
Appearance White to off-white Solid
InChIKey KVDIPLHFSIUSIK-UHFFFAOYSA-N

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS06
Signal word  Danger
Hazard statements  H301
Precautionary statements  P301+P310
Hazard Codes  Xi,T
Risk Statements  25
Safety Statements  45
WGK Germany  3
HazardClass  IRRITANT
HS Code  2933399990

5-BROMO-2-CHLORO-PYRIDIN-3-OL price More Price(35)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich ADE000395 5-Bromo-2-chloro-pyridin-3-ol Aldrich 286946-77-8 1g $463 2023-01-07 Buy
TRC B682788 5-Bromo-2-chloro-pyridin-3-ol 286946-77-8 250mg $75 2021-12-16 Buy
Biosynth Carbosynth FB139926 5-Bromo-2-chloropyridin-3-ol 286946-77-8 500mg $90 2021-12-16 Buy
Biosynth Carbosynth FB139926 5-Bromo-2-chloropyridin-3-ol 286946-77-8 1g $140 2021-12-16 Buy
ChemScene CS-W003542 5-Bromo-2-chloropyridin-3-ol >97.0% 286946-77-8 5g $170 2021-12-16 Buy
Product number Packaging Price Buy
ADE000395 1g $463 Buy
B682788 250mg $75 Buy
FB139926 500mg $90 Buy
FB139926 1g $140 Buy
CS-W003542 5g $170 Buy

5-BROMO-2-CHLORO-PYRIDIN-3-OL Chemical Properties,Uses,Production

Chemical Properties

Yellow solid

Synthesis

5-BROMO-2-CHLORO-3-METHOXYPYRIDINE

286947-03-3

5-BROMO-2-CHLORO-PYRIDIN-3-OL

286946-77-8

5-Bromo-2-chloro-3-methoxypyridine (36 g, 162 mmol) was used as the raw material, which was dissolved in hydrobromic acid (200 mL, 3683 mmol) and the reaction was stirred at 100 °C for 48 hours. Upon completion of the reaction, the reaction mixture was concentrated and the pH was adjusted to alkaline with saturated NaHCO3 solution, followed by extraction with EtOAc (600 mL x 2). The organic phases were combined, washed with brine, dried over anhydrous Na2SO4, filtered and concentrated. The crude product was purified by silica gel column chromatography (eluent: petroleum ether/EtOAc, 10:1). All fractions that were shown to contain the target product by TLC (unfolding agent: petroleum ether/EtOAc, 2:1, Rf=0.6) were collected, combined and concentrated to give 5-bromo-2-chloropyridin-3-ol (21 g, 86 mmol, 52.9% yield) as a light yellow oil.1H NMR (400 MHz, methanol-d4) δ 7.96 (t, J=2.0 Hz, 1H), 7.47 (d, J=2.4 Hz, 1H).ESI-LCMS m/z 208.0, 210.0 ([M+H]+).

References

[1] Patent: WO2016/37578, 2016, A1. Location in patent: Page/Page column 103

5-BROMO-2-CHLORO-PYRIDIN-3-OL Preparation Products And Raw materials

Global( 145)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 33024 60
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28172 58
Accela ChemBio Inc.
+1-858-6993322 info@accelachem.com United States 21193 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49730 58
career henan chemical co
+86-0371-86658258 +8613203830695 factory@coreychem.com China 29804 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd
+8613580539051 joe@yuhengpharm.com CHINA 21142 58
SIMAGCHEM CORP
+86-5922680277 +86-13806087780 sale@simagchem.com China 17346 58
ANHUI WITOP BIOTECH CO., LTD
+8615255079626 eric@witopchemical.com China 23541 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250 1026@dideu.com China 21669 58

View Lastest Price from 5-BROMO-2-CHLORO-PYRIDIN-3-OL manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
5-BROMO-2-CHLORO-PYRIDIN-3-OL pictures 2021-09-04 5-BROMO-2-CHLORO-PYRIDIN-3-OL
286946-77-8
US $1.10 / g 1g 99.00% 100 Tons min Dideu Industries Group Limited
5-BROMO-2-CHLORO-PYRIDIN-3-OL pictures 2020-03-08 5-BROMO-2-CHLORO-PYRIDIN-3-OL
286946-77-8
US $2.00 / KG 1KG 99%min 500kg Career Henan Chemical Co

5-BROMO-2-CHLORO-PYRIDIN-3-OL Spectrum

2-Chloro-3-hydroxy-5-broMopyridine 5-Bromo-2-chloro-2-hydroxypyridine 5-bromo-2-chloropyridin-3-o 5-BROMO-2-CHLORO-PYRIDIN-3-OL 5-Bromo-2-chloro-3-hydroxypyridine CML-034 3-Pyridinol, 5-bromo-2-chloro- 5-BROMO-2-CHLORO-PYRIDIN-3-OL ISO 9001:2015 REACH 5-Bromo-2-chloro-3-pyridinol 5-Bromo-2-chloropyridine-3-ol 286946-77-8