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IL-17A inhibitor 1

IL-17A inhibitor 1 structure

CAS No.: 2452464-73-0

Chemical Name:: IL-17A inhibitor 1

Synonyms: LY3509754;LY-3533028;IL-17A inhibitor 1;IL-17A inhibitor 1, 10 mM in DMSO;inhibit,Inhibitor,Interleukin Related,COPD,Asthma,IL-17A inhibitor 1,IL17A inhibitor 1,IL 17A inhibitor 1;1,2,5-Oxadiazole-3-carboxamide, N-[(S)-(4,4-difluorocyclohexyl)[7-[(1S)-2-methoxy-1-[(4S)-2-oxo-4-(trifluoromethyl)-1-imidazolidinyl]ethyl]imidazo[1,2-b]pyridazin-2-yl]methyl]-4-methyl-

CBNumber:: CB28529477

Molecular Formula:: C24H27F5N8O4

Molecular Weight:: 586.51

MDL Number:: MFCD34474218

MOL File:: 2452464-73-0.mol

Last updated:2026-01-15 14:49:44

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IL-17A inhibitor 1 Properties

Density	1+-.0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
form	Solid
pka	11.52±0.46(Predicted)
color	Off-white to yellow
InChIKey	MVWVCLAORBNXSD-UWVAXJGDSA-N
SMILES	O1N=C(C)C(C(N[C@@H](C2CCC(F)(F)CC2)C2=CN3C(=N2)C=C([C@H](N2C(=O)N[C@H](C(F)(F)F)C2)COC)C=N3)=O)=N1

IL-17A inhibitor 1 Chemical Properties,Uses,Production

Uses

LY3509754 (IL-17A inhibitor 1) is a IL-17A inhibitor, with IC50 values of <9.45 nM and 9.3 nM in alphalisa assay and HT-29 cells[1].

Biological Activity

IL-17A inhibitor 1 (example 24) is a IL-17A inhibitor, with IC50 values of <9.45 nM and 9.3 nM in alphalisa assay and HT-29 cells[1]. IL-17A inhibitor 1 (example 24) possesses high oral bioavailability (F=107%)[1].

in vivo

LY3509754 (example 24) possesses high oral bioavailability (F=107%)^[1].

IC 50

IL-17

References

[1]. COATES DAVID ANDREW, et al. IMIDAZO[1,2-B]PYRIDAZINE IL-17A INHIBITORS. Patent WO2020146194.

IL-17A inhibitor 1 Preparation Products And Raw materials

Raw materials

Preparation Products

IL-17A inhibitor 1 Suppliers

Global( 30)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32470	58
TargetMol Chemicals Inc.	+1-781-999-5354;	support@targetmol.com	United States	39042	58
Zibo Hangyu Biotechnology Development Co., Ltd	+86-0533-2185556 +8615965530500	nickzhang@hangyubiotech.com	China	8497	58
Aladdin Scientific		tp@aladdinsci.com	United States	52923	58
Wuhan Jingkang en Biomedical Technology Co., Ltd	+8613720134139	orders@jknbiochem.com	China	5221	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24964	58
Chuzhou KeMail Chemical Technology Co., Ltd	0550-5196001 15000891977	wj520wjxby@126.com	China	1945	55
Shanghai Lollane Biological Technology Co.,Ltd.	021-52996696，15000506266 15000506266		China	4800	55
ShangHai Angti Biotechnology Co., Ltd.	13764913901	info@angtibio.com	China	4977	55
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9803	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
TargetMol Chemicals Inc.	58
Zibo Hangyu Biotechnology Development Co., Ltd	58
Aladdin Scientific	58
Wuhan Jingkang en Biomedical Technology Co., Ltd	58
TargetMol Chemicals Inc.	58
Chuzhou KeMail Chemical Technology Co., Ltd	55
Shanghai Lollane Biological Technology Co.,Ltd.	55
ShangHai Angti Biotechnology Co., Ltd.	55
Shanghai EFE Biological Technology Co., Ltd.	58

View Lastest Price from IL-17A inhibitor 1 manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-01-15	IL-17A inhibitor 1 2452464-73-0	US $799.00 / mg		99.38%	10g	TargetMol Chemicals Inc.

IL-17A inhibitor 1
2452464-73-0
US $799.00 / mg
99.38%
TargetMol Chemicals Inc.

1,2,5-Oxadiazole-3-carboxamide, N-[(S)-(4,4-difluorocyclohexyl)[7-[(1S)-2-methoxy-1-[(4S)-2-oxo-4-(trifluoromethyl)-1-imidazolidinyl]ethyl]imidazo[1,2-b]pyridazin-2-yl]methyl]-4-methyl- LY-3533028 IL-17A inhibitor 1 inhibit,Inhibitor,Interleukin Related,COPD,Asthma,IL-17A inhibitor 1,IL17A inhibitor 1,IL 17A inhibitor 1 IL-17A inhibitor 1, 10 mM in DMSO LY3509754 2452464-73-0 C24H27F5N8O4