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2-Aminopurine

2-Aminopurine structure

CAS No.: 452-06-2

Chemical Name:: 2-Aminopurine

Synonyms: 9H-Purin-2-amine;sq22451;SQ 22451;SQ 22,451;4-purinamine;iso-Adenine;2-Aminoperin;2-amino-purin;2-AMINOPURINE;4-aminopurine

CBNumber:: CB2853633

Molecular Formula:: C5H5N5

Molecular Weight:: 135.13

MDL Number:: MFCD00005566

MOL File:: 452-06-2.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-07-16 07:06:08

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2-Aminopurine Properties

Melting point	280-282 °C (lit.)
Boiling point	238.81°C (rough estimate)
Density	1.3795 (rough estimate)
refractive index	1.7000 (estimate)
storage temp.	2-8°C
solubility	Aqueous Acid (Slightly), Methanol (Slightly, Heated)
form	Amorphous Powder
pka	8.02±0.20(Predicted)
color	Light beige
biological source	synthetic
Stability	Hygroscopic
InChI	1S/C5H5N5/c6-5-7-1-3-4(10-5)9-2-8-3/h1-2H,(H3,6,7,8,9,10)
InChIKey	MWBWWFOAEOYUST-UHFFFAOYSA-N
SMILES	Nc1ncc2[nH]cnc2n1
CAS DataBase Reference	452-06-2(CAS DataBase Reference)
FDA UNII	O14B3U97FW
NIST Chemistry Reference	Purine, 2-amino-(452-06-2)
UNSPSC Code	41116107
NACRES	NA.51

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302

Precautionary statements

P301+P312+P330

PPE

dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes

Risk Statements

22-36/37/38-20/21/22

Safety Statements

22-36-26

WGK Germany

RTECS

UO7475000

HS Code

29349990

Storage Class

11 - Combustible Solids

Hazard Classifications

Acute Tox. 4 Oral

Toxicity

mmo-sat 100 mg/PLATE MUREAV 111,283,83

NFPA 704

	0
2		0

2-Aminopurine price More Price(77)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	PHR2860	Famciclovir Related Compound E certified reference material, pharmaceutical secondary standard	452-06-2	50MG	$617	2026-04-30	Buy
Sigma-Aldrich	A3509	2-Aminopurine ≥99%	452-06-2	1g	$959	2026-04-30	Buy
Sigma-Aldrich	1269130	Famciclovir Related Compound E United States Pharmacopeia (USP) Reference Standard	452-06-2	25mg	$1080	2026-04-30	Buy
Sigma-Aldrich	5.31619	2-Aminopurine - CAS 452-06-2 - Calbiochem	452-06-2	250MG	$202	2022-05-15	Buy
TCI Chemical	A1111	2-Aminopurine >98.0%(HPLC)(T)	452-06-2	1g	$973	2026-04-30	Buy

Product number	Packaging	Price	Buy
PHR2860	50MG	$617	Buy
A3509	1g	$959	Buy
1269130	25mg	$1080	Buy
5.31619	250MG	$202	Buy
A1111	1g	$973	Buy

2-Aminopurine Chemical Properties,Uses,Production

Chemical Properties

white to light yellow crystal powder

Uses

A probe of structural dynamics and charge transfer in DNA .

Uses

2-Aminopurine has been used to inhibit eukaryotic initiation factor-2α (eIF2α)-phosphorylation of osteoarthritis (OA) chondrocytes.

Uses

A probe of structural dynamicas and charge transfer in DNA

Definition

ChEBI: The parent compound of the 2-aminopurines, comprising a purine core carrying an amino substituent at the 2-position.

Biochem/physiol Actions

2-Aminopurine (2AP) is an analog of guanosine and adenosine, which can base pair with cytosine and thymine. It is used as a fluorescent probe in nucleic acid structure and dynamics. 2-Aminopurine (2-AP) inhibits double-stranded RNA-dependent protein kinase, protein kinase R (PKR).

Safety Profile

Mutation data reported. Whenheated to decomposition it emits toxic fumes of NOx.

2-Aminopurine synthesis

Synthesis of 2-Aminopurine from 6-Chloroguanine

2-Aminopurine Preparation Products And Raw materials

Raw materials

Amipurimycin 6-Chloroguanine

Preparation Products

Famciclovir 2-(Methylthio)-9H-purine 2-Hydroxypyrimidine

2-Aminopurine Suppliers

Global( 243)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006356688 18621169109	market03@meryer.com	China	40202	62
3B Pharmachem (Wuhan) International Co.,Ltd.	18930552037	3bsc@sina.com	China	15813	69
TCI (Shanghai) Development Co., Ltd.	021-67121386	Sales-CN@TCIchemicals.com	China	24512	81
Ark Pharm, Inc.	847-367-3680	sales@arkpharminc.com	United States	1669	56
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61
Capot Chemical Co., Ltd	+86 (0) 571 85 58 67 18		China	18187	66
Nanjing Chemlin Chemical Co., Ltd	025-83697070 13770331960	info@chemlin.com.cn	China	16305	64
Shanghai Hanhong Scientific Co.,Ltd.	021-54306202 13764082696	info@hanhongsci.com	China	42917	64
Chemsky (shanghai) International Co.,Ltd	021-50135380	shchemsky@sina.com	China	15350	60

Supplier	Advantage
J & K SCIENTIFIC LTD.	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	62
3B Pharmachem (Wuhan) International Co.,Ltd.	69
TCI (Shanghai) Development Co., Ltd.	81
Ark Pharm, Inc.	56
Energy Chemical	61
Capot Chemical Co., Ltd	66
Nanjing Chemlin Chemical Co., Ltd	64
Shanghai Hanhong Scientific Co.,Ltd.	64
Chemsky (shanghai) International Co.,Ltd	60

View Lastest Price from 2-Aminopurine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-09-02	2-Aminopurine 452-06-2	$1.10-35.00	1kg	99%		Henan Fengda Chemical Co., Ltd
2026-07-15	2-Aminopurine 452-06-2	$30.00-39.00		99.51%	10g	TargetMol Chemicals Inc.
2022-02-22	2-Aminopurine 452-06-2		1KG	97.9%	100 tons	Honest Joy Holdings Limited

2-Aminopurine
452-06-2
$1.10-35.00
99%
Henan Fengda Chemical Co., Ltd

2-Aminopurine
452-06-2
$30.00-39.00
99.51%
TargetMol Chemicals Inc.

2-Aminopurine
452-06-2
$0.00
97.9%
Honest Joy Holdings Limited

2-Aminopurine Spectrum

2-Aminopurine(452-06-2)MS 2-Aminopurine(452-06-2)¹HNMR 2-Aminopurine(452-06-2)IR 2-Aminopurine(452-06-2)Raman

452-06-2(2-Aminopurine)Related Search:

Triallylamine Glucosamine EC 2.6.1.2 Bis(2-ethylhexyl)amine Purine

Triethanolamine Acetaminophen 2,6-Diaminopurine 2'-deoxyriboside 8-Bromoguanosine 6-Methylthioguanine

6-CHLORO-2-AMINOPURINE 2-Amino-6-chloropurine Riboside Adenine 2-Aminoadenosine 2,6-Diaminopurine sulphate monohydrate

6-Thioguanosine 2-aminopurine-6(1h)-thione,6-mercapto-2-aminopurin 6-[(phenylmethyl)thio]-1H-purin-2-amine

1of4

1H-PURINE-2-AMINE 2-AMINOPURINE, HYDROCHLORIDE 2-AMINOPURINE 1H-Purin-2-amine 4-purinamine 2-amino-purin SQ 22,451 SQ 22451 sq22451 2-Aminopurine;1H-Purine-2-amine; 9H-Purin-2-amine 2-AMINOPURINE FREE BASE 1H-Purin-2-amine (9CI) Purine, 2-amino. iso-Adenine 4-aminopurine 7H-Purin-2-amine 2-Amino-1H-purine 2-Amino-7H-purine 2-Amino-9H-purine 2-Aminopurine,98% 2-Aminoperin 2-Aminopurine, HydrochlorideDiscontinued. See A628886 2-Aminopurine > 2-Aminopurine USP/EP/BP 2-Aminopurine extrapure, 98% Famciclovir USP Related Compound E Famciclovir Impurity 16 ( USP Famciclovir Related Compound E RS) Istradefylline Impurity 27 (Dimethrimol) 2-Aminopurine, 10 mM in DMSO 9H-Purin-2-amine 452-06-2 Biochemicals and Reagents BioChemical Nucleoside Analogs Nucleosides, Nucleotides, Oligonucleotides Heterocycles Biochemistry Nucleobases and their analogs Nucleosides, Nucleotides & Related Reagents Nucleic acids Bases & Related Reagents Nucleotides Nucleoside Analogs Nucleosides, Nucleotides, Oligonucleotides Biochemicals and Reagents PYRIMIDINE Purine Nucleotides and Nucleosides Purines