Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>8-Bromoguanosine

8-Bromoguanosine

8-Bromoguanosine Structure
8-Bromoguanosine structure
CAS No.
4016-63-1
Chemical Name:
8-Bromoguanosine
Synonyms
γ-GT;NAB-1;8-Br-G;8-Br-rG;8-Br-Gr;NSC 79211;NSC 174257;8-Br-Guanosine;8-BROMOGUANOSINE;8-Bromo-D-guanosine
CBNumber:
CB8101198
Molecular Formula:
C10H12BrN5O5
Molecular Weight:
362.14
MDL Number:
MFCD00037985
MOL File:
4016-63-1.mol
MSDS File:
SDS
Last updated:2025-10-11 15:23:28
Product description Number Pack Size Price
8-Bromoguanosine Hydrate >98.0%(HPLC)(T) B4002 1g $42
8-Bromoguanosine Hydrate >98.0%(HPLC)(T) B4002 5g $123
8-Bromoguanosine ≥98% 18152 1g $32
8-Bromoguanosine ≥98% 18152 5g $56
8-Bromoguanosine ≥98% 18152 10g $93
More product size
Request For Quotation

8-Bromoguanosine Properties

Melting point 222°C
Boiling point 774.0±70.0 °C(Predicted)
Density 2.62±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility DMSO, Methanol (Sparingly), Hot Water
form Powder
pka 13.00±0.70(Predicted)
color Off-white
BRN 578725
CAS DataBase Reference 4016-63-1(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS05
Signal word  Danger
Hazard statements  H314-H227-H290
Precautionary statements  P501-P210-P234-P264-P280-P370+P378-P390-P303+P361+P353-P301+P330+P331-P363-P304+P340+P310-P305+P351+P338+P310-P403+P235-P406-P405
Hazard Codes  Xn
Risk Statements  20/21/22-36/37/38
Safety Statements  22-24/25-36-26
WGK Germany  3
HS Code  29389090

8-Bromoguanosine price More Price(40)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical B4002 8-Bromoguanosine Hydrate >98.0%(HPLC)(T) 4016-63-1 1g $42 2022-04-27 Buy
TCI Chemical B4002 8-Bromoguanosine Hydrate >98.0%(HPLC)(T) 4016-63-1 5g $123 2021-12-16 Buy
Cayman Chemical 18152 8-Bromoguanosine ≥98% 4016-63-1 1g $32 2024-03-01 Buy
Cayman Chemical 18152 8-Bromoguanosine ≥98% 4016-63-1 5g $56 2024-03-01 Buy
Cayman Chemical 18152 8-Bromoguanosine ≥98% 4016-63-1 10g $93 2024-03-01 Buy
Product number Packaging Price Buy
B4002 1g $42 Buy
B4002 5g $123 Buy
18152 1g $32 Buy
18152 5g $56 Buy
18152 10g $93 Buy

8-Bromoguanosine Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

8-Bromoguanosine-13C2,15N is an intermediate in the synthesis of 8-Aminoguanosine-13C2,15N (A609877). 8-Aminoguanosine-13C2,15N is an isotopic labelled compound of 8-Aminoguanosine (A609875), which is a potent inhibitor of purine nucleoside phosphorylase.

Definition

ChEBI: 8-Bromoguanosine is a purine nucleoside.

Synthesis

Guanosine

118-00-3

8-Bromoguanosine

4016-63-1

Bromine (0.8 mL, 14.6 mmol) was added dropwise to a suspension of guanosine (4.0 g, 14.4 mmol) in water (100 mL), and the rate of addition was controlled so that the reaction mixture returned to colorless after each addition. The addition of bromine was terminated when the reaction mixture took on a yellowish color due to residual bromine. The colorless solid product was collected by rapid filtration and washed sequentially with 60 mL of cold water and 30 mL of cold acetone. The crude product was recrystallized by dissolving in 150 mL of hot water and subsequently dried under vacuum at 60 °C for 6 hours. Finally, 4.4 g (11.8 mmol, 85% yield) of the target compound 13 was obtained as colorless needle-like crystals with a melting point of 198-200 °C. The NMR data were as follows: 1H NMR (400 MHz, DMSO-d6) δ: 10.82 (1H, s), 6.50 (2H, s), 5.69 (1H, d, J = 6.4 Hz), 5.45 (1H, d, J = 6.0 Hz), 5.09 (1H, d, J = 5.2 Hz), 5.02 (1H, dd, J = 6.0, 11.6 Hz), 4.02 (1H, dd, J = 6.0, 11.6 Hz). 11.6 Hz), 4.92 (1H, t, J = 6.0 Hz), 4.14 (1H, m), 3.86 (1H, m), 3.66 (1H, m), 3.52 (1H, m); 13C NMR (100 MHz, DMSO-d6) δ: 155.5, 153.4, 152.0, 121.2, 117.5, 89.7, 85.8, 70.5, 70.3, 62.0.

References

[1] Photochemistry and Photobiology, 2018, vol. 94, # 4, p. 677 - 684
[2] Nucleosides, Nucleotides and Nucleic Acids, 2012, vol. 31, # 10, p. 707 - 719
[3] Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2001, vol. 40, # 5, p. 382 - 385
[4] Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2002, vol. 41, # 2, p. 379 - 383
[5] Tetrahedron Letters, 2016, vol. 57, # 27-28, p. 2949 - 2953

8-Bromoguanosine Preparation Products And Raw materials

Raw materials

Guanosine Water

Preparation Products

8-Bromoguanosine Suppliers

Global( 224)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		+86-（0）57185586718; +8613336195806 sales@capot.com China 29734 60
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29852 58
Hubei Jusheng Technology Co.,Ltd. 		18871490254 linda@hubeijusheng.com CHINA 28172 58
Nanjing Baifuli Technology Co., Ltd. 		+86-15335185688 sales@unisyn.cn CHINA 332 58
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19552 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
Wuhan Chemwish Technology Co., Ltd 		027-67849912 sales@chemwish.com CHINA 10821 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49975 58
Antai Fine Chemical Technology Co.,Limited 		18503026267 info@antaichem.com CHINA 9636 58
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
ATK CHEMICAL COMPANY LIMITED 		60
career henan chemical co 		58
Hubei Jusheng Technology Co.,Ltd. 		58
Nanjing Baifuli Technology Co., Ltd. 		58
BOC Sciences 		58
Alchem Pharmtech,Inc. 		58
Wuhan Chemwish Technology Co., Ltd 		58
CONIER CHEM AND PHARMA LIMITED 		58
Antai Fine Chemical Technology Co.,Limited 		58

View Lastest Price from 8-Bromoguanosine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
8-Bromoguanosine pictures 2025-10-13 8-Bromoguanosine
4016-63-1
 US $0.00-0.00 / g 25g 98%min 100kgs WUHAN FORTUNA CHEMICAL CO., LTD
8-Bromoguanosine pictures 2025-10-11 8-Bromoguanosine
4016-63-1
 US $29.00 / mg 99.62% 10g TargetMol Chemicals Inc.
8-Bromoguanosine pictures 2025-09-23 8-Bromoguanosine
4016-63-1
 US $0.00-0.00 / G 1G 97% 2000 Shenzhen Nexcon Pharmatechs Ltd.
  • 8-Bromoguanosine pictures
  • 8-Bromoguanosine
    4016-63-1
  • US $0.00-0.00 / g
  • 98%min
  • WUHAN FORTUNA CHEMICAL CO., LTD

8-Bromoguanosine Spectrum

8-Bromoguanosine(4016-63-1)1HNMR

4016-63-1(8-Bromoguanosine)Related Search:

NUCLEOSIDE PHOSPHORYLASE BACTERIAL 6-Thioguanine Adenosine PUROMYCIN AMINONUCLEOSIDE Guanosine 5'-monophosphate disodium salt
Guanine 6-Methoxyguanine 6-Chloropurine ribonucleoside Acyclovir 2-Aminopurine
Guanosine 5'-Guanylic acid 2-Amino-6-chloropurine Riboside 2-BROMO-1-ETHOXYMETHYLIMIDAZOLE Bromine
2-Bromo-1H-imidazole 2-Bromo-1-methyl-1H-imidazole Desciclovir

1of4

8-Bromo-D-guanosine 8-BROMOGUANOSINE, HPLC PURIFIED, 98% PURE WITH HPLC UV CHROMATOGRAM 2-AMINO-8-BROMO-6-HYDROXYPURINE RIBOSIDE 8-BROMOGUANOSINE 8-Bromoguanosine ,98% 8-Br-G 2-aMino-8-broMo-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)oxolan-2-yl]-6,9-dihydro-1H-purin-6-one NAB-1 2-amino-8-bromo-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-3H-purin-6-one B**8-BROMOGUANOSINE NSC 174257 NSC 79211 2-aMino-8-broMo-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one 8-Bromoguanine riboside, 8-Bromo-9-(beta-D-ribofuranosyl)guanine 8-Br-rG 8-Br-Guanosine 8-Br-Gr 8-Bromoguanosine Hydrate> Guanosine, 8-bromo- 8-Bromoguanosine USP/EP/BP γ-GT 4016-63-1 C10H12BrN5O5xH2O C10H12BrN5O5 Nucleoside Analogs Nucleosides, Nucleotides, Oligonucleotides BioChemical Biochemicals and Reagents Pyridines, Pyrimidines, Purines and Pteredines Nucleotides and Nucleosides Bases & Related Reagents Nucleotides