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5-Methyl-2-mercaptobenzothiazole

CAS No.
21303-50-4
Chemical Name:
5-Methyl-2-mercaptobenzothiazole
Synonyms
5-Methylbenzo[d]thiazole-2-thiol;5-Methyl-2-benzothiazolethiol;2-Mercapto-5-methylbenzothiazole;2-Mercapto-5-methyl bezimidazole;5-Methyl-2-mercaptobenzothiazole;5-Methyl-2(3H)-benzothiazolethione;2(3H)-Benzothiazolethione, 5-methyl-;5-Methylbenzo[d]thiazole-2(3h)-thione;5-methyl-3H-1,3-benzothiazole-2-thione;2(3H)-Benzothiazolethione,5-methyl-(9CI)
CBNumber:
CB2969192
Molecular Formula:
C8H7NS2
Molecular Weight:
181.28
MDL Number:
MFCD11044825
MOL File:
21303-50-4.mol
MSDS File:
SDS
Last updated:2026-05-28 00:53:12

5-Methyl-2-mercaptobenzothiazole Properties

Melting point 121 °C
Boiling point 314 °C
Density 1.39
Flash point 144 °C
storage temp. Sealed in dry,Room Temperature
pka 9.60±0.20(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H319
Precautionary statements  P305+P351+P338

5-Methyl-2-mercaptobenzothiazole price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Heterocyclics JR-015093 2-Mercapto-5-methylbenzothiazole 97% 21303-50-4 1g $135 2026-06-05 Buy
Heterocyclics JR-015093 2-Mercapto-5-methylbenzothiazole 97% 21303-50-4 5g $440 2026-06-05 Buy
aablocks AA0072W8 5-Methylbenzo[d]thiazole-2-thiol 98% 21303-50-4 10g $1138 2026-05-28 Buy
ACHEMBLOCK AD288517 5-Methylbenzo[d]thiazole-2(3h)-thione 95% 21303-50-4 1G $230 2026-05-27 Buy
ACHEMBLOCK AD288517 5-Methylbenzo[d]thiazole-2(3h)-thione 95% 21303-50-4 5G $920 2026-05-27 Buy
Product number Packaging Price Buy
JR-015093 1g $135 Buy
JR-015093 5g $440 Buy
AA0072W8 10g $1138 Buy
AD288517 1G $230 Buy
AD288517 5G $920 Buy

5-Methyl-2-mercaptobenzothiazole Chemical Properties, Uses, Production

Synthesis

Carbon disulfide

75-15-0

2-Chloro-5-methylaniline

95-81-8

5-Methyl-2-mercaptobenzothiazole

21303-50-4

Synthesis of 5-methyl-2-mercaptobenzothiazole (10): 2-chloro-5-methylaniline (9, 1.00 g, 7.06 mmol) and potassium carbonate (K2CO3, 2.80 g, 28.2 mmol) were suspended in N,N-dimethylformamide (DMF, 20 mL) under protection of nitrogen. Subsequently, carbon disulfide (CS2, 0.50 mL, 8.50 mmol) was added to the suspension. The reaction mixture was heated and reacted at 150 °C for 16 hours. Upon completion of the reaction, it was cooled to room temperature, the reaction mixture was diluted with deionized water (30 mL) and acidified with 1 N hydrochloric acid (HCl) to a pH of about 1. The resulting precipitate was collected by filtration, washed several times with deionized water, and finally dried under vacuum in the presence of phosphorus pentoxide (P2O5) to afford the target product 5-methyl-2-mercaptobenzothiazole (10, 0.35 g, Yield 27%).

References

[1] Patent: WO2006/122156, 2006, A2. Location in patent: Page/Page column 126

13194-69-9
140-89-6
21303-50-4
Synthesis of 5-Methyl-2-mercaptobenzothiazole from 2-Iodo-5-methylaniline and Potassium ethylxanthate

5-Methyl-2-mercaptobenzothiazole Preparation Products And Raw materials

Global Suppliers ( 36)
Supplier Tel Email Country ProdList Advantage
Beijing Taiya Jie Technology Development Co., Ltd. 021-33690831-8001 13552411790;18616022633 postmaster@tyjchem.cn China 1541 55
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66113011 13913916777 cfzhang@aikonchem.com China 19902 55
Nanjing Duolong Bio-tech Co.,Ltd. 18905173768 52513593@qq.com China 2337 50
Shanghai KaiYuLin pharmaceutical technology co., LTD 021-18721936-595 18721936595 shkylpharma@126.com China 757 55
Cool Pharm, Ltd 021-60455363 18019463053 sales@coolpharm.com China 8455 58
Yancheng Schiemann Biological Technology Co.,Ltd 0515-88280676; 18921872653 sales@ximanbio.com China 1524 56
BioPharmaMatrix,Inc. 0510-86010668 13395169561; sales@biopharmamatrix.com China 4981 55
Zhengzhou Acme Chemical Co., Ltd. 0371-0371-55629727 13323845623 2885676761@qq.com China 9957 58
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Shanghai Qianlai Medical Technology Co., Ltd. 482109853 info@qianlaiyiyao.com China 405 58
2-Mercapto-5-methyl bezimidazole 2(3H)-Benzothiazolethione,5-methyl-(9CI) 5-Methyl-2-mercaptobenzothiazole 5-Methyl-2(3H)-benzothiazolethione 5-Methyl-2-benzothiazolethiol 5-methyl-3H-1,3-benzothiazole-2-thione 2-Mercapto-5-methylbenzothiazole 2(3H)-Benzothiazolethione, 5-methyl- 5-Methylbenzo[d]thiazole-2(3h)-thione 5-Methylbenzo[d]thiazole-2-thiol 21303-50-4 Heterocycles Heterocyclic Compound BENZOTHIAZOLE