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ChemicalBook >> CAS DataBase List >>1-O-Hexadecyl-2-O-ethyl-sn-glycero-3-phosphorylcholine

1-O-Hexadecyl-2-O-ethyl-sn-glycero-3-phosphorylcholine

1-O-Hexadecyl-2-O-ethyl-sn-glycero-3-phosphorylcholine Structure
1-O-Hexadecyl-2-O-ethyl-sn-glycero-3-phosphorylcholine structure
CAS No.
78858-42-1
Chemical Name:
1-O-Hexadecyl-2-O-ethyl-sn-glycero-3-phosphorylcholine
Synonyms
2-O-ETHYL PAF C-16;E-PAF;2-O-ETHYL-PAF;LPHUUVMLQFHHQG-AREMUKBSSA-N;1-O-Hexadecyl-2-O-ethyl-sn-glycero-3-phosphorylcholine;1-O-HEXADECYL-2-O-ETHYL-SN-GLYCERYL-3-PHOSPHORYLCHOLINE
CBNumber:
CB3122934
Molecular Formula:
C26H56NO6P
Molecular Weight:
509.7
MDL Number:
MFCD00210997
MOL File:
78858-42-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:51:33
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1-O-Hexadecyl-2-O-ethyl-sn-glycero-3-phosphorylcholine Properties

solubility DMF: >125 μg/ml; DMSO: <20 μg/ml; Ethanol: >10 mg/ml; PBS pH 7.2: >11 mg/ml
form A lyophilized powder

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501
NFPA 704
0
2 0

1-O-Hexadecyl-2-O-ethyl-sn-glycero-3-phosphorylcholine price More Price(15)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 60925 2-O-ethyl PAF C-16 ≥98% 78858-42-1 1mg $40 2026-04-30 Buy
Cayman Chemical 60925 2-O-ethyl PAF C-16 ≥98% 78858-42-1 5mg $77 2026-04-30 Buy
Cayman Chemical 60925 2-O-ethyl PAF C-16 ≥98% 78858-42-1 10mg $132 2026-04-30 Buy
Cayman Chemical 60925 2-O-ethyl PAF C-16 ≥98% 78858-42-1 25mg $283 2026-04-30 Buy
ChemScene CS-0138064 2-O-Ethyl PAF C-16 78858-42-1 1mg $86 2026-06-04 Buy
Product number Packaging Price Buy
60925 1mg $40 Buy
60925 5mg $77 Buy
60925 10mg $132 Buy
60925 25mg $283 Buy
CS-0138064 1mg $86 Buy

1-O-Hexadecyl-2-O-ethyl-sn-glycero-3-phosphorylcholine Chemical Properties, Uses, Production

Description

2-O-ethyl PAF C-16 is a synthetic PAF analog which contains an ethyl group, attached by an ether linkage, at the sn-2 position. It is a less potent agonist than methylcarbamyl PAF C-16 in the induction of platelet aggregation in both human and rabbit PRP. 2-O-ethyl PAF C-16 causes aggregation of neutrophils in the presence of divalent cations and a desensitization to aggregation in the absence of divalent cations.

Uses

2-O-Ethyl PAF C-16 is a homolog of PAF and a competitive ligand for PAF receptor (Platelet-activating Factor Receptor (PAFR)). 2-O-Ethyl PAF C-16 inhibits the binding of the PAF antagonist WEB 2086 (HY-108634) to the PAF receptor with an IC50 of 21 nM[1].

Definition

ChEBI: 2-O-ethyl PAF C-16 is a glycerophosphocholine and an ether lipid.

References

[1] Aoki Y, et al. A radioreceptor binding assay for platelet-activating factor (PAF) using membranes from CHO cells expressing human PAF receptor. J Immunol Methods. 1995 Oct 26;186(2):225-31. DOI:10.1016/0022-1759(95)00147-3

1-O-Hexadecyl-2-O-ethyl-sn-glycero-3-phosphorylcholine synthesis

116150-00-6
75-50-3
78858-42-1
Synthesis of 1-O-Hexadecyl-2-O-ethyl-sn-glycero-3-phosphorylcholine from 1,3,2-Dioxaphospholane, 2-[2-ethoxy-3-(hexadecyloxy)propoxy]-, 2-oxide, (R)- (9CI) and Trimethylamine

1-O-Hexadecyl-2-O-ethyl-sn-glycero-3-phosphorylcholine Preparation Products And Raw materials

Raw materials

Preparation Products

1-O-Hexadecyl-2-O-ethyl-sn-glycero-3-phosphorylcholine Suppliers

Global Suppliers ( 29)
Supplier Tel Email Country ProdList Advantage
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 400-920-5774 sales@glpbio.cn China 6705 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11123 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8137 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Chengdu Peter-like Biotechnology Co., Ltd. 028-81700200 13308200041 2851167782@qq.com China 10763 58
Shaanxi Didu Pharmaceutical Co., Ltd. 029-81124775 17791530730 1079@dideu.com China 10000 58
Supplier Advantage
Shanghai EFE Biological Technology Co., Ltd. 58
Shanghai Hongye Biotechnology Co. Ltd 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
MedBioPharmaceutical Technology Inc 58
TargetMol Chemicals Inc. 58
Chengdu Peter-like Biotechnology Co., Ltd. 58
Shaanxi Didu Pharmaceutical Co., Ltd. 58

78858-42-1 (1-O-Hexadecyl-2-O-ethyl-sn-glycero-3-phosphorylcholine) Related Search:

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1-O-HEXADECYL-2-O-ETHYL-SN-GLYCERYL-3-PHOSPHORYLCHOLINE 2-O-ETHYL-PAF E-PAF LPHUUVMLQFHHQG-AREMUKBSSA-N 2-O-ETHYL PAF C-16 1-O-Hexadecyl-2-O-ethyl-sn-glycero-3-phosphorylcholine 78858-42-1