RB 101
- CAS No.
- 135949-60-9
- Chemical Name:
- RB 101
- Synonyms
- RB 101;L-Phenylalanine, N-[2-[[[(2S)-2-aMino-4-(Methylthio)butyl]dithio]Methyl]-1-oxo-3-phenylpropyl]-,phenylMethyl ester
- CBNumber:
- CB31349174
- Molecular Formula:
- C31H38N2O3S3
- Molecular Weight:
- 582.85
- MDL Number:
- MFCD00900681
- MOL File:
- 135949-60-9.mol
- MSDS File:
- SDS
| Boiling point | 757.5±60.0 °C(Predicted) |
|---|---|
| Density | 1.210±0.06 g/cm3(Predicted) |
| pka | 13.85±0.46(Predicted) |
| FDA UNII | QN6UQ885QE |
RB 101 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0066890 | RB 101 | 135949-60-9 | 1mg | $1517 | 2026-06-04 | Buy |
| ChemScene | CS-0066890 | RB 101 | 135949-60-9 | 5mg | $4528 | 2026-06-04 | Buy |
| ChemScene | CS-0066890 | RB 101 | 135949-60-9 | 10mg | $4983 | 2026-06-04 | Buy |
| ChemScene | CS-0066890 | RB 101 | 135949-60-9 | 25mg | $7041 | 2026-06-04 | Buy |
| ChemScene | CS-0066890 | RB 101 | 135949-60-9 | 50mg | $9100 | 2026-06-04 | Buy |
RB 101 Chemical Properties,Uses,Production
Uses
RB 101 is an active mixed inhibitor against two enzymes which metabolize the enkephalins neutral endopeptidase and aminopeptidase N. RB 101 has rather long-lasting antinociceptive effects. RB 101 inhibits the in vivo [3H]DPN binding both under basal conditions and after swim stress in mice. RB 101 can be used to determine the precise in vivo localization of enkephalinergic pathways recruited by various stimuli[1][2].
References
[1] Baamonde A, et al. Antidepressant-type effects of endogenous enkephalins protected by systemic RB 101 are mediated by opioid delta and dopamine D1 receptor stimulation. Eur J Pharmacol. 1992 Jun 5;216(2):157-66. DOI:10.1016/0014-2999(92)90356-9
[2] Ruiz-Gayo M, et al. In vivo occupation of mouse brain opioid receptors by endogenous enkephalins: blockade of enkephalin degrading enzymes by RB 101 inhibits [3H]diprenorphine binding. Brain Res. 1992 Feb 7;571(2):306-12. DOI:10.1016/0006-8993(92)90669-z
RB 101 Preparation Products And Raw materials
Raw materials
Preparation Products
RB 101 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou Sage Chemical Co., Ltd. | +86057186818502 13588463833 | info@sagechem.com | China | 10265 | 58 |
| Shanghai HuanChuan Industry Co.,Ltd. | 021-61478794 | sales@hcshhai.com | China | 9781 | 50 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| TargetMol Chemicals Inc. | 13564774135 | marketing@targetmol.com | United States | 19950 | 58 |
| Supplier | Advantage |
|---|---|
| Hangzhou Sage Chemical Co., Ltd. | 58 |
| Shanghai HuanChuan Industry Co.,Ltd. | 50 |
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
