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QR-6401
- CAS No.
- 2845096-18-4
- Chemical Name:
- QR-6401
- Synonyms
- QR-6401
- CBNumber:
- CB313731561
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
- TDS File:
- TDS
Last updated:2026-07-27 17:00:41
QR-6401 Chemical Properties, Uses, Production
Uses
QR-6401 is an orally active and selective macrocyclic CDK2 inhibitor with IC50 values of 0.37, 10, 22, 34 and 45 nM for CDK2/E1, CDK9/T1, CDK1/A2, CDK6/D3 and CDK4/D1, respectively. QR-6401 has potent antitumor activity in an OVCAR3 ovarian cancer xenograft model. QR-6401 has the potential to be used in the study of cancer[1].
References
[1] Yu Y, et al. Accelerated Discovery of Macrocyclic CDK2 Inhibitor QR-6401 by Generative Models and Structure-Based Drug Design. ACS Med Chem Lett. 2023 Feb 8;14(3):297-304. DOI:10.1021/acsmedchemlett.2c00515
QR-6401 Preparation Products And Raw materials
Raw materials
Preparation Products
QR-6401 Suppliers
Global Suppliers ( 3)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nantong QuanYi Biotechnology Co., Ltd | 0513-66337626 18051384581 | sales@chemhifuture.com | China | 5985 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| TargetMol Chemicals Inc. | 13564774135 | marketing@targetmol.com | United States | 19950 | 58 |
| Supplier | Advantage |
|---|---|
| Nantong QuanYi Biotechnology Co., Ltd | 58 |
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
QR-6401
2845096-18-4
