deramciclane
- CAS No.
- 120444-72-6
- Chemical Name:
- deramciclane
- Synonyms
- Deramciclane fumarate
- CBNumber:
- CB31400613
- Molecular Formula:
- C20H31NO.C4H4O4
- Molecular Weight:
- 417.543
- MDL Number:
- MFCD00873171
- MOL File:
- 120444-72-6.mol
- MSDS File:
- SDS
| Melting point | 210-213° |
|---|---|
| alpha | 43620 -88.0° ± 1 (c = 0.4 in DMSO) |
| pka | 9.61(at 25℃) |
| FDA UNII | W1183TY0EE |
deramciclane Chemical Properties, Uses, Production
Uses
Deramciclane fumarate is an antagonist of 5-HT Receptor. Deramciclane fumarate is an inverse agonist of 5-HT2C Receptor with an IC50 of 168 nM. Deramciclane fumarate also decreases basal phosphoinositide hydrolysis[1][2].
References
[1] Plvimki EP, et al. eramciclane, a putative anxiolytic drug, is a serotonin 5-HT2C receptor inverse agonist but fails to induce 5-HT2C receptor down-regulation. Psychopharmacology (Berl). 1998 Mar;136(2):99-104. DOI:10.1007/s002130050544
[2] Kriinen TM, et al. Comparison of the effects of deramciclane, ritanserin and buspirone on extracellular dopamine and its metabolites in striatum and nucleus accumbens of freely moving rats. Basic Clin Pharmacol Toxicol. 2008 Jan;102(1):50-8. DOI:10.1111/j.1742-7843.2007.00145.x
deramciclane Preparation Products And Raw materials
Raw materials
Preparation Products
deramciclane Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29873 | 58 |
| TargetMol Chemicals Inc. | 13564774135 | marketing@targetmol.com | United States | 19950 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
View Latest Price from deramciclane manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-11 | Deramciclane fumarate
120444-72-6
|
$1520.00-2500.00 | 10g | TargetMol Chemicals Inc. |
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- Deramciclane fumarate
120444-72-6
- $1520.00-2500.00
- TargetMol Chemicals Inc.
