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HSD17B13-IN-99

CAS No.
2849338-46-9
Chemical Name:
HSD17B13-IN-99
Synonyms
HSD17B13-IN-99;2-Pyridinecarboxamide, N-[3,4-dihydro-3-[2-(2-methoxyphenyl)ethyl]-4-oxo-5-quinazolinyl]-5-hydroxy-6-(trifluoromethyl)-
CBNumber:
CB314270102
Molecular Formula:
C24H19F3N4O4
Molecular Weight:
484.43
MDL Number:
MOL File:
2849338-46-9.mol
Last updated:2025-04-17 18:22:24

HSD17B13-IN-99 Properties

Density 1.42±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
pka 10.50±0.20(predicted)

HSD17B13-IN-99 Chemical Properties, Uses, Production

Uses

HSD17B13-IN-99 (Compound 6) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of < 0.1 μM for estradiol. HSD17B13-IN-99 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD or NASH, as well as drug-induced liver injury (DILI)[1].

References

[1] Joshua Odingo, et al. Hydroxypyridine hsd17b13 inhibitors and uses thereof. U.S., WO2022216626. 2022-10-13.

HSD17B13-IN-99 Preparation Products And Raw materials

Raw materials

Preparation Products

HSD17B13-IN-99 Suppliers

Global Suppliers ( 1)
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Supplier Advantage
TargetMol Chemicals Inc. 58
HSD17B13-IN-99 2-Pyridinecarboxamide, N-[3,4-dihydro-3-[2-(2-methoxyphenyl)ethyl]-4-oxo-5-quinazolinyl]-5-hydroxy-6-(trifluoromethyl)- 2849338-46-9