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SHP2-IN-21

SHP2-IN-21 Structure
SHP2-IN-21 structure
CAS No.
2941499-08-5
Chemical Name:
SHP2-IN-21
Synonyms
SHP2-IN-21;Spiro[6H-cyclopenta[b]pyridine-6,4′-piperidin]-5-amine, 1′-[7-(4-fluoro-1H-indol-7-yl)-6-methylpyrazolo[1,5-a]pyrazin-4-yl]-5,7-dihydro-, (5S)-
CBNumber:
CB314290885
Molecular Formula:
C27H26FN7
Molecular Weight:
467.54
MDL Number:
MOL File:
2941499-08-5.mol
Last updated:2026-05-11 16:31:51
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SHP2-IN-21 Properties

Density 1.500±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka 15.609±0.30(predicted)

SHP2-IN-21 Chemical Properties, Uses, Production

Uses

SHP2-IN-21 (compound 208) is a SHP2 inhibitor with an IC50 value of 3 nM. SHP2-IN-21 can be used for glioblastoma research[1].

References

[1] Sabnis RW. Novel Pyrazolopyrazine Compounds as SHP2 Inhibitors for Treating Glioblastoma. ACS Med Chem Lett. 2023 Sep 19;14(10):1336-1337. DOI:10.1021/acsmedchemlett.3c00393

SHP2-IN-21 Preparation Products And Raw materials

Raw materials

Preparation Products

SHP2-IN-21 Suppliers

Global Suppliers ( 2)
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
TargetMol Chemicals Inc. 13564774135 marketing@targetmol.com United States 19950 58
Supplier Advantage
TargetMol Chemicals Inc. 58
TargetMol Chemicals Inc. 58

View Latest Price from SHP2-IN-21 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
SHP2-IN-21 pictures 2026-05-11 SHP2-IN-21
2941499-08-5
 10g TargetMol Chemicals Inc.

2941499-08-5 (SHP2-IN-21) Related Search:

Sodium Stibogluconate SHP836 1H-Isoindole-1,3(2H)-dione, 4-[[14-[4-[[[1-[6-amino-5-(2,3-dichlorophenyl)-2-pyrazinyl]-4-methyl-4-piperidinyl]amino]methyl]-1H-1,2,3-triazol-1-yl]-3,6,9,12-tetraoxatetradec-1-yl]amino]-2-(2,6-dioxo-3-piperidinyl)- 4-Piperidinamine, 1-[3-(2,3-dichlorophenyl)-1H-pyrazolo[3,4-b]pyrazin-6-yl]-4-methyl- Methanone, [4-[[(1R)-1-[3-amino-5-(trifluoromethyl)phenyl]ethyl]amino]-2-chloro-5,7-dihydro-6H-pyrrolo[3,4-d]pyrimidin-6-yl](tetrahydro-4-methoxy-2H-pyran-4-yl)-
2-Pyrazinemethanol, 6-[(2-amino-3-chloro-4-pyridinyl)thio]-3-[(3S,4S)-4-amino-3-methyl-2-oxa-8-azaspiro[4.5]dec-8-yl]-5-methyl-

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SHP2-IN-21 Spiro[6H-cyclopenta[b]pyridine-6,4′-piperidin]-5-amine, 1′-[7-(4-fluoro-1H-indol-7-yl)-6-methylpyrazolo[1,5-a]pyrazin-4-yl]-5,7-dihydro-, (5S)- 2941499-08-5