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3-(4-Bromo-2,6-dichlorophenyl)piperidine-2,6-dione

3-(4-Bromo-2,6-dichlorophenyl)piperidine-2,6-dione structure

CAS No.: 3036607-19-6

Chemical Name:: 3-(4-Bromo-2,6-dichlorophenyl)piperidine-2,6-dione

Synonyms: CRBN ligand-148;3-(4-Bromo-2,6-dichlorophenyl)piperidine-2,6-dione;2,6-Piperidinedione, 3-(4-bromo-2,6-dichlorophenyl)-

CBNumber:: CB314434328

Molecular Formula:: C11H8BrCl2NO2

Molecular Weight:: 337

MDL Number:

MOL File:: 3036607-19-6.mol

Last updated:2025-05-19 13:47:43

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3-(4-Bromo-2,6-dichlorophenyl)piperidine-2,6-dione Properties

Boiling point	441.855±45.00 °C(Press: 760.00 Torr)(predicted)
Density	1.687±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka	10.706±0.40(predicted)

3-(4-Bromo-2,6-dichlorophenyl)piperidine-2,6-dione price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
ACHEMBLOCK	AD284162	3-(4-Bromo-2,6-dichlorophenyl)piperidine-2,6-dione 95%	3036607-19-6	100MG	$385	2026-05-27	Buy
ACHEMBLOCK	AD284162	3-(4-Bromo-2,6-dichlorophenyl)piperidine-2,6-dione 95%	3036607-19-6	250MG	$650	2026-05-27	Buy
ACHEMBLOCK	AD284162	3-(4-Bromo-2,6-dichlorophenyl)piperidine-2,6-dione 95%	3036607-19-6	1G	$1750	2026-05-27	Buy

Product number	Packaging	Price	Buy
AD284162	100MG	$385	Buy
AD284162	250MG	$650	Buy
AD284162	1G	$1750	Buy

3-(4-Bromo-2,6-dichlorophenyl)piperidine-2,6-dione Chemical Properties, Uses, Production

Uses

CRBN ligand-148 is a CRBN-type E3 ubiquitin ligase ligand that can be used to prepare PROTAC.

IC 50

Cereblon

References

[1] Mileti N, et al. Workflow for E3 Ligase Ligand Validation for PROTAC Development. ACS Chem Biol. 2025 Feb 21;20(2):507-521. DOI:10.1021/acschembio.4c00812

3-(4-Bromo-2,6-dichlorophenyl)piperidine-2,6-dione Preparation Products And Raw materials

Raw materials

Preparation Products

3-(4-Bromo-2,6-dichlorophenyl)piperidine-2,6-dione Suppliers

Global Suppliers ( 11)

Supplier	Tel	Email	Country	ProdList	Advantage
ChemOrigin Pharm	15026428026 19002516454	ChemOrigin@126.com	China	1585	58
Jinan Ruisi Pharmaceutical Technology Co., LTD	0531-0531-69900633 19963472814	changyuan20@163.com	China	9938	58
Birdo (Shanghai) Medical Technology Co., Ltd.	021-58099077-8041 18601625411	sales@birdotech.com	China	9382	58
Wuhan Yuxiang Medical Technology Co., Ltd.	13971275651	sales@whyxpharma.com	China	1831	58
Shanghai Haohong Scientific Co., Ltd.	400-8210725 4008210725	malulu@leyan.com	China	39319	58
Shaoyuan Technology (Shanghai) Co., Ltd.	021-50795510 4000665055	marketing@accelachem.com	China	9985	58
Aikon International Limited	025-58859352 18651614124	2881516338@qq.com	China	9968	58
Tianjin Qige Technology Co., Ltd.	13012205621	304306732@qq.com	China	297	58
Zibo Guangyun Chemical Co., Ltd	18105338618	zbgyhx@126.com	China	57	58
Xi'an Huarui Zhiyuan Biotechnology Co., Ltd.	18014474522	3487723181@qq.com	China	1166	58

Supplier	Advantage
ChemOrigin Pharm	58
Jinan Ruisi Pharmaceutical Technology Co., LTD	58
Birdo (Shanghai) Medical Technology Co., Ltd.	58
Wuhan Yuxiang Medical Technology Co., Ltd.	58
Shanghai Haohong Scientific Co., Ltd.	58
Shaoyuan Technology (Shanghai) Co., Ltd.	58
Aikon International Limited	58
Tianjin Qige Technology Co., Ltd.	58
Zibo Guangyun Chemical Co., Ltd	58
Xi'an Huarui Zhiyuan Biotechnology Co., Ltd.	58

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3-(4-Bromo-2,6-dichlorophenyl)piperidine-2,6-dione CRBN ligand-148 2,6-Piperidinedione, 3-(4-bromo-2,6-dichlorophenyl)- 3036607-19-6