2-Methyl-1,4-benzenedicarboxylic acid
- CAS No.
- 5156-01-4
- Chemical Name:
- 2-Methyl-1,4-benzenedicarboxylic acid
- Synonyms
- DK7272;0/4/56;Nsc20693;Fluralaner-025;Fluralaner Impurity 46;Methylterephthalic acid;5-Methylterephthalic acid;2-Methylterephthalic 2-methylterephthalic acid;Terephthalic acid, methyl-
- CBNumber:
- CB31456175
- Molecular Formula:
- C9H8O4
- Molecular Weight:
- 180.16
- MDL Number:
- MFCD09835103
- MOL File:
- 5156-01-4.mol
- MSDS File:
- SDS
| Melting point | 323-325 °C |
|---|---|
| Boiling point | 388.2±30.0 °C(Predicted) |
| Density | 1.377 |
| Flash point | 202.8℃ |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 3.38±0.25(Predicted) |
| Appearance | Off-white to yellow Solid |
| InChI | InChI=1S/C9H8O4/c1-5-4-6(8(10)11)2-3-7(5)9(12)13/h2-4H,1H3,(H,10,11)(H,12,13) |
| InChIKey | UFMBOFGKHIXOTA-UHFFFAOYSA-N |
| SMILES | C1(C(O)=O)=CC=C(C(O)=O)C=C1C |
| UNSPSC Code | 12352103 |
| NACRES | NA.23 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302+H312+H332-H315-H319-H335 |
| Precautionary statements | P280 |
| WGK Germany | WGK 3 |
| HS Code | 29173990 |
| Storage Class | 11 - Combustible Solids |
2-Methyl-1,4-benzenedicarboxylic acid price More Price(36)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SIK2103-10 | 2-Methylterephthalicacid-H2MT/H2BDC-Me ≥97% | 5156-01-4 | 1G | $594 | 2026-04-30 | Buy |
| Sigma-Aldrich | SIK2103-10 | 2-Methylterephthalicacid-H2MT/H2BDC-Me ≥97% | 5156-01-4 | 250MG | $174 | 2023-06-20 | Buy |
| TCI Chemical | M3640 | 2-Methylterephthalic Acid min. 95.0 % | 5156-01-4 | 1G | $101 | 2026-04-30 | Buy |
| Apolloscientific | OR51802 | 2-Methylterephthalic acid 97% | 5156-01-4 | 250mg | $25 | 2026-06-04 | Buy |
| Apolloscientific | OR51802 | 2-Methylterephthalic acid 97% | 5156-01-4 | 1g | $30 | 2026-06-04 | Buy |
2-Methyl-1,4-benzenedicarboxylic acid Chemical Properties, Uses, Production
Preparation
The specific preparation method is as follows: using 2-Methyl-1,4-benzenedicarboxylic acid as raw material, the following steps are included in sequence: 1) Esterification: under the catalysis of concentrated sulfuric acid, 2-Methyl-1,4-benzenedicarboxylic acid and methanol undergo esterification reaction at 80℃ for 8h~12h, and the material ratio of 2-Methyl-1,4-benzenedicarboxylic acid to methanol is 1:10; 2) Water absorption: using anhydrous copper sulfate as a water absorbent, anhydrous copper sulfate is added to the above mixture, and the weight ratio of 2-Methyl-1,4-benzenedicarboxylic acid to anhydrous copper sulfate is 20:17~1:1; 3) Extraction: using dichloromethane as an extractant, the lower organic phase is separated; 4) Recrystallization: the obtained crude dimethyl terephthalate is recrystallized in petroleum ether to obtain dimethyl terephthalate.
Application
2-Methyl-1,4-phthalic acid can be used as an intermediate in pharmaceutical and chemical synthesis, such as in the synthesis of dimethyl 2-methyl terephthalate. Dimethyl 2-methyl terephthalate is an important compound in the synthesis of vinyl terephthalic acid-based chitosan liquid crystal polymers. Currently, most methods employ acid-catalyzed synthesis, resulting in low yields of only about 33% and significant raw material losses. Since dimethyl 2-methyl terephthalate is a necessary intermediate in the synthesis of vinyl terephthalic acid-based chitosan liquid crystal polymers, improving its yield is crucial. However, most acid-catalyzed esterification reactions suffer from low conversion rates. In this reaction, methanol serves as both a reagent and a solvent. Due to its low boiling point, a suitable dehydrating agent cannot be found for use in oil-water separators. Therefore, based on existing research, anhydrous copper sulfate powder, which has strong hygroscopic properties, is added. At 80°C, anhydrous copper sulfate can bind three water molecules, thereby improving the esterification conversion rate. The results of infrared IR and nuclear magnetic resonance (NMR) analyses of the obtained products confirm the correctness of the synthesized compound, laying the foundation for the next step of large-scale synthesis of vinyl terephthalic acid-based chitosan-type liquid crystal polymers.
2-Methyl-1,4-benzenedicarboxylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Zhengzhou Alpha Chemical Co. LTD | 0371-53732842 13383863444 | 3838551451@qq.com | China | 9997 | 58 |
| ZHIWE CHEMTECH CO LTD | 021-20221225 13917446399 | zwchem@163.com | China | 525 | 61 |
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9407 | 55 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16305 | 64 |
| Shanghai AmasPharm Co., Ltd. | 021-54540637 18621091017 | sales@amaspharm.com | China | 787 | 62 |
| ZhengZhou HuaWen Chemical Co.Ltd | 0370-2785118 17550508557 | 675141927@qq.com | China | 3201 | 55 |
| Shanghai ZaiQi Bio-Tech Co., Ltd. | 021-54824098, 021-37212705 021-37212706, 13391256916 | sales@chemzq.com | China | 569 | 55 |
| Nanjing Norris-Pharm Technology Co., Ltd | 13901585132 | sales@norris-pharm.com | China | 8869 | 55 |
| Chemsoon Co., Ltd | 021-51987688-803 18916626396 | info@chemsoon.com | China | 267 | 55 |
View Latest Price from 2-Methyl-1,4-benzenedicarboxylic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-25 | 2-Methyl-1,4-benzenedicarboxylic acid
5156-01-4
|
$1.60-6.60 | 1kg | 99% | 100kg | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |
 |
2025-12-24 | 2-Methyl-1,4-benzenedicarboxylic acid
5156-01-4
|
1KG | 99.0% | 1000 tons | Shaanxi Dideu Medichem Co. Ltd | ||
 |
2020-11-16 | 2-Methyl-1,4-benzenedicarboxylic acid
5156-01-4
|
$30.00 | 25Kg/Bag | 99% | 20 Tons | Longyan Tianhua Biological Technology Co., Ltd |
-
- 2-Methyl-1,4-benzenedicarboxylic acid
5156-01-4
- $1.60-6.60
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-
- 2-Methyl-1,4-benzenedicarboxylic acid
5156-01-4
- $0.10
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
-
- 2-Methyl-1,4-benzenedicarboxylic acid
5156-01-4
- $30.00
- 99%
- Longyan Tianhua Biological Technology Co., Ltd
