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ChemicalBook >> CAS DataBase List >>4-[4-[2-(4-hydroxy-3,5-ditert-butyl-phenyl)sulfanylpropan-2-ylsulfanyl]-2,6-ditert-butyl-phenoxy]-4-oxo-butanoic acid

4-[4-[2-(4-hydroxy-3,5-ditert-butyl-phenyl)sulfanylpropan-2-ylsulfanyl]-2,6-ditert-butyl-phenoxy]-4-oxo-butanoic acid

4-[4-[2-(4-hydroxy-3,5-ditert-butyl-phenyl)sulfanylpropan-2-ylsulfanyl]-2,6-ditert-butyl-phenoxy]-4-oxo-butanoic acid Structure
4-[4-[2-(4-hydroxy-3,5-ditert-butyl-phenyl)sulfanylpropan-2-ylsulfanyl]-2,6-ditert-butyl-phenoxy]-4-oxo-butanoic acid structure
CAS No.
216167-82-7
Chemical Name:
4-[4-[2-(4-hydroxy-3,5-ditert-butyl-phenyl)sulfanylpropan-2-ylsulfanyl]-2,6-ditert-butyl-phenoxy]-4-oxo-butanoic acid
Synonyms
SUCCINOBUCOL;AGI 1067;AGZ-1067;AGI 1067 ，S6420;Flunixin Monomer;SUCCINOBUCOL, >98%;Probucol Monosuccinate;Succinobucol(AGI 1067);Succinobucol, 10 mM in DMSO;Probucol monosuccinate, >98%
CBNumber:
CB31458896
Molecular Formula:
C35H52O5S2
Molecular Weight:
616.91
MDL Number:
MFCD08690469
MOL File:
216167-82-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-14 16:49:18
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4-[4-[2-(4-hydroxy-3,5-ditert-butyl-phenyl)sulfanylpropan-2-ylsulfanyl]-2,6-ditert-butyl-phenoxy]-4-oxo-butanoic acid Properties

Melting point 139 - 142°C
Boiling point 659.5±55.0 °C(Predicted)
Density 1.13±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility Chloroform (Slightly), Methanol (Slightly)
pka 4.27±0.17(Predicted)
form Solid
color White to Light Yellow
InChIKey RKSMVPNZHBRNNS-UHFFFAOYSA-N
SMILES OC1=C(C(C)(C)C)C=C(SC(C)(C)SC2=CC(C(C)(C)C)=C(OC(CCC(O)=O)=O)C(C(C)(C)C)=C2)C=C1C(C)(C)C
FDA UNII J1J54V24R4
UNSPSC Code 12352200
NACRES NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
WGK Germany  WGK 3
Storage Class 11 - Combustible Solids

4-[4-[2-(4-hydroxy-3,5-ditert-butyl-phenyl)sulfanylpropan-2-ylsulfanyl]-2,6-ditert-butyl-phenoxy]-4-oxo-butanoic acid price More Price(35)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 30886 Succinobucol ≥95% 216167-82-7 10mg $91 2026-04-30 Buy
Cayman Chemical 30886 Succinobucol ≥95% 216167-82-7 25mg $202 2026-04-30 Buy
Cayman Chemical 30886 Succinobucol ≥95% 216167-82-7 50mg $355 2026-04-30 Buy
Cayman Chemical 30886 Succinobucol ≥95% 216167-82-7 100mg $662 2026-04-30 Buy
Biosynth FS27918 Succinobucol 216167-82-7 10mg $150 2026-06-04 Buy
Product number Packaging Price Buy
30886 10mg $91 Buy
30886 25mg $202 Buy
30886 50mg $355 Buy
30886 100mg $662 Buy
FS27918 10mg $150 Buy

4-[4-[2-(4-hydroxy-3,5-ditert-butyl-phenyl)sulfanylpropan-2-ylsulfanyl]-2,6-ditert-butyl-phenoxy]-4-oxo-butanoic acid Chemical Properties, Uses, Production

Uses

An antioxidant and anti-inflammatory.

Definition

ChEBI: Succinobucol is a benzoate ester and a member of phenols.

Biological Activity

Succinobucol is a metabolically stable derivative of the antioxidant drug probucol th at poses a distinct pharmacological from. Succinobucol is an orally active vascular protectant th at exhibits antiatherosclerotic properties in multiple animal models and in humans. It inhibits the release of proinflammatory cytokines, TNF-a, IL-1b, and IL-6 in hPBMC activated by LPS.

in vivo

Succinobucol (50, 100, and 150 mg/kg, i.v.) has no significant effect on either heart rate or MAP, but the blood removed 15 minutes after the final injection of succinobucol shows significantly less aggregation in response to collagen at both 5 μg/mL and 20 μg/mL in rats[1]. Succinobucol (40 mg/kg) by tail injection significantly reduces the average number of metastatic nodules in lung metastatic breast cancer mice[3].

4-[4-[2-(4-hydroxy-3,5-ditert-butyl-phenyl)sulfanylpropan-2-ylsulfanyl]-2,6-ditert-butyl-phenoxy]-4-oxo-butanoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

4-[4-[2-(4-hydroxy-3,5-ditert-butyl-phenyl)sulfanylpropan-2-ylsulfanyl]-2,6-ditert-butyl-phenoxy]-4-oxo-butanoic acid Suppliers

Global Suppliers ( 90)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
LGM Pharma 1-(800)-881-8210 inquiries@lgmpharma.com United States 2110 70
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
MedChemexpress LLC 021-58955995 sales@medchemexpress.cn United States 4853 58
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Shanghai JiYi Biotechnology Co. Ltd. 13621943973 sales@shjiyipharmatech.com China 1166 55
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Shanghai Chaolan Chemical Technology Center QQ：65489617 13301690235 Sales@ATKchemical.com China 9729 58
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Medi-tech Bioscientific Co., Ltd. 0519-83246372 13585352506 China 1838 58
Supplier Advantage
J & K SCIENTIFIC LTD. 76
LGM Pharma 70
Chemsky（shanghai）International Co.,Ltd. 50
MedChemexpress LLC 58
Bide Pharmatech Ltd. 60
Shanghai JiYi Biotechnology Co. Ltd. 55
Shanghai YuanYe Biotechnology Co., Ltd. 60
Shanghai Chaolan Chemical Technology Center 58
Amadis Chemical Company Limited 58
Medi-tech Bioscientific Co., Ltd. 58

View Latest Price from 4-[4-[2-(4-hydroxy-3,5-ditert-butyl-phenyl)sulfanylpropan-2-ylsulfanyl]-2,6-ditert-butyl-phenoxy]-4-oxo-butanoic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Succinobucol pictures 2026-07-14 Succinobucol
216167-82-7
 $30.00-98.00 98.80% 10g TargetMol Chemicals Inc.
4-[4-[2-(4-hydroxy-3,5-ditert-butyl-phenyl)sulfanylpropan-2-ylsulfanyl]-2,6-ditert-butyl-phenoxy]-4-oxo-butanoic acid pictures 2026-07-10 4-[4-[2-(4-hydroxy-3,5-ditert-butyl-phenyl)sulfanylpropan-2-ylsulfanyl]-2,6-ditert-butyl-phenoxy]-4-oxo-butanoic acid
216167-82-7
 1KG 98% 1000kg Shaanxi Dideu New Materials Co. Ltd
  • Succinobucol pictures
  • Succinobucol
    216167-82-7
  • $30.00-98.00
  • 98.80%
  • TargetMol Chemicals Inc.

4-[4-[2-(4-hydroxy-3,5-ditert-butyl-phenyl)sulfanylpropan-2-ylsulfanyl]-2,6-ditert-butyl-phenoxy]-4-oxo-butanoic acid Spectrum

4-[4-[2-(4-hydroxy-3,5-ditert-butyl-phenyl)sulfanylpropan-2-ylsulfanyl]-2,6-ditert-butyl-phenoxy]-4-oxo-butanoic acid(216167-82-7)1HNMR

216167-82-7 (4-[4-[2-(4-hydroxy-3,5-ditert-butyl-phenyl)sulfanylpropan-2-ylsulfanyl]-2,6-ditert-butyl-phenoxy]-4-oxo-butanoic acid) Related Search:

Probucol ELSIBUCOL 2-Bromopyridine 4-[4-[2-(4-hydroxy-3,5-ditert-butyl-phenyl)sulfanylpropan-2-ylsulfanyl]-2,6-ditert-butyl-phenoxy]-4-oxo-butanoic acid Bis(phenylthio)methane
Probucol Disuccinate

1of2

AGI-1067;PROBUCOL MONOSUCCINATE Probucol monosuccinate, >98% SUCCINOBUCOL, >98% AGZ-1067 AGZ1067. Probucol monosuccinae SUCCINOBUCOL; AGI-1067; AGZ-1067; AGI1067; AGZ1067. PROBUCOL MONOSUCCINAE Succinobucol(AGI 1067) Butanedioic Acid 1-[4-[[1-[[3,5-Bis(1,1-diMethylethyl)-4-hydroxyphenyl]thio]-1-Methylethyl]thio]-2,6-bis(1,1-diMethylethyl)phenyl] Ester Probucol Monosuccinate AGI 1067 4-(2,6-di-tert-butyl-4-(2-(3,5-di-tert-butyl-4-hydroxyphenylthio)propan-2-ylthio)phenoxy)-4-oxobutanoic acid 2H-1-Benzopyran-2-one,6-bromo-3,7-dihydro- Inhibitor,inhibit,AGI 1067,Succinobucol,Reactive Oxygen Species,AGI1067 Flunixin Monomer 4-[2,6-ditert-butyl-4-[2-(3,5-ditert-butyl-4-hydroxyphenyl)sulfanylpropan-2-ylsulfanyl]phenoxy]-4-oxobutanoic acid Succinobucol, 10 mM in DMSO AGI 1067 ，S6420 SUCCINOBUCOL 216167-82-7 Aromatics Intermediates & Fine Chemicals Pharmaceuticals Sulfur & Selenium Compounds