ChemicalBook > Product Catalog >API >Circulatory system drugs >Lipid regulating drugs >4-[4-[2-(4-hydroxy-3,5-ditert-butyl-phenyl)sulfanylpropan-2-ylsulfanyl]-2,6-ditert-butyl-phenoxy]-4-oxo-butanoic acid

4-[4-[2-(4-hydroxy-3,5-ditert-butyl-phenyl)sulfanylpropan-2-ylsulfanyl]-2,6-ditert-butyl-phenoxy]-4-oxo-butanoic acid

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4-[4-[2-(4-hydroxy-3,5-ditert-butyl-phenyl)sulfanylpropan-2-ylsulfanyl]-2,6-ditert-butyl-phenoxy]-4-oxo-butanoic acid Suppliers list
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Products Intro: Product Name:AGI 1067
CAS:216167-82-7
Purity:98% Package:10MG;50MG;100MG,1G,5G,10G.100G
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Products Intro: Product Name:Succinobucol
CAS:216167-82-7
Purity:0.98 Package:10g, 1kg
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Products Intro: Product Name:Succinobucol
CAS:216167-82-7
Purity:99.96% Package:5mg;30USD|10mg;48USD|25mg;98USD Remarks:REAGENT;FOR LABORATORY USE ONLY
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Products Intro: Product Name:AGI 1067
CAS:216167-82-7
Purity:99% Package:5KG;1KG Remarks:AGI 1067
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Products Intro: Product Name:Succinobucol
CAS:216167-82-7
Purity:98% Package:5mg Remarks:V3733

4-[4-[2-(4-hydroxy-3,5-ditert-butyl-phenyl)sulfanylpropan-2-ylsulfanyl]-2,6-ditert-butyl-phenoxy]-4-oxo-butanoic acid manufacturers

  • Succinobucol
  • Succinobucol pictures
  • $30.00
  • 2026-07-14
  • CAS:216167-82-7
  • Purity: 98.80%
  • Supply Ability: 10g
4-[4-[2-(4-hydroxy-3,5-ditert-butyl-phenyl)sulfanylpropan-2-ylsulfanyl]-2,6-ditert-butyl-phenoxy]-4-oxo-butanoic acid Basic information
Product Name:4-[4-[2-(4-hydroxy-3,5-ditert-butyl-phenyl)sulfanylpropan-2-ylsulfanyl]-2,6-ditert-butyl-phenoxy]-4-oxo-butanoic acid
Synonyms:AGI-1067;PROBUCOL MONOSUCCINATE;Probucol monosuccinate, >98%;SUCCINOBUCOL, >98%;AGZ-1067;AGZ1067. Probucol monosuccinae;SUCCINOBUCOL; AGI-1067; AGZ-1067; AGI1067; AGZ1067. PROBUCOL MONOSUCCINAE;Succinobucol(AGI 1067);Butanedioic Acid 1-[4-[[1-[[3,5-Bis(1,1-diMethylethyl)-4-hydroxyphenyl]thio]-1-Methylethyl]thio]-2,6-bis(1,1-diMethylethyl)phenyl] Ester
CAS:216167-82-7
MF:C35H52O5S2
MW:616.91
EINECS:
Product Categories:Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds
Mol File:216167-82-7.mol
4-[4-[2-(4-hydroxy-3,5-ditert-butyl-phenyl)sulfanylpropan-2-ylsulfanyl]-2,6-ditert-butyl-phenoxy]-4-oxo-butanoic acid Structure
4-[4-[2-(4-hydroxy-3,5-ditert-butyl-phenyl)sulfanylpropan-2-ylsulfanyl]-2,6-ditert-butyl-phenoxy]-4-oxo-butanoic acid Chemical Properties
Melting point 139 - 142°C
Boiling point 659.5±55.0 °C(Predicted)
density 1.13±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility Chloroform (Slightly), Methanol (Slightly)
pka4.27±0.17(Predicted)
form Solid
color White to Light Yellow
InChIKeyRKSMVPNZHBRNNS-UHFFFAOYSA-N
SMILESOC1=C(C(C)(C)C)C=C(SC(C)(C)SC2=CC(C(C)(C)C)=C(OC(CCC(O)=O)=O)C(C(C)(C)C)=C2)C=C1C(C)(C)C
Safety Information
WGK Germany WGK 3
Storage Class11 - Combustible Solids
MSDS Information
4-[4-[2-(4-hydroxy-3,5-ditert-butyl-phenyl)sulfanylpropan-2-ylsulfanyl]-2,6-ditert-butyl-phenoxy]-4-oxo-butanoic acid Usage And Synthesis
UsesAn antioxidant and anti-inflammatory.
DefinitionChEBI: Succinobucol is a benzoate ester and a member of phenols.
Biological ActivitySuccinobucol is a metabolically stable derivative of the antioxidant drug probucol th at poses a distinct pharmacological from. Succinobucol is an orally active vascular protectant th at exhibits antiatherosclerotic properties in multiple animal models and in humans. It inhibits the release of proinflammatory cytokines, TNF-a, IL-1b, and IL-6 in hPBMC activated by LPS.
in vivo

Succinobucol (50, 100, and 150 mg/kg, i.v.) has no significant effect on either heart rate or MAP, but the blood removed 15 minutes after the final injection of succinobucol shows significantly less aggregation in response to collagen at both 5 μg/mL and 20 μg/mL in rats[1]. Succinobucol (40 mg/kg) by tail injection significantly reduces the average number of metastatic nodules in lung metastatic breast cancer mice[3].

4-[4-[2-(4-hydroxy-3,5-ditert-butyl-phenyl)sulfanylpropan-2-ylsulfanyl]-2,6-ditert-butyl-phenoxy]-4-oxo-butanoic acid Preparation Products And Raw materials
Tag:4-[4-[2-(4-hydroxy-3,5-ditert-butyl-phenyl)sulfanylpropan-2-ylsulfanyl]-2,6-ditert-butyl-phenoxy]-4-oxo-butanoic acid(216167-82-7) Related Product Information
BIS(PHENYLTHIO)METHANE Probucol ELSIBUCOL 2-Bromopyridine 4-[4-[2-(4-hydroxy-3,5-ditert-butyl-phenyl)sulfanylpropan-2-ylsulfanyl]-2,6-ditert-butyl-phenoxy]-4-oxo-butanoic acid Probucol Disuccinate