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ChemicalBook >> CAS DataBase List >>6-Chloro-1,2,3,4-tetrahydroquinoline

6-Chloro-1,2,3,4-tetrahydroquinoline

6-Chloro-1,2,3,4-tetrahydroquinoline Structure
6-Chloro-1,2,3,4-tetrahydroquinoline structure
CAS No.
49716-18-9
Chemical Name:
6-Chloro-1,2,3,4-tetrahydroquinoline
Synonyms
6-Chloro-1,2,3,4-tetrahydroquinoline;Quinoline, 6-chloro-1,2,3,4-tetrahydro-
CBNumber:
CB31497987
Molecular Formula:
C9H10ClN
Molecular Weight:
167.64
MDL Number:
MFCD09034966
MOL File:
49716-18-9.mol
MSDS File:
SDS
Last updated:2026-09-12 18:51:41
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6-Chloro-1,2,3,4-tetrahydroquinoline Properties

Melting point 41 °C
Boiling point 125-127 °C(Press: 3 Torr)
Density 1.162±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
pka 4.43±0.20(Predicted)
Appearance Light brown to brown Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H303-H319-H335-H315
Precautionary statements  P312-P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
HazardClass  IRRITANT
HS Code  2933499090

6-Chloro-1,2,3,4-tetrahydroquinoline price More Price(49)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific OR951504 6-Chloro-1,2,3,4-tetrahydroquinoline 98% 49716-18-9 100mg $21 2026-06-04 Buy
Apolloscientific OR951504 6-Chloro-1,2,3,4-tetrahydroquinoline 98% 49716-18-9 250mg $24 2026-06-04 Buy
Apolloscientific OR951504 6-Chloro-1,2,3,4-tetrahydroquinoline 98% 49716-18-9 1g $56 2026-06-04 Buy
Apolloscientific OR951504 6-Chloro-1,2,3,4-tetrahydroquinoline 98% 49716-18-9 5g $192 2026-06-04 Buy
Apolloscientific OR951504 6-Chloro-1,2,3,4-tetrahydroquinoline 98% 49716-18-9 25g $777 2026-06-04 Buy
Product number Packaging Price Buy
OR951504 100mg $21 Buy
OR951504 250mg $24 Buy
OR951504 1g $56 Buy
OR951504 5g $192 Buy
OR951504 25g $777 Buy

6-Chloro-1,2,3,4-tetrahydroquinoline Chemical Properties,Uses,Production

Uses

6-Chloro-1,2,3,4-tetrahydroquinoline (cas# 49716-18-9) is a compound useful in organic synthesis.

Synthesis Reference(s)

Tetrahedron Letters, 28, p. 77, 1987 DOI: 10.1016/S0040-4039(00)95653-3

Synthesis

6-CHLOROQUINOLINE

612-57-7

6-CHLORO-1,2,3,4-TETRAHYDROQUINOLINE

49716-18-9

GENERAL STEPS: PdNPore (2.7 mg, 5 mol%) was dissolved in acetonitrile (5 mL) and 6-chloroquinoline (81.8 mg, 0.5 mmol) was added. The reaction mixture was placed in a magnetic stirrer at 30 °C for 16 h under hydrogen atmosphere (5 bar). After completion of the reaction, it was purified by column chromatography (silica gel, 200-300 mesh, ethyl acetate as eluent) to afford 6-chloro-1,2,3,4-tetrahydroquinoline (69.57 mg, 83% yield).

References

[1] Bioorganic and Medicinal Chemistry, 2008, vol. 16, # 17, p. 7956 - 7967
[2] Angewandte Chemie - International Edition, 2016, vol. 55, # 50, p. 15656 - 15661
[3] Angew. Chem., 2016, vol. 128, # 50, p. 15885 - 15890,6
[4] Organic Letters, 2013, vol. 15, # 7, p. 1484 - 1487
[5] Chemical Communications, 2013, vol. 49, # 63, p. 7052 - 7054

6-Chloro-1,2,3,4-tetrahydroquinoline Preparation Products And Raw materials

Raw materials

6-Chloroquinoline Acetonitrile Hydrogen Palladium

Preparation Products

6-Chloro-1,2,3,4-tetrahydroquinoline Suppliers

Global( 97)Suppliers
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Tongchuang Pharma(Suzhou). Co., Ltd. 0512-63263366 18912765016 tongtf110@sina.com China 984 62
Shanghai Topbiochem Technology Co., Ltd +86-21-60341587 sales@topbiochem.com China 6166 58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66113011 13913916777 cfzhang@aikonchem.com China 19902 55
SuZhou ShiYa Biopharmaceuticals, Inc. 86(512)5235 8471 17715136450 sales@shiyabiopharm.com China 4167 58
9ding chemical ( Shanghai) Limited 4009209199 sales@9dingchem.com China 18201 56
SynAsst Chemical. 021-60343070 China 12731 55
Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd. +86-28-85122536 85324413 market@astatech.cn China 8016 55
Shijiazhuang Lickon PharmaTech Co., Ltd. 031185291771 13832391721 yaofeng2005@163.com China 947 58
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Supplier Advantage
J & K SCIENTIFIC LTD. 76
Tongchuang Pharma(Suzhou). Co., Ltd. 62
Shanghai Topbiochem Technology Co., Ltd 58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 55
SuZhou ShiYa Biopharmaceuticals, Inc. 58
9ding chemical ( Shanghai) Limited 56
SynAsst Chemical. 55
Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd. 55
Shijiazhuang Lickon PharmaTech Co., Ltd. 58
Bide Pharmatech Ltd. 60

6-Chloro-1,2,3,4-tetrahydroquinoline Spectrum

6-CHLORO-1,2,3,4-TETRAHYDROQUINOLINE(49716-18-9)1HNMR

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Quinoline, 6-chloro-1,2,3,4-tetrahydro- 6-Chloro-1,2,3,4-tetrahydroquinoline 49716-18-9