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2-Methoxy-3-isobutyl pyrazine

2-Methoxy-3-isobutyl pyrazine structure

CAS No.: 24683-00-9

Chemical Name:: 2-Methoxy-3-isobutyl pyrazine

Synonyms: ipmp;2-ISOBUTYL-3-METHOXYPYRAZINE;2-METHOXY-3-ISOBUTYLPYRAZINE;3-ISOBUTYL-2-METHOXYPYRAZINE;Pyrazine, 2-methoxy-3-(2-methylpropyl)-;FEMA 3132;Femano.3132;FEMA NUMBER 3132;Thymol Impurity?37;2-Methoxy-3-isobutyl

CBNumber:: CB3154674

Molecular Formula:: C9H14N2O

Molecular Weight:: 166.22

MDL Number:: MFCD00006128

MOL File:: 24683-00-9.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 01:00:26

Product description	Number	Pack Size	Price
2-Isobutyl-3-methoxypyrazine ≥99%, FG	W313203	1 each	$91.5
2-Isobutyl-3-methoxypyrazine ≥99%, FG	W313203	100g	$570
2-Isobutyl-3-methoxypyrazine ≥99%, FG	W313203	500g	$2100
2-Isobutyl-3-methoxypyrazine ≥99%, FG	W313203	1kg	$3560
2-Isobutyl-3-methoxypyrazine solution certified reference material	47528-U	1mL	$42.1
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2-Methoxy-3-isobutyl pyrazine Properties

Boiling point	294.44°C (rough estimate)
Density	0.99 g/mL at 25 °C(lit.)
refractive index	n20/D 1.49(lit.)
FEMA	3132 \| 2-ISOBUTYL-3-METHOXYPYRAZINE
FLAVIS Number	14.043 \| 2-Isobutyl-3-methoxypyrazine
Flash point	176 °F
storage temp.	room temp
form	Liquid
pka	0.80±0.10(Predicted)
Specific Gravity	0.995
color	Clear colorless
Odor	green-pepper odor FCT 2000
Odor Type	green
biological source	synthetic
JECFA Number	792
Henry's Law Constant	1.7×10^-1 mol/(m³Pa) at 25℃, Karl et al. (2003)
Cosmetics Ingredients Functions	PERFUMING
InChI	1S/C9H14N2O/c1-7(2)6-8-9(12-3)11-5-4-10-8/h4-5,7H,6H2,1-3H3
InChIKey	UXFSPRAGHGMRSQ-UHFFFAOYSA-N
SMILES	COc1nccnc1CC(C)C
LogP	2.62
CAS DataBase Reference	24683-00-9(CAS DataBase Reference)
Substances Added to Food (formerly EAFUS)	2-ISOBUTYL-3-METHOXYPYRAZINE
FDA UNII	S327O0T12O
NIST Chemistry Reference	Pyrazine, 2-methoxy-3-(2-methylpropyl)-(24683-00-9)
EPA Substance Registry System	Pyrazine, 2-methoxy-3-(2-methylpropyl)- (24683-00-9)
UNSPSC Code	77101502
NACRES	NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

target organs

Respiratory system

PPE

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

Hazard Codes

Xi,T,F

Risk Statements

36/37/38-39/23/24/25-23/24/25-11

Safety Statements

26-36-24/25-45-36/37-16-7

RIDADR

UN 1230 3/PG 2

WGK Germany

TSCA

TSCA listed

HS Code

29339900

Storage Class

10 - Combustible liquids

Hazard Classifications

Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

NFPA 704

	1
2		0

2-Methoxy-3-isobutyl pyrazine price More Price(61)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	W313203	2-Isobutyl-3-methoxypyrazine ≥99%, FG	24683-00-9	1 each	$91.5	2026-04-30	Buy
Sigma-Aldrich	W313203	2-Isobutyl-3-methoxypyrazine ≥99%, FG	24683-00-9	100g	$570	2026-04-30	Buy
Sigma-Aldrich	W313203	2-Isobutyl-3-methoxypyrazine ≥99%, FG	24683-00-9	500g	$2100	2026-04-30	Buy
Sigma-Aldrich	W313203	2-Isobutyl-3-methoxypyrazine ≥99%, FG	24683-00-9	1kg	$3560	2026-04-30	Buy
Sigma-Aldrich	47528-U	2-Isobutyl-3-methoxypyrazine solution certified reference material	24683-00-9	1mL	$42.1	2026-04-30	Buy

Product number	Packaging	Price	Buy
W313203	1 each	$91.5	Buy
W313203	100g	$570	Buy
W313203	500g	$2100	Buy
W313203	1kg	$3560	Buy
47528-U	1mL	$42.1	Buy

2-Methoxy-3-isobutyl pyrazine Chemical Properties,Uses,Production

Description

2-Isobutyl-3-methoxypyrazine has an extremely powerful odor with a reported threshold value of 2 parts per trillion in water. Diluted water solutions exhibit a characteristic odor of green bell peppers. May be synthesized by condensation of leucine amide with glyoxal, followed by methylation with CH2H2.

Chemical Properties

2-Isobutyl-3-methoxypyrazine has a green bell pepper, green pea odor. Diluted water solutions of this compound exhibit a characteristic odor of green bell peppers.

Chemical Properties

CLEAR COLOURLESS LIQUID

Occurrence

Reported present in green bell pepper, coffee, galbanum oil, potato products, peas, grapes, lettuce, sherry, white wine, cocoa, beans, beetroot, passion fruit and okra.

Uses

2-Isobutyl-3-methoxypyrazine has been employed as a model odorant molecule during an electrochemical assay for the detection of odorant molecules based on a rat odorant-binding protein (rOBP3).

Preparation

By condensation of leucine amide with glyoxal followed by methylation with CH2H2

Aroma threshold values

Detection: 2 ppt to 10 ppb

General Description

2-Isobutyl-3-methoxypyrazine, a potent bell-pepper odourant, has been found to bind to cow olfactory mucosa homogenate.

2-Methoxy-3-isobutyl pyrazine synthesis

Synthesis of 2-Methoxy-3-isobutyl pyrazine from 3-ISOBUTYL-1H-PYRAZIN-2-ONE

2-Methoxy-3-isobutyl pyrazine Preparation Products And Raw materials

Raw materials

Glyoxal Methanol

Preparation Products

2-Methoxy-3-isobutyl pyrazine Suppliers

Global( 325)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Chuanghai Biotechnology Co,.LTD	+86-86-13131129325 +8613131129325	sales1@chuanghaibio.com	China	5228	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20122	58
JINING XINHE CHEMICAL CO., LTD	+8615318402391	sales@xinhepharma.com	China	809	58
Hebei Zhuanglai Chemical Trading Co Ltd	+86-16264648883	niki@zlchemi.com	China	7245	58
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29815	58
Jinan Finer Chemical Co., Ltd	+86-531-88989536 +86-15508631887	sales@finerchem.com	China	2950	58
Xiamen AmoyChem Co., Ltd	+86-86-5926051114 +8615060885618	sales@amoychem.com	China	6366	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19936	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49979	58

Supplier	Advantage
Hebei Chuanghai Biotechnology Co,.LTD	58
Henan Fengda Chemical Co., Ltd	58
JINING XINHE CHEMICAL CO., LTD	58
Hebei Zhuanglai Chemical Trading Co Ltd	58
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Jinan Finer Chemical Co., Ltd	58
Xiamen AmoyChem Co., Ltd	58
BOC Sciences	58
CONIER CHEM AND PHARMA LIMITED	58

View Lastest Price from 2-Methoxy-3-isobutyl pyrazine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-05-28	2-Methoxy-3-Isobutyl Pyrazine 24683-00-9	$2.00-5.00	1KG	99%	10000kg	Hebei Chuanghai Biotechnology Co,.LTD
2026-05-11	2-Isobutyl-3-methoxypyrazine 24683-00-9	$31.00		98.31%	10g	TargetMol Chemicals Inc.
2025-12-01	2-Methoxy-3-isobutyl pyrazine 24683-00-9		1KG	98.0%	10000KGS	Shaanxi Dideu New Materials Co. Ltd

2-Methoxy-3-Isobutyl Pyrazine
24683-00-9
$2.00-5.00
99%
Hebei Chuanghai Biotechnology Co,.LTD

2-Isobutyl-3-methoxypyrazine
24683-00-9
$31.00
98.31%
TargetMol Chemicals Inc.

2-Methoxy-3-isobutyl pyrazine
24683-00-9
98.0%
Shaanxi Dideu New Materials Co. Ltd

2-Methoxy-3-isobutyl pyrazine Spectrum

2-Methoxy-3-isobutyl pyrazine(24683-00-9)¹HNMR 2-Methoxy-3-isobutyl pyrazine(24683-00-9)IR 2-Methoxy-3-isobutyl pyrazine(24683-00-9)FT-IR

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2-ISOBUTYL-3(5/6)-METHOXYPYRAZINE 2-methoxy-3-(2-methyl-propyl) pyrazine 2-methoxy-3-(2-methylpropyl)-pyrazin 2-methoxy-3-(2-methylpropyl)-Pyrazine 3-methoxy-2-isobutylpyrazine Pyrazine, 2-(2-methylpropyl)-3-methoxy Pyrazine, 2-isobutyl-3-methoxy Pyrazine, 3-methoxy-2-(2-methylpropyl) 2-Isobutyl-3-methoxypyrazine Odor Standard 2-ISOBUTYL-3-(5)-METHOXYPYRAZINE FEMA 3132 FEMA NUMBER 3132 2-methoxy-3-iosobutylpyrazine 2-ISOBUTYL-3-METHOXYPYRAZINE 99+% 2-Isobutyl-3-methoxypyrazine, tech., cont. 20% 2-isobutyl-6-methoxypyrazine, 80% isobutylmethoxypyrazine,2-isobutyl-3-methoxypyrazine 2-isobutyl-3-methoxypyrazine solution Femano.3132 3-Methoxy-2-(2-methylpropyl)pyrazine 2-Isobutyl-3-methoxypyrazine,80%,tech., cont.20% 2-isobutyl-6-methoxypyrazine 2-METHOXY-3-ISOBUTYL PYRAZINE FEMA NO.3132 2-Isobutyl-3-Methoxypyrazine, 99% 1GR 2-Methoxy-3-isobutyl 2-Methoxy-3-isobutyl pyrazine SynonyMs 3-Isobutyl-2-Methoxypyrazine 2-Isobutyl-3-Methoxypyrazine 99% 2-Isobutyl-3-methoxypyrazineSolution,100mg/L,5x1ml 2-Isobutyl-3-methoxypyrazine Odor Standard@1000 μg/mL in Methanol 2-Isobutyl-3-methoxypyrazine> 2-Isobutyl-3-methoxypyrazineSolution,100mg/L,1ml 2-Isobutyl-3-methoxypyrazine (IBMP) 2-Methoxy-3-isobutyl pyrazine USP/EP/BP Thymol Impurity?37 C14394700 2-Isobutyl-3-methoxypyrazine XA14394700ME2-Isobutyl-3-methoxypyrazinE100 μg 2-Isobutyl-3-methoxypyrazine in Methanol 2-Isobutyl-3-methoxypyrazine 100 μg/mL in Methanol 2-ISOBUTYL-3-METHOXYPYRAZINE 2-METHOXY-3-ISOBUTYLPYRAZINE 3-ISOBUTYL-2-METHOXYPYRAZINE ipmp Pyrazine, 2-methoxy-3-(2-methylpropyl)- 24683-00-9 2468-00-9 24683-00-3 C9H14N2O Mono- & Polyalkylpyrazines Pyrazines Alkoxypyrazines Building Blocks Heterocyclic Building Blocks 500 Series Drinking Water Methods Drinking WaterEPA Odor Standards Chromatography Environmental Standards Alphabetical Listings Flavors and Fragrances I-L