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Bis(4-fluorophenyl)-methanone

Bis(4-fluorophenyl)-methanone structure

CAS No.: 345-92-6

Chemical Name:: Bis(4-fluorophenyl)-methanone

Synonyms: 4,4-DIFLUOROBENZOPHENONE;BDF;Difluorobenzophenone;4,4’-difluoro-benzophenon;BIS(4-FLUOROPHENYL) KETONE;Bis(4-fluorophenyl)-;4,4' -difluorophenone;p-Fluorophenyl ketone;-Difluorobenzophenone;LABOTEST-BB LT00159767

CBNumber:: CB3179589

Molecular Formula:: C13H8F2O

Molecular Weight:: 218.2

MDL Number:: MFCD00000353

MOL File:: 345-92-6.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-24 14:58:52

Product description	Number	Pack Size	Price
4,4′-Difluorobenzophenone 99%	115495	25g	$116
4,4′-Difluorobenzophenone Pharmaceutical Secondary Standard; Certified Reference Material	PHR2117	200mg	$165
4,4'-Difluorobenzophenone >99.0%(GC)	D1797	25g	$31
4,4'-Difluorobenzophenone >99.0%(GC)	D1797	100g	$63
4,4′-Difluorobenzophenone 99%	115495	100g	$245
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Bis(4-fluorophenyl)-methanone Properties

Melting point	102-105 °C (lit.)
Boiling point	137°C (3 torr)
Density	1.2543 (estimate)
vapor pressure	0.005Pa at 20℃
Flash point	170-172°C/10mm
storage temp.	Sealed in dry,Room Temperature
solubility	Insoluble in water
form	Crystalline Powder
color	White to slightly yellow
Water Solubility	8.757mg/L at 20℃
BRN	516231
InChI	1S/C13H8F2O/c14-11-5-1-9(2-6-11)13(16)10-3-7-12(15)8-4-10/h1-8H
InChIKey	LSQARZALBDFYQZ-UHFFFAOYSA-N
SMILES	Fc1ccc(cc1)C(=O)c2ccc(F)cc2
LogP	3.37 at 20℃
CAS DataBase Reference	345-92-6(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	88BNC11B9C
NIST Chemistry Reference	4,4'-Difluorobenzophenone(345-92-6)
EPA Substance Registry System	4,4'-Difluorobenzophenone (345-92-6)
UNSPSC Code	77101502
NACRES	NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07,GHS09

Signal word

Warning

Hazard statements

H302-H315-H319-H335-H411

Precautionary statements

P273-P301+P312+P330-P302+P352-P305+P351+P338

target organs

Respiratory system

PPE

dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes

Xi,N,Xn

Risk Statements

36/37/38-51/53-22

Safety Statements

26-37/39-36-61

RIDADR

UN 3077 9 / PGIII

WGK Germany

RTECS

DJ0685000

TSCA

TSCA listed

HazardClass

IRRITANT

HS Code

29143990

Storage Class

13 - Non Combustible Solids

Hazard Classifications

Acute Tox. 4 Oral
Aquatic Chronic 2
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

NFPA 704

	0
2		0

Bis(4-fluorophenyl)-methanone price More Price(41)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	115495	4,4′-Difluorobenzophenone 99%	345-92-6	25g	$116	2026-03-19	Buy
Sigma-Aldrich	PHR2117	4,4′-Difluorobenzophenone Pharmaceutical Secondary Standard; Certified Reference Material	345-92-6	200mg	$165	2026-03-19	Buy
TCI Chemical	D1797	4,4'-Difluorobenzophenone >99.0%(GC)	345-92-6	25g	$31	2026-03-19	Buy
TCI Chemical	D1797	4,4'-Difluorobenzophenone >99.0%(GC)	345-92-6	100g	$63	2026-03-19	Buy
Sigma-Aldrich	115495	4,4′-Difluorobenzophenone 99%	345-92-6	100g	$245	2026-03-19	Buy

Product number	Packaging	Price	Buy
115495	25g	$116	Buy
PHR2117	200mg	$165	Buy
D1797	25g	$31	Buy
D1797	100g	$63	Buy
115495	100g	$245	Buy

Bis(4-fluorophenyl)-methanone Chemical Properties,Uses,Production

Chemical Properties

white to slightly yellow crystalline powder

Uses

4,4′-Difluorobenzophenone has been used in the study of thermal stability, water uptake and proton conductivity of carboxylated, carboxylated/sulfonated, and crosslinked membranes.

Synthesis Reference(s)

Journal of the American Chemical Society, 90, p. 540, 1968 DOI: 10.1021/ja01004a087

General Description

4,4′-Difluorobenzophenone is typically used as a starting material for the preparation of polyetheretherketone (PEEK) polymer, a high-temperature thermoplastic, which finds wide use in dentistry as well as in automotive, oil industries, etc.

Synthesis

Mix 200g of fluorobenzene with 65g of anhydrous aluminum trichloride, cool to 0-5, add 100g of p-fluorotrichloromethylbenzene dropwise reaction for 20min, get 4,4'-difluorophenyl dichloromethane;

Add 4,4'-difluorophenyl dichloromethane to 600g of water mixing, heating To the azeotropic temperature at the same time recycling fluorobenzene 140g, reaction 5h, cooling to room temperature, filtration, drying to get light yellow solid crude 102g, using 200g methanol recrystallization, filtration, washing, drying, to get the melting point of 107-108 white crystals 92g, the purity of gas chromatography analysis of 99.9%, the yield is 90%. Detected by 1H-NMR: 7.28 (4H, t, hydrogen adjacent to the fluorine on the benzene ring); 7.81 (4H, m, hydrogen adjacent to the carbonyl on the benzene ring), which is consistent with the structure of 4,4'-difluorobenzophenone.

Bis(4-fluorophenyl)-methanone synthesis

Synthesis of Bis(4-fluorophenyl)-methanone from Benzene, 1,1'-(azidomethylene)bis[4-fluoro-

Bis(4-fluorophenyl)-methanone Preparation Products And Raw materials

Raw materials

Fluorobenzene (2-Naphtyl)tributylstannane 4-FLUORO-(TRI-N-BUTYLSTANNYL)BENZENE 4,4'-Difluorodiphenylmethane 4,4'-Difluorobenzhydrol

4,4'-Dichlorobenzophenone 4-Fluorobenzoyl chloride Dimethyl sulfone 4-FLUOROBENZENEDIAZONIUM TETRAFLUOROBORATE 4-Fluorobenzaldehyde

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Preparation Products

(4-(4-[BIS(4-FLUOROPHENYL)METHYL]PIPERAZIN-1-YL)PHENYL)METHANOL 1,1'-(4-CHLOROBUTYLIDENE)BIS(4-FLUOROBENZENE) 4-FLUORO-4'-NITROBENZOPHENONE BIS-(4-FLUORO-PHENYL)-PHENYL-METHANOL 1,1-BIS(4-FLUOROPHENYL)-1-BUTENE

Bis(4-fluorophenyl)-methanone Suppliers

Global( 709)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
BEYOND INDUSTRIES (CHINA) LIMITED	+86-21-52699951; +8613917686115	sales@beyondindustriesgroup.com	China	699	58
Chengdu Yuanda Chemical Co., Ltd	28-85356300 +8618980937689	sales@ydachem.com	CHINA	94	58
Hebei baicao biology science and technology co., ltd	+86-19131911055 +8617824879454	zhang@hbbocao.com	China	1029	58
SINO HIGH(CHINA)CO.,LTD.	+86-2558392388 +86-13914336446	chang@sinohighchem.com	China	34	58
Weifang Dayoo Biochemical Co., Ltd.,	+undefined13305362020	sales@dayoochemical.com	China	21	58
Ningbo Banco Chemical Technology Co., Ltd.	+86-15827200700	sales@bancochemical.com	China	487	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615350571055	Sibel@chuanghaibio.com	China	8738	58
Shaanxi Dideu Medichem Co. Ltd	+86-029-81138252 +86-173 9270 1263	1057@dideu.com	China	4000	58
Hebei Yanxi Chemical Co., Ltd.	+8618531123677	faithe@yan-xi.com	China	5853	58
RongNa Biotechnology Co.,Ltd	+86-86-13583358881 +8618560316533	Brad@rongnabiotech.com	China	3364	58

Supplier	Advantage
BEYOND INDUSTRIES (CHINA) LIMITED	58
Chengdu Yuanda Chemical Co., Ltd	58
Hebei baicao biology science and technology co., ltd	58
SINO HIGH(CHINA)CO.,LTD.	58
Weifang Dayoo Biochemical Co., Ltd.,	58
Ningbo Banco Chemical Technology Co., Ltd.	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Shaanxi Dideu Medichem Co. Ltd	58
Hebei Yanxi Chemical Co., Ltd.	58
RongNa Biotechnology Co.,Ltd	58

Bis(4-fluorophenyl)-methanone for enhancing the stability and safety of nickel-rich cathode based cells
Bis(4-fluorophenyl)-methanone is used for enhancing the stability and safety of Ni rich lithium ion batteries.
Feb 25，2025

View Lastest Price from Bis(4-fluorophenyl)-methanone manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-04-30	Bis(4-fluorophenyl)-methanone 345-92-6	US $0.00 / KG	1KG	98%min	30tons/month	WUHAN FORTUNA CHEMICAL CO., LTD
2026-04-30	Bis(4-fluorophenyl)-methanone 345-92-6	US $100.00-75.00 / g	1g	99%	5000	HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
2026-04-30	4,4'-Difluorobenzophenone 345-92-6	US $0.00 / KG	1KG	99%	200mt	Jinan Finer Chemical Co., Ltd

Bis(4-fluorophenyl)-methanone
345-92-6
US $0.00 / KG
98%min
WUHAN FORTUNA CHEMICAL CO., LTD

Bis(4-fluorophenyl)-methanone
345-92-6
US $100.00-75.00 / g
99%
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD

4,4'-Difluorobenzophenone
345-92-6
US $0.00 / KG
99%
Jinan Finer Chemical Co., Ltd

Bis(4-fluorophenyl)-methanone Spectrum

Bis(4-fluorophenyl)-methanone(345-92-6)MS Bis(4-fluorophenyl)-methanone(345-92-6)¹HNMR Bis(4-fluorophenyl)-methanone(345-92-6)¹³CNMR Bis(4-fluorophenyl)-methanone(345-92-6)IR1 Bis(4-fluorophenyl)-methanone(345-92-6)IR2 Bis(4-fluorophenyl)-methanone(345-92-6)Raman

345-92-6(Bis(4-fluorophenyl)-methanone)Related Search:

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Benzophenone, 4,4'-difluoro- bis(4-fluorophenyl)-methanon Bis(p-fluorophenyl) ketone bis(p-fluorophenyl)ketone Di-p-fluorophenyl ketone di-p-fluorophenylketone Methanone, bis(4-fluorophenyl)- p,p’-difluorobenzophenone p,p'-Difluorobenzophenone 4,4'-Difluorbenzophenone DI(4-FLUOROPHENYL)METHANONE LABOTEST-BB LT00159767 BIS-(4-FLUORO-PHENYL)-METHANONE 4,4'-Dddifluorobenzophenone 4,4'-Difluorobnzophenone 4,4'-Difluorobenzophenone/Bis(4-Fluorophenyl)Methanone 4,4'-Difluorobenzophenone, 98+% 4,4''-DIFLURO BENZOPHENONE 4,4'-Difluorobenzophenone99% Flunarizine Impurity 10 4'-Difluorobenzophenone (4,4-difluoro-1-cyclohexa-1,5-dienyl)-phenylmethanone Bis(4-fluorophenyl)-methanone 345-92-6 4,4''-DIFLUOROBENZOPHENONEFLUNARIZINE 4, 4 - two fluorine diphenyl ketone Difluorobenzophenone 4,4'- twofluorine twoBenzophenone 4,4'-Difluorobenzophenone, 97+% 1,1'-Carbonylbis(4-fluorobenzene) 4,4'-Carbonylbis(1-fluorobenzene) 4,4'-Carbonylbis(fluorobenzene) Bis(4-fluorophenyl)- 4.4'-Difluarobenzophonone 4,4'-Difluorobenzophenone≥ 99% (GC) 1,1-di(p-fluorophenyl)-ketone 4,4'-Difluorobenzophenone, 99%, for synthesis 4,4'-Difluorobenzophenone > 4,4' -difluorophenone High Quality 4, 4′-Difluorobenzophenone p-Fluorophenyl ketone -Difluorobenzophenone Benzophenone,4,4'-difluoro-Chemicalbook 4,4'-Difluorobenzophenone 4,4'-difluoro-benzophenon 4,4′-Difluorobenzophenone, CAS 345-92-6 4,4’-difluoro-benzophenon 4,4-DIFLUOROBENZOPHENONE BIS(4-FLUOROPHENYL) KETONE BDF 345-92-6 3450-92-6 C13H8F2O Benzophenones (for High-Performance Polymer Research) Reagent for High-Performance Polymer Research C13 to C14 Carbonyl Compounds Building Blocks Organic Building Blocks