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2'-Deoxyguanosine

2'-Deoxyguanosine Structure
2'-Deoxyguanosine structure
CAS No.
961-07-9
Chemical Name:
2'-Deoxyguanosine
Synonyms
2;DG;deoxyguanosine;Desoxyguanosine;Guanine deoxyriboside;Guanine deoxy nucleoside;2 '- deoxyguanosine;2-amino-9-[4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-3H-purin-6-one;2-Amino-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,9-dihydro-6H-purin-6-one;2'-dG
CBNumber:
CB3209022
Molecular Formula:
C10H13N5O4
Molecular Weight:
267.24
MDL Number:
MFCD00080300
MOL File:
961-07-9.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-08-25 20:17:46
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2'-Deoxyguanosine Properties

Melting point 300 °C
Boiling point 410.43°C (rough estimate)
Density 1.3382 (rough estimate)
refractive index -42 ° (C=0.2, 1mol/L NaOH)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility NH4OH 1 M: 50 mg/mL, clear to very faintly turbid, yellow to brown
form powder
pka 9+-.0.20(Predicted)
color White to Off-white
PH 2.37;9.33
optical activity Consistent with structure
Water Solubility Slightly soluble in water.
λmax 255 (pH 1)
BRN 39814
Major Application pharmaceutical
Cosmetics Ingredients Functions HAIR CONDITIONING
InChIKey OROIAVZITJBGSM-OJFKHTATSA-N
SMILES [n]2(c3[nH]c(n[c](c3nc2)=O)N)[C@@H]1O[C@@H]([C@H](C1)O)CO
CAS DataBase Reference 961-07-9(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII G9481N71RO
NIST Chemistry Reference Deoxyguanosine(961-07-9)
EPA Substance Registry System Guanosine, 2'-deoxy- (961-07-9)
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332
Precautionary statements  P261-P264-P270-P271-P280-P301+P312+P330-P302+P352+P312+P362+P364-P304+P340+P312-P501
Risk Statements  20/21/22
Safety Statements  24/25
WGK Germany  3
RTECS  MF8760000
F  10-23
TSCA  TSCA listed
HS Code  29349990
Storage Class 11 - Combustible Solids
NFPA 704
1
2 0

2'-Deoxyguanosine price More Price(50)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical D0052 2'-Deoxyguanosine Hydrate >98.0%(T) 961-07-9 1g $35 2026-04-30 Buy
TCI Chemical D0052 2'-Deoxyguanosine Hydrate >98.0%(T) 961-07-9 5g $105 2026-04-30 Buy
Cayman Chemical 9002864 2''-Deoxyguanosine 961-07-9 1g $35 2021-12-16 Buy
Cayman Chemical 9002864 2''-Deoxyguanosine 961-07-9 5g $88 2021-12-16 Buy
Biosynth ND06306 2'-Deoxyguanosine monohydrate 961-07-9 50g $627 2026-06-04 Buy
Product number Packaging Price Buy
D0052 1g $35 Buy
D0052 5g $105 Buy
9002864 1g $35 Buy
9002864 5g $88 Buy
ND06306 50g $627 Buy

2'-Deoxyguanosine Chemical Properties,Uses,Production

Chemical Properties

White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents.

Uses

2'-Deoxyguanosine (Deoxyguanosine; dG) is composed of the purine nucleoside guanine linked by its N9 nitrogen to the C1 carbon of deoxyribose. It is a purine nucleoside that upon sequential phosphoylation (kinases) forms dGTP which is used by DNA polymerases and reverse transcriptases to synthesis DNA(s). Deoxyguanosine is the most electron rich of the four canonical bases and includes many nucleophilic sites which are susceptible to oxidative damage. This makes deoxyguanosine and its oxidized derivatives useful reagents to study mechanisms of oxidative damage to nucleosides and nucleotides.

Definition

ChEBI: 2'-deoxyguanosine is a purine 2'-deoxyribonucleoside having guanine as the nucleobase. It has a role as a Saccharomyces cerevisiae metabolite, a human metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a purines 2'-deoxy-D-ribonucleoside and a purine 2'-deoxyribonucleoside. It is functionally related to a guanosine.

benefits

8-Hydroxy-2'-deoxyguanosine (8-OHdG) is the most commonly used marker of DNA oxidation for the diagnosis of oxidative DNA damage and bipolar disorder (BD), as well as for the prevention of plaque formation and for the inhibition of vascular smooth muscle cell activation through Rac1 inactivation.

Biological Functions

2‘-Deoxyguanosine (2’dGuo) is a purine nucleoside metabolite that has been shown to inhibit proliferation-dependent antigen-specific suppressor T cell (Ts) function in mouse and human systems. 2'dGuo also inhibits mitogen-induced T cell proliferation. Low concentrations (40 gM) of 2'dGuo enhanced phytohemagglutinin- and amantadine A-induced T-cell transformation, possibly due to the inhibition of T-cell function leading to the promotion of T-cell growth factor production. T-cell responses were inhibited only when the concentration of 2'dGuo was toxic to lymphocytes.[1]

IC 50

Human Endogenous Metabolite

Purification Methods

2'-Deoxyguanosine recrystallises from H2O as the monohydrate. [Brown &C5440 Lythgoe J Chem Soc 1990 1950, L

References

[1] A C HANGLOW; P M L. The effect of 2’deoxyguanosine on human lymphocyte responses. I. 2’deoxyguanosine enhances T lymphocyte responses.[J]. Clinical and experimental immunology, 1985, 59 3: 653-658.

2'-Deoxyguanosine Preparation Products And Raw materials

Raw materials

Preparation Products

OCHRATOXIN B DMT-dG(dmf) Phosphoramidite 8-Oxo-2'-deoxyguanosine 6-THIO-2'-DEOXYGUANOSINE 2'-DEOXY-4-DESMETHYLWYOSINE

2'-Deoxyguanosine Suppliers

Global( 524)Suppliers
Supplier Tel Email Country ProdList Advantage
Wuxi Helen Biotechnology Co., Ltd., 0510-85629785 18013409632 sales@reading-chemicals.com China 14072 58
Zhejiang Huida Biotech Co., LTD 0571-89903022 18679456698 zilong@hizyme.com China 8001 58
Xinxiang Meilin Biotechnology Co., LTD 15737397775; 15737397775 970007865@qq.com China 18 58
Hangzhou Huiyi Biotechnology Co., LTD 0571-89918262 13357170655 chenlingwei@hizyme.com China 105 58
Innobio Pharm Co.,Ltd 15600141006 sales@innovbiopharm.com China 117 58
Jiangsu Enzymatic Co.,Ltd. 0512-58587898 13812862084 AnnaXu@rexinbio.com China 52 58
Shanghai Boyle Chemical Co., Ltd. 021-50182298 021-50180596 sales@boylechem.com China 2202 55
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
INTATRADE GmbH +49 3493/605464 sales@intatrade.de Germany 3563 66
Supplier Advantage
Wuxi Helen Biotechnology Co., Ltd., 58
Zhejiang Huida Biotech Co., LTD 58
Xinxiang Meilin Biotechnology Co., LTD 58
Hangzhou Huiyi Biotechnology Co., LTD 58
Innobio Pharm Co.,Ltd 58
Jiangsu Enzymatic Co.,Ltd. 58
Shanghai Boyle Chemical Co., Ltd. 55
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
INTATRADE GmbH 66

Related articles

Related Questions

Ask a question
Q:What are the biological functions of 2'-Deoxyguanosine?STAR - Nov 4,2025
A:2'-Deoxyguanosine (2'-dG) is one of the nucleosides constituting DNA, functioning to influence gene regulation and being closely associated with purine metabolism and related diseases. Moreover, its modified form, 8-oxo-2'-deoxyguanosine (8-oxo-dG), is a well-recognised marker of oxidative stress and participates in processes including mutation, DNA repair, gene expression regulation, inflammatory responses, adaptive stress responses, apoptosis, and cellular transformation. 8-oxo-dG holds potential as a therapeutic agent for inflammatory, autoimmune, degenerative and neoplastic diseases, as well as traumatic and toxic injuries.[1] N. V. MARMIY  D. S E. 8-Oxo-2′-Deoxyguanosine: Oxidative Stress Control[J]. Russian Journal of Bioorganic Chemistry, 2025, 51 5: 1909-1916. DOI:10.1134/S1068162025602472.

View Lastest Price from 2'-Deoxyguanosine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2'-Deoxyguanosine monohydrate(2'-dG) pictures 2026-09-11 2'-Deoxyguanosine monohydrate(2'-dG)
961-07-9
 1kg 99%HPLC 1000T WeiTai BioPharmaceutical Co.,Ltd(Hangzhou)
2'-Deoxyguanosine monohydrate pictures 2026-09-11 2'-Deoxyguanosine monohydrate
961-07-9
 1KG 99% 10kg WUHAN FORTUNA CHEMICAL CO., LTD
2'-Deoxyguanosine pictures 2026-09-04 2'-Deoxyguanosine
961-07-9
 $10.00-99.00 1Kg 98% 1000kg Xinxiang Aurora Biotechnology Co.,Ltd.

2'-Deoxyguanosine Spectrum

2'-Deoxyguanosine monohydrate(961-07-9)MS2'-Deoxyguanosine monohydrate(961-07-9)1HNMR2'-Deoxyguanosine monohydrate(961-07-9)13CNMR2'-Deoxyguanosine monohydrate(961-07-9)IR12'-Deoxyguanosine monohydrate(961-07-9)IR2

961-07-9(2'-Deoxyguanosine)Related Search:

Deoxycholic acid MELIBIOSE Guanosine 5'-monophosphate disodium salt Guanosine Guanine
Acyclovir Chloral hydrate 5'-Guanylic acid Guanylic acid sodium salt 2'-DEOXYGUANOSINE5'-MONOPHOSPHATE,DISODIUM SALT(DGMP·2NA),2'-DEOXYGUANOSINE5'-MONOPHOSPHATE,DISODIUM SALT(DGMP·2NA)
N2-ISOBUTYRYL-5'-O-(4,4'-DIMETHOXYTRITYL)-2'-DEOXYGUANOSINE,N2-ISOBUTYRYL-5'-O-(4,4'-DIMETHOXYTRITYL)-2'-DEOXYGUANOSINE 2'-DEOXYGUANOSINE 5'-MONOPHOSPHATE DNA, single stranded, imm. on cellulose, from calf thymus* 2'-Deoxyguanosine-5'-triphosphoric acid, disodium 3'-deoxyguanosine monohydrate
hydrate hydrazine hydrate [5',5''-2H2]2'-deoxyguanosine monohydrate

1of4

DEOXYGUANOSINE-2' GUANINE DESOXYRIBOSIDE 2'-DEOXY-D-GUANOSINE A-2'-DEOXYGUANOSINE 9-(2'-DEOXY-BETA-D-RIBOFURANOSYL)GUANINE O6-Methyl-2&rsquo 2(acute)-Deoxyguanosine 2-amino-9-(4-hydroxy-5-methylol-tetrahydrofuran-2-yl)-3H-purin-6-one 2-amino-9-[4-hydroxy-5-(hydroxymethyl)-2-tetrahydrofuranyl]-3H-purin-6-one 2-amino-9-[4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-1,9-dihydro-6H-purin-6-one 2-amino-9-[4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-3H-purin-6-one 9H-Purin-6-ol, 2-amino-9-(2-deoxy-9-beta-D-ribofuranosyl)- deoxyephedrinearenol2’-deoxyguanosine Guanine, 9-(2-deoxy-beta-D-erythro-pentofuranosyl)- 2-DEOXYGUANOSINE extrapure 9-(2-Deoxy-β-D-ribofuranosyl)guanine, Guanine-2μ-deoxyriboside Norway saltpeter-15N2 2'-Deoxyguanosine ,98% 2'-Deoxyguanosine mo 2'-DEOXYGUANOSINE:H2O 2’-deoxy-guanosin Deoxyguanosine Monohydrat 2-aMino-9-((2R,4S,5R)-4-hydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one hydrate 2'-Deoxyguanosine Monohydrate SynonyMs 9-(2-Deoxy-beta-D-ribofuranosyl)guanine hydrate 2-AMino-9-((2R,4S,5R)-4-hydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)-3H-purin-6(9H)-one 2'-Deoxyguanosine Hydrate, 98.0%(T) -deoxy-N2-DMF-5&rsquo -O-DMT 8-Allyloxy-N2-(dimethylaminomethylidene)-2&rsquo -deoxy Guanosine-13C2,D, Major O6-(2-Hydroxy-1-methylethyl)-2&rsquo 7-Ethyl-2&rsquo N2-Methyl-2&rsquo O6-(2-Hydroxypropyl)-2&rsquo 8-Aza-7-deaza-2&rsquo 2'-Desoxyguanosin 7-Methyl-7-deaza-2&rsquo N1-Methyl-2&rsquo 8-Oxo-N2-isobutyryl-2&rsquo 8-(4-Amino-phenyl)-2&rsquo 9-(2-Deoxy-β-D-ribofuranosyl)guanine Guanine-2'-deoxyriboside 2'-DEOXYGUANOSINE CELL CULTURE TESTED DeoxyguanosineMonohydrate,Isolated 2'-Deoxyguanosine hydrate, 99+% 9-(2-deoxy-á-d-ribofuranosyl)guanine hydrate guanine-2'-deoxyriboside hydrate 2-amino-9-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one guaninedeoxyriboside Guanosine, 2'-deoxy- NSC 22837 9-(2-Deoxy-beta-D-ribofuranosyl)guanine hydrate Guanine-2'-deoxyriboside monohydrate 2-amino-9-[(4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one 9-(2-Deoxy--D-erythro-pentofuranosyl)guanine Monohydrate Deoxyguanosine Monohydrate Guanine Deoxyriboside Monohydrate 2'-Deoxyguanosine monohydrate (dG)