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8-OXO-2'-DEOXYGUANOSINE

8-OXO-2'-DEOXYGUANOSINE structure

CAS No.: 88847-89-6

Chemical Name:: 8-OXO-2'-DEOXYGUANOSINE

Synonyms: 8-Hydroxy-2'-deoxyguanosine;8-Hydroxy-2＇-deoxyguanosine;8-hydroxydeoxyguanosine;8-Hydroxy-dG;-deoxyguanosine;8-Hydroxy-2'-dG;8-Oxodeoxyguanosine;2-Amino-9-((2R,4S,5R);-3H-purine-6,8(7H,9H);2'-Deoxy-8-oxoguanosine

CBNumber:: CB6269667

Molecular Formula:: C10H13N5O5

Molecular Weight:: 283.24

MDL Number:: MFCD00210311

MOL File:: 88847-89-6.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 05:34:34

Product description	Number	Pack Size	Price
8-Hydroxy-2′-deoxyguanosine ≥98% (TLC)	H5653	1mg	$104
8-Hydroxy-2′-deoxyguanosine ≥98% (TLC)	H5653	5mg	$344
8-Hydroxy-2''-deoxyguanosine ≥98%	89320	1mg	$31
8-Hydroxy-2''-deoxyguanosine ≥98%	89320	5mg	$124
8-Hydroxy-2''-deoxyguanosine ≥98%	89320	10mg	$185
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8-OXO-2'-DEOXYGUANOSINE Properties

Melting point	217-220°C
Density	2.25±0.1 g/cm3(Predicted)
storage temp.	2-8°C
solubility	Soluble in DMSO (up to 10 mg/ml).
form	White to off-white solid.
pka	7.86±0.20(Predicted)
color	Off-white
Stability	Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
InChI	InChI=1S/C10H13N5O5/c11-9-13-7-6(8(18)14-9)12-10(19)15(7)5-1-3(17)4(2-16)20-5/h3-5,16-17H,1-2H2,(H,12,19)(H3,11,13,14,18)/t3-,4+,5+/m0/s1
InChIKey	HCAJQHYUCKICQH-VPENINKCSA-N
SMILES	OC[C@H]1O[C@@H](N2C3=C(C(NC(=N3)N)=O)NC2=O)C[C@@H]1O
FDA UNII	4RGB38T3IB
UNSPSC Code	12352200
NACRES	NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338
PPE	Eyeshields, Gloves, type N95 (US)
Safety Statements	24/25
WGK Germany	3
RTECS	MF8782675
HS Code	29349990
Storage Class	11 - Combustible Solids

8-OXO-2'-DEOXYGUANOSINE price More Price(58)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	H5653	8-Hydroxy-2′-deoxyguanosine ≥98% (TLC)	88847-89-6	1mg	$104	2026-04-30	Buy
Sigma-Aldrich	H5653	8-Hydroxy-2′-deoxyguanosine ≥98% (TLC)	88847-89-6	5mg	$344	2026-04-30	Buy
Cayman Chemical	89320	8-Hydroxy-2''-deoxyguanosine ≥98%	88847-89-6	1mg	$31	2026-04-30	Buy
Cayman Chemical	89320	8-Hydroxy-2''-deoxyguanosine ≥98%	88847-89-6	5mg	$124	2026-04-30	Buy
Cayman Chemical	89320	8-Hydroxy-2''-deoxyguanosine ≥98%	88847-89-6	10mg	$185	2026-04-30	Buy

Product number	Packaging	Price	Buy
H5653	1mg	$104	Buy
H5653	5mg	$344	Buy
89320	1mg	$31	Buy
89320	5mg	$124	Buy
89320	10mg	$185	Buy

8-OXO-2'-DEOXYGUANOSINE Chemical Properties,Uses,Production

Description

8-Oxo-2′-deoxyguanosine (88847-89-6) is a useful marker for DNA damage via a variety of oxidative processes.1It is a critical biomarker for oxidative stress and carcinogenesis.2,3

Chemical Properties

White Crystalline Solid

Uses

A marker compound indicative of DNA damage associated with mutagenesis and carcinogenesis. Can induce differentiation of Friend murine erythroleukemia cells in vitro.

Uses

8-Hydroxy-2′-deoxyguanosine has been used:

as a standard to analyse the oxidative DNA damage in the placenta of normal and abnormal pregnancies by electrochemical detection
as a standard for high performance liquid chromatography (HPLC) with electrochemical detection (ECD) measurement
as a standard for HPLC and as a urinary marker of oxidative stress in order to assess the potentialantioxidantactivity of green coffee bean extract (GCBE) in vivo
as a standard for LC/MS/MS analysis

Definition

ChEBI: Guanosine substituted at the purine 8-position by a hydroxy group. It is used as a biomarker of oxidative DNA damage.

Biochem/physiol Actions

A marker compound typically indicative of DNA damage associated with mutagenesis and carcinogenesis

References

[1] K B BECKMAN B N A. Oxidative decay of DNA.[J]. The Journal of Biological Chemistry, 1997, 272 32: 19633-19636. DOI:10.1074/jbc.272.32.19633
[2] ROBERTA ANDREOLI. Quantitative determination of urinary 8-oxo-7,8-dihydro-2’-deoxyguanosine, 8-oxo-7,8-dihydroguanine, 8-oxo-7,8-dihydroguanosine, and their non-oxidized forms: daily concentration profile in healthy volunteers.[J]. Biomarkers, 2010, 15 3: 221-231. DOI:10.3109/13547500903434501
[3] PAOLA MANINI . Biomarkers of nucleic acid oxidation, polymorphism in, and expression of, hOGG1 gene in styrene-exposed workers[J]. Toxicology letters, 2009, 190 1: Pages 41-47. DOI:10.1016/j.toxlet.2009.06.862

8-OXO-2'-DEOXYGUANOSINE synthesis

Synthesis of 8-OXO-2'-DEOXYGUANOSINE from 8-BROMO-2'-DEOXYGUANOSINE

8-OXO-2'-DEOXYGUANOSINE Preparation Products And Raw materials

Raw materials

4H-Imidazol-4-one, 2-amino-5-[(2-deoxy-β-D-erythro-pentofuranosyl)amino]- 8-Benzyloxy-2'-deoxy-D-guanosine 2'-Deoxyguanosine 8-BROMO-2'-DEOXYGUANOSINE

Preparation Products

8-OXO-2'-DEOXYGUANOSINE Suppliers

Global( 153)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Zhejiang ZETian Fine Chemicals Co. LTD	+8618957127338	stella@zetchem.com	China	2994	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10403	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Nanjing Baifuli Technology Co., Ltd.	+86-15335185688	sales@unisyn.cn	CHINA	332	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19936	58
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32466	58
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30225	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	20582	58
NewCan Biotech Limited	+86-571-86912261 19975279805	sales@newcanbio.com	China	9985	58
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd	+8618829768577	gao490372054@gamil.com	China	1249	58

Supplier	Advantage
Zhejiang ZETian Fine Chemicals Co. LTD	58
Shenzhen Nexconn Pharmatechs Ltd	58
Accela ChemBio Inc.	58
Nanjing Baifuli Technology Co., Ltd.	58
BOC Sciences	58
TargetMol Chemicals Inc.	58
Career Henan Chemica Co	58
Dideu Industries Group Limited	58
NewCan Biotech Limited	58
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd	58

View Lastest Price from 8-OXO-2'-DEOXYGUANOSINE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-04-22	8-Hydroxy-2'-deoxyguanosine 88847-89-6	$68.00-223.00		99.10%	10g	TargetMol Chemicals Inc.
	2025-04-04	8-OXO-2'-DEOXYGUANOSINE 88847-89-6		1kg	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.

8-Hydroxy-2'-deoxyguanosine
88847-89-6
$68.00-223.00
99.10%
TargetMol Chemicals Inc.

8-OXO-2'-DEOXYGUANOSINE
88847-89-6
98%
Henan Aochuang Chemical Co.,Ltd.

8-OXO-2'-DEOXYGUANOSINE Spectrum

8-OXO-2'-DEOXYGUANOSINE(88847-89-6)¹HNMR 8-OXO-2'-DEOXYGUANOSINE(88847-89-6)¹HNMR

88847-89-6(8-OXO-2'-DEOXYGUANOSINE)Related Search:

8-OXO-2'-DEOXYGUANOSINE Loxoribine 8-Benzyloxyguanosine Guanine Purine

7-propyl-8-oxoguanosine 8-HYDROXYGUANOSINE 5'-O-(4,4'-DIMETHOXYTRITYL)-N2-ISOBUTYRYL-8-OXO-2'-DEOXYGUANOSINE, 3'-[(2-CYANOETHYL)-(N,N-DIISOPROPYL)]PHOSPHORAMIDITE 8-ALLYLOXY-3'-O-[(DIISOPROPYLAMINO)(2-CYANOETHOXY)PHOSPHINO]-5'-O-(4,4'-DIMETHOXYTRITYL)-N2-[(DIMETHYLAMINO)METHYLIDINE]-2'-DEOXYGUANOSINE 8-ALLYLOXY-N2-ISOBUTYRYL-2'-DEOXYGUANOSINE

8-ALLYLOXY-2'-DEOXYGUANOSINE Tri-O-acetyl-8-(allyloxy)guanosine 5'-O-(DIMETHOXYTRITYL)-8-HYDROXY-N2-ISOBUTRYL-2'-DEOXYGUANOSINE 8-BENZYLOXY-N2-ISOBUTYRYL-2'-DEOXYGUANOSINE 8-HYDROXY-N2-ISOBUTRYL-2'-DEOXYGUANOSINE

8-ALLYLOXY-N2-(DMF)-2'-DEOXYGUANOSINE 8-Benzyloxy-2'-deoxy-D-guanosine 8-(Allyloxy)guanosine

1of4

2'-Deoxy-8-oxoguanosine 7,8-Dihydro-8-oxo-2'-deoxyguanosine 8-Oxo-7,8-dihydro-2'-deoxyguanosine 8-Oxo-7,8-dihydrodeoxyguanosine 2'-Deoxy-8-oxo-D-guanosine 8-Oxo-7,8-dihydro-2μ-deoxyguanosine, 8-Oxo-dG 2'-Deoxy-8-hydroxyguanosine 8-Oxodeoxyguanosine 2-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3,7-dihydropurine-6,8-dione 2-amino-9-[(2R,4S,5R)-4-hydroxy-5-methylol-tetrahydrofuran-2-yl]-3,7-dihydropurine-6,8-quinone 2-azanyl-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3,7-dihydropurine-6,8-dione 8-Hydroxy-2′-deoxyguanosine,8-Oxo-7,8-dihydro-2′-deoxyguanosine, 8-Oxo-dG 8-Hydroxy-2'-deoxyguanosineDiscontinued See O850250 2-AMino-9-((2R,4S,5R)-4-hydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)-3H-purine-6,8(7H,9H)-dione Guanosine,2'-deoxy-7,8-dihydro-8-oxo- 7,8-dihydro-2’-deoxy-8-oxo-guanosin 2-Amino-9-((2R,4S,5R) -3H-purine-6,8(7H,9H) 8-Oxo-2'-deoxyguanosine (8-Oxo-dG) 7,8-dihydro-2’-deoxy-8-oxoguanosine 8-hydroxydeoxyguanosine 8-oxo-7-hydrodeoxyguanosine 8-Hydroxy-desoxyguanosine 8-OXO-2'-DEOXYGUANOSINE USP/EP/BP -deoxyguanosine 8-Hydroxy-2'-dG 8-Hydroxy-dG 8-HYDROXY-2'-DEOXYGUANOSINE UNLABELED 25 UG/ML IN WATER Inhibitor,8Hydroxy2'deoxyguanosine,inhibit,Endogenous Metabolite,8 Hydroxy 2' deoxyguanosine 2-amino-8-hydroxy-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one 8-oxo-2'-deoxyGuanosine 2'-Deoxy-7,8-dihydro-8-oxoguanosine 2-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,7,8,9-tetrahydro-3H-purine-6,8-dione 2’-Deoxy-8-oxoguanosine 8-Hydroxy-2'-deoxyguanosine (8-OHdG） *Carisoprodol Impurity 4 (Carisoprodol EP Impurity D)(Meprobamate) Rabbit Anti-8-OHdG (DNA/RNA Damage) antibody 8-Hydroxy-2''-deoxyguanosine, Oxidative stress biomarker 8-Hydroxy-2''-deoxyguanosine 8-Hydroxy-2''-deoxyguanosine, 10 mM in DMSO Mouse 8-Hydroxy-desoxyguanosine elisa kit 8-Oxo-2’-deoxyguanosine 8-Hydroxy-2'-deoxyguanosine - [H70903] 8-Hydroxy-2'-deoxyguanosine 8-Hydroxy-2＇-deoxyguanosine 88847-89-6 8847-89-6 Bases & Related Reagents Labeling and Diagnostics Reagents Nucleotides Heterocycles