3-Iodobenzaldehyde[4-(diphenylamino)-6-(4-morpholinyl)-1,3,5-triazin-2-yl]hydrazone
- CAS No.
- 351986-85-1
- Chemical Name:
- 3-Iodobenzaldehyde[4-(diphenylamino)-6-(4-morpholinyl)-1,3,5-triazin-2-yl]hydrazone
- Synonyms
- Vacuolin-1;Vacuolin-1 ,S6912;Vacuolin-1, 10 mM in DMSO;Vacuolin-1 - CAS 351986-85-1 - Calbiochem;Diethylcarbamazine Impurity 1(Diethylcarbamazine EP Impurity A);4-(2-(3-Iodobenzylidene)hydrazinyl)-6-morpholino-N,N-diphenyl-1,3,5-triazin-2-amine;3-Iodobenzaldehyde[4-(diphenylamino)-6-(4-morpholinyl)-1,3,5-triazin-2-yl]hydrazone;(E)-4-(2-(3-iodobenzylidene)hydrazinyl)-6-Morpholino-N,N-diphenyl-1,3,5-triazin-2-aMine;Benzaldehyde, 3-iodo-, 2-[4-(diphenylamino)-6-(4-morpholinyl)-1,3,5-triazin-2-yl]hydrazone;4-[(2E)-2-(3-iodobenzylidene)hydrazinyl]-6-(morpholin-4-yl)-N,N-diphenyl-1,3,5-triazin-2-amine
- CBNumber:
- CB32096419
- Molecular Formula:
- C26H24IN7O
- Molecular Weight:
- 577.42
- MDL Number:
- MFCD00321410
- MOL File:
- 351986-85-1.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Vacuolin-1 - CAS 351986-85-1 - Calbiochem | 673000 | 10mg | $205 |
| Vacuolin-1 ≥95% | 20425 | 1mg | $37 |
| Vacuolin-1 ≥95% | 20425 | 5mg | $98 |
| Vacuolin-1 ≥95% | 20425 | 10mg | $161 |
| Vacuolin-1 | 20425 | 25mg | $353 |
| Boiling point | 719.7±70.0 °C(Predicted) |
|---|---|
| Density | 1.53±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility |
DMSO:18.33(Max Conc. mg/mL);31.74(Max Conc. mM) DMSO:PBS (pH 7.2) (1:7):0.12(Max Conc. mg/mL);0.21(Max Conc. mM) DMF:3.0(Max Conc. mg/mL);5.2(Max Conc. mM) |
| form | White solid |
| pka | 10.74±0.10(Predicted) |
| color | White to off-white |
| Appearance | white powder |
| InChIKey | JMEJTSRAQUFNOP-TURZUDJPSA-N |
| SMILES | Ic1cc(ccc1)\C=N\Nc2nc(nc(n2)N(c5ccccc5)c4ccccc4)N3CCOCC3 |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22 | |||||||||
| WGK Germany | WGK 3 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
3-Iodobenzaldehyde[4-(diphenylamino)-6-(4-morpholinyl)-1,3,5-triazin-2-yl]hydrazone price More Price(17)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 673000 | Vacuolin-1 - CAS 351986-85-1 - Calbiochem | 351986-85-1 | 10mg | $205 | 2026-03-19 | Buy |
| Cayman Chemical | 20425 | Vacuolin-1 ≥95% | 351986-85-1 | 1mg | $37 | 2024-03-01 | Buy |
| Cayman Chemical | 20425 | Vacuolin-1 ≥95% | 351986-85-1 | 5mg | $98 | 2024-03-01 | Buy |
| Cayman Chemical | 20425 | Vacuolin-1 ≥95% | 351986-85-1 | 10mg | $161 | 2024-03-01 | Buy |
| Cayman Chemical | 20425 | Vacuolin-1 | 351986-85-1 | 25mg | $353 | 2024-03-01 | Buy |
3-Iodobenzaldehyde[4-(diphenylamino)-6-(4-morpholinyl)-1,3,5-triazin-2-yl]hydrazone Chemical Properties,Uses,Production
Description
Vacuolin-1 is a triazine-based small chemical, a specific inhibitor of Ca2+–dependent lysosomal exocytosis. The inhibitor penetrates the cell, blocking the fusion of lysosomes with the plasma membrane. Vacuolin-1 does not affect other membrane-bound organelles and endocytic or secretory traffic. The inhibitor is widely used in studies on the release of lysosomal content and the modulation of autophagy.
Uses
Vacuolin-1 is a cell-permeable triazine that inhibits Ca2+-dependent fusion of lysosomes to the cell membrane inhibiting release of lysosomal content.
Biological Activity
Cell permeable: yes', 'Primary Target
Ca2+-dependent fusion of lysosomes with the plasma membrane', 'Product does not compete with ATP.', 'Reversible: no
3-Iodobenzaldehyde[4-(diphenylamino)-6-(4-morpholinyl)-1,3,5-triazin-2-yl]hydrazone Preparation Products And Raw materials
Raw materials
Preparation Products
3-Iodobenzaldehyde[4-(diphenylamino)-6-(4-morpholinyl)-1,3,5-triazin-2-yl]hydrazone Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32467 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8615965530500 | nickzhang@hangyubiotech.com | China | 8614 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 43333 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| Wuhan Jingkang en Biomedical Technology Co., Ltd | +8613720134139 | orders@jknbiochem.com | China | 5221 | 58 |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11780 | 60 |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12984 | 57 | |
| ShangHai Caerulum Pharma Discovery Co., Ltd. | 18149758185 18149758185 | sales-cpd@caerulumpharma.com | China | 3505 | 58 |
| Bide Pharmatech Ltd. | 400-400-164-7117 18317119277 | product02@bidepharm.com | China | 39999 | 60 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696,15000506266 15000506266 | China | 4817 | 55 |
View Lastest Price from 3-Iodobenzaldehyde[4-(diphenylamino)-6-(4-morpholinyl)-1,3,5-triazin-2-yl]hydrazone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-04-22 | Vacuolin-1
351986-85-1
|
US $31.00-113.00 / mg | 99.45% | 10g | TargetMol Chemicals Inc. |
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- Vacuolin-1
351986-85-1
- US $31.00-113.00 / mg
- 99.45%
- TargetMol Chemicals Inc.





