1-BROMO-2-NAPHTHALDEHYDE
- CAS No.
- 3378-82-3
- Chemical Name:
- 1-BROMO-2-NAPHTHALDEHYDE
- Synonyms
- 1-Bromo-2-naphthal;1-broMo-2-phthaldehyde;1-BROMO-2-NAPHTHALDEHYDE;1-Bromo-2-naphthaldehyde >1-BROMO-2-NAPHTHALDEHYDE 96+%;1-Bromo-2-naphthalenecarbaldehyde;1-BROMONAPHTHALENE-2-CARBALDEHYDE;1-Bromo-2-naphthalenecarboxaldehyde;1-bromo-2-naphthaldehyde crystalline;2-Naphthalenecarboxaldehyde, 1-bromo-
- CBNumber:
- CB3225530
- Molecular Formula:
- C11H7BrO
- Molecular Weight:
- 235.08
- MDL Number:
- MFCD00046368
- MOL File:
- 3378-82-3.mol
- MSDS File:
- SDS
| Melting point | 118°C |
|---|---|
| Boiling point | 347℃ |
| Density | 1.552 |
| Flash point | 120℃ |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | soluble in Methanol |
| form | crystals |
| Appearance | Off-white to yellow Solid |
| BRN | 2613639 |
| InChI | InChI=1S/C11H7BrO/c12-11-9(7-13)6-5-8-3-1-2-4-10(8)11/h1-7H |
| InChIKey | CYGUXEZVBLMVRV-UHFFFAOYSA-N |
| SMILES | C1(Br)=C2C(C=CC=C2)=CC=C1C=O |
| CAS DataBase Reference | 3378-82-3(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29130000 | |||||||||
| NFPA 704 |
|
1-BROMO-2-NAPHTHALDEHYDE price More Price(22)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 779636 | 1-Bromo-2-naphthaldehyde ≥96.0% (HPLC) | 3378-82-3 | 1g | $148 | 2025-07-31 | Buy |
| TCI Chemical | B1647 | 1-Bromo-2-naphthaldehyde >96.0%(GC) | 3378-82-3 | 1g | $88 | 2025-07-31 | Buy |
| TCI Chemical | B1647 | 1-Bromo-2-naphthaldehyde >96.0%(GC) | 3378-82-3 | 5g | $260 | 2025-07-31 | Buy |
| TCI Chemical | B1647 | 1-Bromo-2-naphthaldehyde >96.0%(GC) | 3378-82-3 | 25g | $779 | 2025-07-31 | Buy |
| TRC | B688455 | 1-Bromo-2-naphthaldehyde | 3378-82-3 | 25g | $1045 | 2021-12-16 | Buy |
1-BROMO-2-NAPHTHALDEHYDE Chemical Properties,Uses,Production
Chemical Properties
Light yellow solid
Uses
1-Bromo-2-naphthaldehyde is used as a reagent in the synthesis of Hoveyda-Grubbs type metathesis catalysts which are used in cross olefin metathesis. 1-Bromo-2-naphthaldehyde is also used in the preparation of novel (-)-cercosporamide derivatives as potent selective PPARγ modulators.
Synthesis Reference(s)
The Journal of Organic Chemistry, 46, p. 4617, 1981 DOI: 10.1021/jo00335a076
Synthesis
37763-43-2
3378-82-3
General procedure for the synthesis of 1-bromo-2-naphthalene formaldehyde from 1-bromo-2-(bromomethyl)naphthalene: In a 2L reactor, 4-methylmorpholine N-oxide (61.4 g, 524 mmol), molecular sieves (200 g) and acetonitrile (1.2 L) were added and stirred for 30 min at 0 °C under nitrogen protection. Subsequently, 1-bromo-2-(bromomethyl)naphthalene (78 g, 262 mmol) was added and stirring was continued for 6 hours at room temperature. After completion of the reaction, the reaction mixture was filtered and the filtrate was washed with dichloromethane. The filtrate was concentrated and purified by column chromatography to afford 1-bromo-2-naphthaldehyde (45 g) in 73% yield.
References
[1] European Journal of Organic Chemistry, 2012, # 31, p. 6155 - 6164,10
[2] European Journal of Organic Chemistry, 2012, # 31, p. 6155 - 6164
[3] Tetrahedron Letters, 1994, vol. 35, # 48, p. 8985 - 8988
[4] Patent: US2018/72753, 2018, A1. Location in patent: Paragraph 0163-0164
[5] Journal of the Chemical Society, Perkin Transactions 1, 2000, # 9, p. 1363 - 1378
1-BROMO-2-NAPHTHALDEHYDE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 12930 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29855 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29800 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569262 +86-15003564040 | 1087@dideu.com | China | 3947 | 58 |
| Richest Group Ltd | 18017061086 | oled@richest-group.com | CHINA | 5600 | 58 |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 12233 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Shanghai UCHEM Inc. | +862156762820 +86-13564624040 | sales@myuchem.com | China | 8357 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
View Lastest Price from 1-BROMO-2-NAPHTHALDEHYDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-01-03 | 1-Bromo-2-naphthaldehyde
3378-82-3
|
US $0.00-0.00 / KG | 10mg | 99%HPLC | 2000tons | Shaanxi Dideu Medichem Co. Ltd | |
 |
2019-07-06 | 1-BROMO-2-NAPHTHALDEHYDE
3378-82-3
|
US $2.00 / KG | 1KG | 99% | customise | Career Henan Chemical Co |
-
- 1-Bromo-2-naphthaldehyde
3378-82-3
- US $0.00-0.00 / KG
- 99%HPLC
- Shaanxi Dideu Medichem Co. Ltd
-
- 1-BROMO-2-NAPHTHALDEHYDE
3378-82-3
- US $2.00 / KG
- 99%
- Career Henan Chemical Co
