ChemicalBook >> CAS DataBase List >>Unii-I18S89p20r
Unii-I18S89p20r
- CAS No.
- 934246-14-7
- Chemical Name:
- Unii-I18S89p20r
- Synonyms
- Unii-I18S89p20r;Degarelix (acetate H2O);Degarelix Acetate Hydrate;D-Alaninamide, N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-4-((((4S)-hexahydro-2,6- dioxo-4-pyrimidinyl)carbonyl)amino)-L-phenylalanyl-4-((aminocarbonyl)amino)-D-phenylalanyl-L-leucyl-N6-(1-methylethyl)-L-lysyl-L-prolyl-, acetate, hydrate (1::)
- CBNumber:
- CB32497795
- Molecular Formula:
- C84H107ClN18O18
- Molecular Weight:
- 1692.34
- MDL Number:
- MOL File:
- 934246-14-7.mol
- TDS File:
- TDS
Last updated:2026-08-05 09:01:00
| Melting point | >230°C (dec.) |
|---|---|
| storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| solubility | DMSO (Slightly) |
| form | Solid |
| color | White to Off-White |
| FDA UNII | I18S89P20R |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS08,GHS07 |
|---|---|
| Signal word | Danger |
| Hazard statements | H335-H302-H360 |
| Precautionary statements | P264-P270-P301+P312-P330-P501 |
Unii-I18S89p20r price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | TRC-D495466-2.5MG | Degarelix Acetate Hydrate | 934246-14-7 | 2.5mg | $376 | 2026-06-03 | Buy |
| TRC | TRC-D495466-1MG | Degarelix Acetate Hydrate | 934246-14-7 | 1mg | $182 | 2026-06-03 | Buy |
| Biosynth | JMB24614 | Degarelix acetate hydrate | 934246-14-7 | 10mg | $275 | 2026-06-04 | Buy |
| Biosynth | JMB24614 | Degarelix acetate hydrate | 934246-14-7 | 25mg | $447 | 2026-06-04 | Buy |
| Biosynth | JMB24614 | Degarelix acetate hydrate | 934246-14-7 | 50mg | $687.5 | 2026-06-04 | Buy |
Unii-I18S89p20r Chemical Properties,Uses,Production
Uses
The Acetate salt of Degarelix (D495465) which is a competitive and reversible gonadotropin-releasing hormone receptor (GnRHR) antagonist.
in vivo
Degarelix (0-10 μg/kg; s.c.; once) decreases plasma LH levels and plasma testosterone levels in a dose-dependent manner in castrated rats[3].
Degarelix is stable when incubated in microsomes and cryopreserved hepatocytes from animal liver tissue. In rat and dog, most of the degarelix dose is eliminated within 48 h via urine and feces in equal amounts (40–50% in each matrix), whereas in monkey the major route of excretion is fecal (50%) and renal (22%)[4].
| Animal Model: | Male Sprague-Dawley rats, castrated[3] |
| Dosage: | 0.3, 1, 3 and 10 μg/kg or 12.5, 50, and 200 μg/kg |
| Administration: | Subcutaneous injection, once |
| Result: | Produced a dose-dependent and reversible decrease in plasma LH levels with a minimal effective dose of 3 μg/kg. For the 50 μg/kg and 200 μg/kg doses, t1/2 of absorption values were 4 min and 30 min, Tmax values were 1 h and 5 h, and apparent plasma disappearance t1/2 values were 12 h and 67 h, respectively. Produced a dose-dependent decrease in plasma testosterone levels with a minimal effective dose of 1 μg/kg. |
Unii-I18S89p20r Preparation Products And Raw materials
Raw materials
Preparation Products
Unii-I18S89p20r Suppliers
Global( 7)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou Peptidego Biotech Co.,Ltd. | 0571-87213919 15967184799 | Eric@peptidego.com | China | 7872 | 58 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 | sales@sarms4muscle.com | China | 10378 | 58 |
| LGC Science (Shanghai) Ltd. | 17717235263 17717235263 | offer.de@lgcgroup.com | China | 38135 | 58 |
| Shenzhen Shengda Pharma Limited | 755-85269922 | sales@shengdapharm.com | CHINA | 310 | 58 |
| Supplier | Advantage |
|---|---|
| Hangzhou Peptidego Biotech Co.,Ltd. | 58 |
| BOC Sciences | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | 58 |
| LGC Science (Shanghai) Ltd. | 58 |
| Shenzhen Shengda Pharma Limited | 58 |
934246-14-7(Unii-I18S89p20r)Related Search:
Unii-I18S89p20r
Degarelix (acetate H2O)
D-Alaninamide, N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-4-((((4S)-hexahydro-2,6- dioxo-4-pyrimidinyl)carbonyl)amino)-L-phenylalanyl-4-((aminocarbonyl)amino)-D-phenylalanyl-L-leucyl-N6-(1-methylethyl)-L-lysyl-L-prolyl-, acetate, hydrate (1::)
Degarelix Acetate Hydrate
934246-14-7
