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(±)5,6-DHET lactone

CAS No.
213126-92-2
Chemical Name:
(±)5,6-DHET lactone
Synonyms
(±)5,6-DHET lactone;(±)5(6)-DiHET lactone;(+/-)5,6-DHET lactone;(±)5(6)-DiHET lactone;(±)5,6-DHET lactone, CAS 213126-92-2;(6S)-6-[(1R,3Z,6Z,9Z)-1-hydroxypentadeca-3,6,9-trienyl]oxan-2-one;2H-Pyran-2-one, tetrahydro-6-[(3Z,6Z,9Z)-1-hydroxy-3,6,9-pentadecatrien-1-yl]-
CBNumber:
CB32589801
Molecular Formula:
C20H32O3
Molecular Weight:
320.47
MDL Number:
MOL File:
213126-92-2.mol
MSDS File:
SDS
Last updated:2026-05-28 01:08:06

(±)5,6-DHET lactone Properties

Boiling point 483.4±40.0 °C(Predicted)
Density 0.993±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS pH 7.2: 1 mg/ml
pka 13.89±0.20(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)Health Hazard (GHS08)
GHS02,GHS08
Signal word  Danger
Hazard statements  H225-H350
Precautionary statements  P201-P202-P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P308+P313-P370+P378-P403+P235-P405-P501
NFPA 704
3
0 0

(±)5,6-DHET lactone price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 51212 (±)5(6)-DiHET lactone ≥98% 213126-92-2 25μg $102 2026-04-30 Buy
Cayman Chemical 51212 (±)5(6)-DiHET lactone ≥98% 213126-92-2 50μg $192 2026-04-30 Buy
Cayman Chemical 51212 (±)5(6)-DiHET lactone ≥98% 213126-92-2 100μg $357 2026-04-30 Buy
Cayman Chemical 51212 (±)5(6)-DiHET lactone ≥98% 213126-92-2 250μg $791 2026-04-30 Buy
Product number Packaging Price Buy
51212 25μg $102 Buy
51212 50μg $192 Buy
51212 100μg $357 Buy
51212 250μg $791 Buy

(±)5,6-DHET lactone Chemical Properties, Uses, Production

Uses

5,6-DiHET lactone ((±)5,6-DiHETrE lactone) is a lactonized form of 5,6-EET and 5,6-DiHET. In solution, 5(6)-EET degrades into 5(6)-DiHET and 5(6)-δ-lactone, which can be converted to 5(6)-DiHET and quantified by GC-MS.1 5,6-DiHET potently induces vasodilation of isolated canine coronary arterioles, with 41 and 100% inhibition occurring at 0.01 and 100 pM, respectively. It also induces vasodilation in isolated human microvessels and increases intracellular calcium levels in a dose-dependent manner, an effect that can be blocked by the nitric oxide scavenger L-NAME.

Definition

ChEBI: 5,6-Dihydroxy-8Z,11Z,14Z-eicosatrienoic acid, 1,5-lactone is a long-chain fatty alcohol.

References

[1] Oltman, et al. Epoxyeicosatrienoic acids and dihydroxyeicosatrienoic acids are potent vasodilators in the canine coronary microcirculation. Circ. Res. 83(9), 932-939 (1998).

(±)5,6-DHET lactone Preparation Products And Raw materials

Raw materials

Preparation Products

(±)5,6-DHET lactone Suppliers

Global Suppliers ( 14)
Supplier Tel Email Country ProdList Advantage
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 400-920-5774 sales@glpbio.cn China 6705 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8137 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58
SHANGHAI ZZBIO CO., LTD. 18019219489 18901678489 tech@zzbioco.com China 12062 58
DAYANG CHEM (HANGZHOU) CO.,LTD +86-88938639 +86-17705817739 info@dycnchem.com China 53736 58

View Latest Price from (±)5,6-DHET lactone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(±)5(6)-DiHET lactone pictures 2025-12-22 (±)5(6)-DiHET lactone
213126-92-2
10g TargetMol Chemicals Inc.
(±)5,6-DHET lactone (±)5(6)-DiHET lactone (6S)-6-[(1R,3Z,6Z,9Z)-1-hydroxypentadeca-3,6,9-trienyl]oxan-2-one 2H-Pyran-2-one, tetrahydro-6-[(3Z,6Z,9Z)-1-hydroxy-3,6,9-pentadecatrien-1-yl]- (±)5(6)-DiHET lactone (+/-)5,6-DHET lactone (±)5,6-DHET lactone, CAS 213126-92-2 213126-92-2