OL-135
- CAS No.
- 681135-77-3
- Chemical Name:
- OL-135
- Synonyms
- OL-135;1-Oxo-1-[5-(2-pyridyl)oxazol-2-yl]-7-phenylheptane;7-Phenyl-1-[5-(2-pyridinyl)-2-oxazolyl]-1-heptanone;1-Heptanone, 7-phenyl-1-[5-(2-pyridinyl)-2-oxazolyl]-;7-phenyl-1-(5-pyridin-2-yl-1,3-oxazol-2-yl)heptan-1-one
- CBNumber:
- CB32628209
- Molecular Formula:
- C21H22N2O2
- Molecular Weight:
- 334.41
- MDL Number:
- MOL File:
- 681135-77-3.mol
- MSDS File:
- SDS
| storage temp. | 2-8°C |
|---|---|
| solubility | DMSO: soluble5mg/mL, clear (warmed) |
| form | powder |
| color | white to beige |
| InChI | 1S/C21H22N2O2/c24-19(14-7-2-1-4-10-17-11-5-3-6-12-17)21-23-16-20(25-21)18-13-8-9-15-22-18/h3,5-6,8-9,11-13,15-16H,1-2,4,7,10,14H2 |
| InChIKey | ILOIOIGZFHGSMS-UHFFFAOYSA-N |
| SMILES | n1c([o]c(c1)c3ncccc3)C(=O)CCCCCCc2ccccc2 |
| FDA UNII | NC2J8K4ARH |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
OL-135 price More Price(10)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML0933 | OL-135 ≥98% (HPLC) | 681135-77-3 | 25mg | $512 | 2026-04-30 | Buy |
| Sigma-Aldrich | SML0933 | OL-135 ≥98% (HPLC) | 681135-77-3 | 5mg | $107 | 2022-05-15 | Buy |
| ChemScene | CS-0002863 | OL-135 98% | 681135-77-3 | 5mg | $355 | 2026-06-04 | Buy |
| ChemScene | CS-0002863 | OL-135 98% | 681135-77-3 | 10mg | $570 | 2026-06-04 | Buy |
| ChemScene | CS-0002863 | OL-135 98% | 681135-77-3 | 25mg | $1140 | 2026-06-04 | Buy |
OL-135 Chemical Properties, Uses, Production
Uses
OL-135 is a CNS penetrant, selective, and reversible of FAAH inhibitor. OL-135 exhibits analgesic activity[1].
Biological Activity
OL-135 is a CNS penetrant, highly potent and selective reversible inhibitor of FAAH devoid of CB1, CB2 and μ and δ opioid receptors activities th at increases the analgesic and hypothermic activity of anandamide.
References
[1] Duncan KK, et al. α-Ketoheterocycle inhibitors of fatty acid amide hydrolase: exploration of conformational constraints in the acyl side chain. Bioorg Med Chem. 2014;22(9):2763-2770. DOI:10.1016/j.bmc.2014.03.013
OL-135 Preparation Products And Raw materials
Raw materials
Preparation Products
OL-135 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 025-85560043 13675144456 | sean.lv@synzest.com | China | 11432 | 58 |
| Beijing Biocreative Technology Co., Ltd. | 15522676233 | 3007606172@qq.com | China | 1246 | 58 |
| Nantong QuanYi Biotechnology Co., Ltd | 0513-66337626 18051384581 | sales@chemhifuture.com | China | 5985 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| TargetMol Chemicals Inc. | 13564774135 | marketing@targetmol.com | United States | 19950 | 58 |
