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1-Boc-4-Propylaminopiperidine

CAS No.
301225-58-1
Chemical Name:
1-Boc-4-Propylaminopiperidine
Synonyms
4-Propylamino-1-Boc;1-BOC-4-PROPYLAMINOPIPERIDINE;N-Boc-4-propylaminopiperidine;4-PROPYLAMINO-1-BOC-PIPERIDINE;tert-butyl 4-(propylamino)piperidine-1-carboxylate;4-(Prop-1-ylamino)piperidine, N1-BOC protected 97%;4-PROPYLAMINO-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;1-Piperidinecarboxylic acid, 4-(propylamino)-, 1,1-dimethylethyl ester
CBNumber:
CB3270611
Molecular Formula:
C13H26N2O2
Molecular Weight:
242.36
MDL Number:
MFCD07367771
MOL File:
301225-58-1.mol
MSDS File:
SDS
Last updated:2026-05-28 01:11:18

1-Boc-4-Propylaminopiperidine Properties

Boiling point 322.6±35.0 °C(Predicted)
Density 0.99±0.1 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
pka 10.25±0.20(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338
HS Code  2933399990

1-Boc-4-Propylaminopiperidine price More Price(28)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Matrix Scientific 223798 tert-Butyl 4-(propylamino)piperidine-1-carboxylate 301225-58-1 5.00g $290 2026-05-18 Buy
Matrix Scientific 223798 tert-Butyl 4-(propylamino)piperidine-1-carboxylate 301225-58-1 10.00g $521 2026-05-18 Buy
Synthonix B57281 tert-Butyl 4-(propylamino)piperidine-1-carboxylate 97% 301225-58-1 1g $530 2026-05-06 Buy
Synthonix B57281 tert-Butyl 4-(propylamino)piperidine-1-carboxylate 97% 301225-58-1 5g $2650 2026-05-06 Buy
Synthonix B57281 tert-Butyl 4-(propylamino)piperidine-1-carboxylate 97% 301225-58-1 10g $5300 2026-05-06 Buy
Product number Packaging Price Buy
223798 5.00g $290 Buy
223798 10.00g $521 Buy
B57281 1g $530 Buy
B57281 5g $2650 Buy
B57281 10g $5300 Buy

1-Boc-4-Propylaminopiperidine Chemical Properties, Uses, Production

Synthesis

Propylamine

107-10-8

N-(tert-Butoxycarbonyl)-4-piperidone

79099-07-3

1-Boc-4-Propylaminopiperidine

301225-58-1

Step A: N-tert-butoxycarbonyl-4-piperidone (5 g, 25 mmol), n-propylamine (3.69 mL, 45 mmol), acetic acid (1.43 mL, 25 mmol), and sodium triacetoxyborohydride (7.95 g, 37.5 mmol) were dissolved in dichloromethane (100 mL) and the reaction was stirred for 16 h at room temperature. After completion of the reaction, the reaction mixture was washed with deionized water (50 mL) and then with saturated sodium bicarbonate solution. The aqueous phase was back-extracted with dichloromethane (20 mL), and all organic phases were combined, dried with anhydrous magnesium sulfate, and concentrated under reduced pressure to give 1-N-Boc-4-propylaminopiperidine 6 g in 95% yield.

References

[1] Bioorganic and Medicinal Chemistry Letters, 2001, vol. 11, # 18, p. 2475 - 2479
[2] Patent: US6498161, 2002, B1
[3] Bioorganic and Medicinal Chemistry Letters, 2008, vol. 18, # 1, p. 336 - 343

1-Boc-4-Propylaminopiperidine Preparation Products And Raw materials

Global Suppliers ( 47)
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Shanghai Sunway Pharmaceutical Technology Co., Ltd 13761987713 hxzheng@sunwaypharm.cn China 8663 57
Chengdu Forest Science and Technology Development Co., Ltd. 18030648795 18030648795 sales@cdforestchem.com China 2000 58
9ding chemical ( Shanghai) Limited 4009209199 sales@9dingchem.com China 18201 56
Tianjing Geneston Bio-tech Co.,Ltd. 022-60131465 18920720807 zishan_1986@163.com China 744 58
JW & Y Pharmlab Co., Ltd. 021-64340559 xinyu_shi@jwypharmlab.com.cn China 11999 58
Chengdu J&B Technology Co., Ltd. 028-61186694 15608078506 609128801@qq.com China 853 55
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Yantai ShengKailun Chemical Technology Co., Ltd. 13356901049 3119594100@qq.com China 7964 55
Amatek Scientific Co. Ltd. 0512-56316828 400-867-5858;400-867-5858 info@amateksci.com China 28760 58

View Latest Price from 1-Boc-4-Propylaminopiperidine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-Boc-4-Propylaminopiperidine pictures 2020-01-13 1-Boc-4-Propylaminopiperidine
301225-58-1
$1.00 1KG 98% 10 tons Career Henan Chemical Co
4-PROPYLAMINO-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 4-PROPYLAMINO-1-BOC-PIPERIDINE 4-Propylamino-1-Boc 1-BOC-4-PROPYLAMINOPIPERIDINE tert-butyl 4-(propylamino)piperidine-1-carboxylate N-Boc-4-propylaminopiperidine 4-(Prop-1-ylamino)piperidine, N1-BOC protected 97% 1-Piperidinecarboxylic acid, 4-(propylamino)-, 1,1-dimethylethyl ester 301225-58-1