tert-Butyl acetoacetate
- CAS No.
- 1694-31-1
- Chemical Name:
- tert-Butyl acetoacetate
- Synonyms
- TBAA;tert-Butyl 3-oxobutanoate;ACTB;Beta-actin;T-BUTYL ACETOACETATE;bact;actba;bactzf;bactin1;CEDI-002
- CBNumber:
- CB0441030
- Molecular Formula:
- C8H14O3
- Molecular Weight:
- 158.2
- MDL Number:
- MFCD00008811
- MOL File:
- 1694-31-1.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Anti-Actin-pan, C-Terminal antibody produced in rabbit affinity isolated antibody | SAB4502632 | 100 μg | $522 |
| MONOCLONAL ANTI-BETA-ACTIN antibody produced in mouse clone 137CT26.1.1, IgG fraction of antiserum, buffered aqueous solution | SAB1305554 | 400 μL | $496 |
| MONOCLONAL ANTI-BETA-ACTIN antibody produced in mouse clone 8H10D10, IgG fraction of antiserum, buffered aqueous solution | SAB1305546 | 400 μL | $496 |
| tert-Butyl acetoacetate reagent grade, 98% | 537594 | 1l | $258 |
| tert-Butyl acetoacetate reagent grade, 98% | 537594 | 4l | $402 |
| More product size | |||
| Melting point | -38 °C (lit.) |
|---|---|
| Boiling point | 71-72 °C/11 mmHg (lit.) |
| Density | 0.954 g/mL at 25 °C (lit.) |
| vapor pressure | 79.32Pa at 25℃ |
| refractive index |
n |
| Flash point | 150 °F |
| storage temp. | -20°C |
| solubility | 9g/l |
| pka | 10.71±0.46(Predicted) |
| form | Liquid |
| color | clear |
| PH | 5.7 (9g/l, H2O, 20℃) |
| biological source | rabbit |
| explosive limit | 1.1%(V) |
| Water Solubility | Soluble in water (9g/L). |
| BRN | 1680303 |
| InChI | 1S/C8H14O3/c1-6(9)5-7(10)11-8(2,3)4/h5H2,1-4H3 |
| InChIKey | JKUYRAMKJLMYLO-UHFFFAOYSA-N |
| SMILES | CC(=O)CC(=O)OC(C)(C)C |
| LogP | 0.67-1.41 at 20℃ |
| CAS DataBase Reference | 1694-31-1(CAS DataBase Reference) |
| FDA UNII | 1D3DOS61GX |
| NIST Chemistry Reference | Butanoic acid, 3-oxo-, 1,1-dimethylethyl ester(1694-31-1) |
| EPA Substance Registry System | tert-Butyl acetoacetate (1694-31-1) |
| UNSPSC Code | 12352203 |
| NACRES | NA.41 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H227 | |||||||||
| Precautionary statements | P210e-P280a-P370+P378a-P501a-P210-P280-P370+P378-P403+P235-P501 | |||||||||
| PPE | Eyeshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 24/25 | |||||||||
| RIDADR | 3272 | |||||||||
| WGK Germany | 1 | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 3.2 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29183000 | |||||||||
| Storage Class | 10 - Combustible liquids | |||||||||
| NFPA 704 |
|
tert-Butyl acetoacetate price More Price(42)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SAB4502632 | Anti-Actin-pan, C-Terminal antibody produced in rabbit affinity isolated antibody | 100 μg | $522 | 2025-07-31 | Buy | |
| Sigma-Aldrich | SAB1305554 | MONOCLONAL ANTI-BETA-ACTIN antibody produced in mouse clone 137CT26.1.1, IgG fraction of antiserum, buffered aqueous solution | 400 μL | $496 | 2025-07-31 | Buy | |
| Sigma-Aldrich | SAB1305546 | MONOCLONAL ANTI-BETA-ACTIN antibody produced in mouse clone 8H10D10, IgG fraction of antiserum, buffered aqueous solution | 400 μL | $496 | 2025-07-31 | Buy | |
| Sigma-Aldrich | 537594 | tert-Butyl acetoacetate reagent grade, 98% | 1694-31-1 | 1l | $258 | 2025-07-31 | Buy |
| Sigma-Aldrich | 537594 | tert-Butyl acetoacetate reagent grade, 98% | 1694-31-1 | 4l | $402 | 2025-07-31 | Buy |
tert-Butyl acetoacetate Chemical Properties,Uses,Production
Description
Tert-Butyl acetoacetate is a reagent used to acetoacetylate hydroxyl-bearing coatings resins, such as polyesters, acrylics, cellulosics, and epoxies. It can be used as an acetoacetylating reagent in pharmaceutical, agrichemical, and pigment applications. It is used as an intermediate for the syntheses of different organic chemicals. For instance, it may be used to synthesize various acetoacetic acid derivatives, acetoacetates, acetoacetamides, 1-(diethylamino)-2-acetoacetoxypropane, (S)-tert-butyl 3-hydroxybutyrate, benzothiazole β-keto ester derivatives, and 3,4-disubstituted pyrroles.
Chemical Properties
liquid
Uses
Intermediate for the syntheses of different organic chemicals. Product Data Sheet
Uses
tert-Butyl acetoacetate is used as intermediate for the syntheses of different organic chemicals. Raw material in pharmaceutical Industry, In agrochemical industry. Reagent for Acyloin synthesis and ?,β - unsaturated ketones synthesis.
General Description
tert-Butyl acetoacetate (t-BAA) is a cheap and easy to store commercial reagent. Reaction demonstrated that the more hindered tert-butyl acetoacetate (t-BAA, la) is ca.15-20-fold more reactive than the more commonly used methyl or ethyl analogs. It is widely employed as an acetoacetylating reagent.
Flammability and Explosibility
Flammable
Biochem/physiol Actions
β-Actin modulates cell growth, migration and the G-actin pool. Mutations in ACTB leads to pleiotropic developmental disorder.
Synthesis
In the reaction vessel, add tert-butanol and catalyst; said catalyst is selected from fatty amine catalyst or tertiary amine catalyst; or, the catalyst is a fatty amine catalyst and tertiary amine catalyst, catalyst is one or several kinds of arbitrary ratio mixing; heating to 20 ~ 120 ??, dropwise addition of bis(vinylidene) ketone, the reaction process reaction temperature is controlled in the range of 20 ~ 150 ??, the end of the dropwise addition, the control of the temperature at The reaction temperature is controlled at 20-150 ??, the end of dropwise addition, control the temperature at 20-150 ?? holding time of 0.5-8 hours to end, to get the crude tert-butyl acetoacetate ester; said tert-butanol and bis(vinylidene) ketone molar ratio of 1-2:1, the amount of catalyst added for the total amount of 0.1wt% to 2wt%. Using this process to synthesize tert-butyl acetoacetate, the conversion rate of bis(vinyl ketone) reaches 100%, the yield of the finished product reaches more than 94%, and the product content reaches more than 99%.
Purification Methods
Distil it under reduced pressure through a short column. [Lawesson et al. Org Synth Coll Vol V 155 1973, Lawesson et al. Org Synth 42 28 1962, Beilstein 3 IV 1536.] HARMFUL VAPOUR.
tert-Butyl acetoacetate Preparation Products And Raw materials
Raw materials
Preparation Products
1of3
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Yanxi Chemical Co., Ltd. | +8618531123677 | faithe@yan-xi.com | China | 5853 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5242 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| airuikechemical co., ltd. | +86-18353166132 | sales02@airuikechemical.com | China | 983 | 58 |
| Hebei Zhuanglai Chemical Trading Co Ltd | +86-16264648883 | niki@zlchemi.com | China | 7245 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13676 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21597 | 55 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +8618949832763 | info@tnjchem.com | China | 2988 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29832 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8615060885618 | sales@amoychem.com | China | 6369 | 58 |
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- Jan 2，2020
View Lastest Price from tert-Butyl acetoacetate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-12-01 | tert-Butyl acetoacetate
1694-31-1
|
US $0.00 / kg | 1kg | 99% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | |
 |
2025-06-27 | tert-Butyl acetoacetate
1694-31-1
|
US $30.00-10.00 / KG | 50KG | 99% | 500000kg | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2025-06-20 | tert-Butyl acetoacetate
1694-31-1
|
US $0.00 / kg | 1kg | 0.99 | 20 tons | Hebei Yanxi Chemical Co., Ltd. |
-
- tert-Butyl acetoacetate
1694-31-1
- US $0.00 / kg
- 99%
- Shaanxi Dideu New Materials Co. Ltd
-
- tert-Butyl acetoacetate
1694-31-1
- US $30.00-10.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- tert-Butyl acetoacetate
1694-31-1
- US $0.00 / kg
- 0.99
- Hebei Yanxi Chemical Co., Ltd.
